Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) mazEF/MazE-MazF
Location 2294432..2295012 Replicon chromosome
Accession NZ_CP040896
Organism Hymenobacter jejuensis strain 17J68-5

Toxin (Protein)


Gene name mazF Uniprot ID -
Locus tag FHG12_RS09380 Protein ID WP_139515484.1
Coordinates 2294432..2294692 (+) Length 87 a.a.

Antitoxin (Protein)


Gene name mazE Uniprot ID -
Locus tag FHG12_RS09385 Protein ID WP_139515485.1
Coordinates 2294680..2295012 (+) Length 111 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
FHG12_RS09365 2291375..2292145 - 771 WP_139515481.1 alpha/beta hydrolase -
FHG12_RS09370 2292201..2293133 - 933 WP_139515482.1 LysR family transcriptional regulator -
FHG12_RS09375 2293484..2293939 + 456 WP_139515483.1 hypothetical protein -
FHG12_RS09380 2294432..2294692 + 261 WP_139515484.1 AbrB/MazE/SpoVT family DNA-binding domain-containing protein Toxin
FHG12_RS09385 2294680..2295012 + 333 WP_139515485.1 type II toxin-antitoxin system PemK/MazF family toxin Antitoxin
FHG12_RS09390 2295072..2295461 - 390 WP_139515486.1 hypothetical protein -
FHG12_RS09395 2295546..2296016 - 471 WP_139515487.1 hypothetical protein -
FHG12_RS09400 2296031..2297428 - 1398 WP_139515488.1 insulinase family protein -
FHG12_RS09405 2297437..2298867 - 1431 WP_139515489.1 insulinase family protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin


No domain identified.


Antitoxin

mRNA interferase PemK-like

(6-108)


Sequences

Toxin        


Download         Length: 87 a.a.        Molecular weight: 9869.15 Da        Isoelectric Point: 4.6234

>T127189 WP_139515484.1 NZ_CP040896:2294432-2294692 [Hymenobacter jejuensis]
MNTRIIRVGNSQGIVLPKKLLQQYHLVGEVDLQPTVEGLLIKPVAKPRREGWDERFQHAIAQGQTPEGELLEGFSDDAFE
ETEWQW

Download         Length: 261 bp

>T127189 NZ_CP040896:2294432-2294692 [Hymenobacter jejuensis]
ATGAACACGCGCATAATACGAGTAGGCAATTCGCAAGGAATTGTGCTGCCCAAGAAGCTACTGCAACAGTATCACCTCGT
CGGCGAGGTCGACTTACAGCCCACGGTTGAAGGCCTGCTCATCAAGCCAGTGGCAAAGCCCCGCCGCGAAGGGTGGGACG
AGCGCTTTCAACACGCGATTGCCCAGGGCCAGACCCCAGAGGGCGAACTGCTGGAGGGCTTTTCTGATGACGCCTTTGAG
GAAACCGAATGGCAGTGGTAG

Antitoxin


Download         Length: 111 a.a.        Molecular weight: 12639.60 Da        Isoelectric Point: 8.7371

>AT127189 WP_139515485.1 NZ_CP040896:2294680-2295012 [Hymenobacter jejuensis]
MAVVAVQRFEVWLVNLDPTQGSEINKTRPCVVLSPDEMNRYLRTVTIAALTSTRRDYPSRIDCTFQGKEGQVALDHIRSV
DKTRLVRRLGMLPKATAQEICDRLQEIFQY

Download         Length: 333 bp

>AT127189 NZ_CP040896:2294680-2295012 [Hymenobacter jejuensis]
ATGGCAGTGGTAGCGGTGCAACGCTTCGAGGTGTGGCTCGTCAACCTCGACCCCACCCAAGGCAGCGAAATCAACAAGAC
CCGTCCGTGCGTAGTGCTTTCGCCCGACGAGATGAACCGCTACCTGCGCACGGTCACCATTGCGGCGCTGACCAGCACCC
GGCGCGATTATCCCTCCCGCATCGATTGCACCTTCCAGGGCAAGGAAGGGCAGGTAGCCCTAGATCATATTCGGTCGGTT
GATAAAACCCGCTTGGTGCGTCGTTTGGGCATGCTGCCCAAAGCCACTGCACAAGAGATATGCGACCGGTTGCAAGAGAT
CTTTCAATATTAA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References