Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) rlegTA/AbiEii-AbiEi
Location 2182644..2184154 Replicon chromosome
Accession NZ_CP040871
Organism Thermomonas sp. SY21

Toxin (Protein)


Gene name rlegT Uniprot ID -
Locus tag FHQ07_RS10330 Protein ID WP_206202317.1
Coordinates 2183243..2184154 (+) Length 304 a.a.

Antitoxin (Protein)


Gene name rlegA Uniprot ID -
Locus tag FHQ07_RS10325 Protein ID WP_139716726.1
Coordinates 2182644..2183246 (+) Length 201 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
FHQ07_RS10290 2177955..2178512 - 558 WP_139716720.1 RNA pyrophosphohydrolase -
FHQ07_RS10300 2178888..2180117 + 1230 WP_139716721.1 integrase arm-type DNA-binding domain-containing protein -
FHQ07_RS10305 2180129..2180590 + 462 WP_139716722.1 hypothetical protein -
FHQ07_RS10310 2180679..2180900 + 222 WP_139716723.1 AlpA family transcriptional regulator -
FHQ07_RS10315 2180905..2181396 + 492 WP_139716724.1 helix-turn-helix domain-containing protein -
FHQ07_RS10320 2181389..2182513 + 1125 WP_139716725.1 tyrosine-type recombinase/integrase -
FHQ07_RS10325 2182644..2183246 + 603 WP_139716726.1 type IV toxin-antitoxin system AbiEi family antitoxin domain-containing protein Antitoxin
FHQ07_RS10330 2183243..2184154 + 912 WP_206202317.1 nucleotidyl transferase AbiEii/AbiGii toxin family protein Toxin
FHQ07_RS10335 2184151..2186199 + 2049 WP_139716727.1 type I restriction-modification system subunit M -
FHQ07_RS10340 2186280..2187407 + 1128 WP_139716728.1 restriction endonuclease subunit S -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Genomic island - - 2178888..2187407 8519


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Nucleotidyl transferase AbiEii toxin, Type IV TA system

(40-268)

Antitoxin

Transcriptional regulator, AbiEi antitoxin

(10-51)


Sequences

Toxin        


Download         Length: 304 a.a.        Molecular weight: 33746.63 Da        Isoelectric Point: 5.7353

>T127139 WP_206202317.1 NZ_CP040871:2183243-2184154 [Thermomonas sp. SY21]
VTKPGPAANRIASIRQRLLERARIRGEDFQLVLDRYAVERLLYRLSISPHRDQFLLKGALLFALWFDQPHRPTRDADLLG
FGSPDPERLAAIVAELCAIEDEDGLRFDVGSMTVEPIREEAAYEGLRIRLLAFLGDARCHLQWDVGFGDAVTPAPADVDY
PVLLEGMPAPRLRVYPRDTVFAEKLEAIATLGIANSRMKDYFDLLALMREQAMAPATLAEAIRATFQRRGTAPPEGVPFG
LTDAFATDAQKQSQWAAFLRRNRLTAPALAEVVAELRAFFIALDPWAGGRHPGHDQPQPQQTP

Download         Length: 912 bp

>T127139 NZ_CP040871:2183243-2184154 [Thermomonas sp. SY21]
GTGACCAAGCCGGGACCTGCGGCCAATCGCATCGCCTCGATCCGGCAACGCCTGCTGGAGCGCGCGCGGATACGCGGTGA
GGATTTCCAACTCGTCCTCGATCGCTACGCCGTGGAGCGGCTGCTGTATCGGCTGTCGATCTCGCCGCATCGCGACCAGT
TCCTACTCAAGGGCGCACTGCTGTTCGCACTCTGGTTCGACCAGCCGCACCGGCCCACGCGCGATGCCGACCTTCTTGGC
TTCGGGTCGCCGGATCCCGAACGGCTGGCCGCCATCGTCGCCGAGCTCTGCGCCATCGAGGACGAAGATGGTCTGCGATT
CGATGTCGGCTCGATGACGGTCGAACCCATCCGTGAGGAAGCCGCATACGAAGGTCTGCGGATCCGCCTGCTGGCCTTCC
TCGGCGACGCGCGATGCCATCTGCAGTGGGACGTAGGCTTCGGCGACGCGGTCACGCCGGCGCCGGCAGACGTCGACTAT
CCCGTGCTGCTGGAAGGCATGCCGGCACCCCGTCTGCGGGTCTATCCGCGCGATACCGTCTTCGCCGAGAAGCTGGAAGC
CATCGCCACCTTGGGCATCGCCAACAGCCGGATGAAGGACTACTTCGACCTGCTGGCGCTGATGCGCGAGCAGGCGATGG
CGCCCGCCACCTTGGCCGAGGCCATCCGCGCGACCTTCCAGCGCCGCGGCACCGCGCCGCCCGAGGGCGTGCCGTTCGGC
CTGACCGACGCCTTTGCCACCGATGCGCAGAAGCAGTCCCAGTGGGCCGCCTTCCTGCGCCGCAACCGGCTGACCGCCCC
GGCACTTGCCGAGGTGGTGGCGGAACTCAGGGCCTTTTTCATTGCGCTGGATCCGTGGGCTGGCGGCCGCCATCCCGGCC
ACGACCAGCCCCAACCCCAGCAGACACCATGA

Antitoxin


Download         Length: 201 a.a.        Molecular weight: 21846.64 Da        Isoelectric Point: 10.3775

>AT127139 WP_139716726.1 NZ_CP040871:2182644-2183246 [Thermomonas sp. SY21]
MTDPAAIAKALIQHKGAVRSRELVDAGVARVQLSRLVAAGELIRLARGVYTAPGVVLPGSEEGVLVVAERIPEARLCLLT
ALRLHGLTTQAPFEVWIAIGNKDRLPRLDWPPLRVLRFSGEALTAGLETRTMGSKQVRVTNVAKTVADCFKFRNLVGLDV
AIEALRDALRARATSVDELWKYAQICRVTTVMRPYLEALA

Download         Length: 603 bp

>AT127139 NZ_CP040871:2182644-2183246 [Thermomonas sp. SY21]
ATGACCGATCCGGCGGCCATCGCGAAAGCACTTATCCAGCACAAGGGCGCGGTCCGCTCCCGGGAGCTGGTGGACGCCGG
CGTAGCGCGCGTGCAGCTCTCGCGCCTGGTGGCGGCCGGCGAGCTGATCCGGCTGGCGCGCGGCGTCTACACCGCACCCG
GGGTGGTGCTGCCCGGCAGTGAGGAAGGCGTACTGGTGGTCGCCGAGCGCATCCCCGAGGCGAGACTGTGCCTACTGACG
GCCCTGCGGCTGCATGGCCTGACCACCCAGGCGCCGTTCGAGGTGTGGATCGCCATCGGCAACAAGGACCGGCTGCCGCG
TCTGGATTGGCCCCCGCTGCGCGTTCTCCGTTTTTCAGGCGAGGCCCTCACCGCAGGGCTCGAGACTCGCACGATGGGCA
GCAAGCAGGTGCGCGTCACCAATGTCGCCAAGACGGTGGCGGACTGCTTCAAGTTTCGCAATCTGGTGGGGCTGGATGTG
GCCATCGAAGCCCTGCGCGATGCGCTGCGCGCGCGCGCCACCAGCGTCGACGAGCTGTGGAAGTACGCGCAGATTTGCCG
CGTCACCACGGTCATGCGGCCCTACCTGGAGGCGCTGGCGTGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References