Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) mazF-pemI/PRK09907-MazE
Location 428259..428845 Replicon chromosome
Accession NZ_CP040882
Organism Sutterella faecalis strain KGMB03119

Toxin (Protein)


Gene name mazF Uniprot ID -
Locus tag FG381_RS01685 Protein ID WP_139687242.1
Coordinates 428504..428845 (+) Length 114 a.a.

Antitoxin (Protein)


Gene name pemI Uniprot ID -
Locus tag FG381_RS01680 Protein ID WP_139687241.1
Coordinates 428259..428504 (+) Length 82 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
FG381_RS01650 423454..423864 + 411 WP_139687235.1 PD-(D/E)XK nuclease domain-containing protein -
FG381_RS01655 424074..424577 - 504 WP_139687236.1 GNAT family N-acetyltransferase -
FG381_RS01660 424577..424843 - 267 WP_165697796.1 DUF1778 domain-containing protein -
FG381_RS01665 425796..426350 + 555 WP_139687238.1 helix-turn-helix domain-containing protein -
FG381_RS01670 426399..427199 + 801 WP_139687239.1 hypothetical protein -
FG381_RS01675 427267..427944 + 678 WP_139687240.1 hypothetical protein -
FG381_RS01680 428259..428504 + 246 WP_139687241.1 PbsX family transcriptional regulator Antitoxin
FG381_RS01685 428504..428845 + 342 WP_139687242.1 endoribonuclease MazF Toxin
FG381_RS01690 428927..430186 - 1260 WP_139687243.1 autotransporter outer membrane beta-barrel domain-containing protein -
FG381_RS01695 430152..431531 - 1380 WP_139687244.1 hypothetical protein -
FG381_RS01700 431894..433816 + 1923 WP_139687245.1 hypothetical protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Genomic island - - 422116..431531 9415


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

mRNA interferase PemK-like

(9-108)

Antitoxin

Antitoxin PemI-like

(1-80)


Sequences

Toxin        


Download         Length: 114 a.a.        Molecular weight: 12562.38 Da        Isoelectric Point: 5.6419

>T127150 WP_139687242.1 NZ_CP040882:428504-428845 [Sutterella faecalis]
MPNPYVPECGDIVWLDFNPVLGHEQGGRRPALVLSPSSYNGKTGLMICCPMTTKKKGYPFEVVLSENPDSVVLSDQITTV
DWTQRHCDFKGRITTNQLADVRDNISLLISLPN

Download         Length: 342 bp

>T127150 NZ_CP040882:428504-428845 [Sutterella faecalis]
ATGCCAAACCCTTATGTTCCAGAATGCGGAGATATTGTTTGGCTTGATTTTAATCCAGTCCTGGGCCATGAGCAGGGTGG
ACGCCGCCCTGCTTTAGTTTTATCTCCTTCTTCCTATAATGGGAAAACTGGCCTGATGATTTGCTGCCCCATGACGACAA
AGAAGAAAGGATATCCTTTTGAAGTTGTTTTATCAGAAAACCCAGATTCAGTAGTTCTATCTGATCAAATAACAACAGTC
GATTGGACGCAACGTCATTGCGATTTTAAAGGCCGCATTACGACAAATCAGTTAGCTGATGTCCGAGATAATATTTCCCT
TCTTATATCACTTCCGAACTAA

Antitoxin


Download         Length: 82 a.a.        Molecular weight: 9363.99 Da        Isoelectric Point: 9.9674

>AT127150 WP_139687241.1 NZ_CP040882:428259-428504 [Sutterella faecalis]
MQTSLKQWGNSIAVRIPQALLEQGHFQKDDMFDIKICNNEIVLKRIISSRQKKLETMLSKITPQNIHERMDFGAPIGKEL
L

Download         Length: 246 bp

>AT127150 NZ_CP040882:428259-428504 [Sutterella faecalis]
ATGCAAACGTCGCTTAAACAATGGGGAAACAGTATTGCGGTTCGTATCCCGCAGGCCTTGCTTGAACAAGGGCATTTTCA
GAAAGATGACATGTTCGATATAAAGATCTGCAATAATGAGATCGTTTTGAAACGCATTATCTCCAGTCGTCAAAAAAAAT
TAGAAACCATGCTGTCTAAAATCACACCTCAAAACATTCATGAACGCATGGATTTTGGAGCTCCGATTGGAAAGGAATTA
CTGTAA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References