Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relBE/Phd(antitoxin)
Location 804974..805539 Replicon chromosome
Accession NZ_CP040871
Organism Thermomonas sp. SY21

Toxin (Protein)


Gene name relE Uniprot ID -
Locus tag FHQ07_RS03805 Protein ID WP_139715424.1
Coordinates 805219..805539 (+) Length 107 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID -
Locus tag FHQ07_RS03800 Protein ID WP_139715423.1
Coordinates 804974..805231 (+) Length 86 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
FHQ07_RS03770 800460..800822 + 363 WP_206202347.1 ACT domain-containing protein -
FHQ07_RS03775 801660..802250 + 591 WP_139715419.1 hypothetical protein -
FHQ07_RS03780 802722..803216 + 495 WP_139715420.1 hypothetical protein -
FHQ07_RS03785 803715..804083 + 369 WP_139715387.1 DUF5329 domain-containing protein -
FHQ07_RS03790 804162..804452 - 291 WP_139715421.1 XRE family transcriptional regulator -
FHQ07_RS03795 804449..804790 - 342 WP_139715422.1 type II toxin-antitoxin system RelE/ParE family toxin -
FHQ07_RS03800 804974..805231 + 258 WP_139715423.1 type II toxin-antitoxin system prevent-host-death family antitoxin Antitoxin
FHQ07_RS03805 805219..805539 + 321 WP_139715424.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
FHQ07_RS03810 806782..807663 + 882 WP_139715425.1 hypothetical protein -
FHQ07_RS03815 808768..809184 + 417 WP_139715426.1 hypothetical protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Genomic island - - 786898..828678 41780
- inside Integron - - 759010..827378 68368


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(4-90)

Antitoxin

Type II toxin-antitoxin system, antitoxin Phd/YefM

(1-67)


Sequences

Toxin        


Download         Length: 107 a.a.        Molecular weight: 12150.02 Da        Isoelectric Point: 9.4833

>T127135 WP_139715424.1 NZ_CP040871:805219-805539 [Thermomonas sp. SY21]
MAEIVWSEPALADLDAIADYIALENPVAASELVKRIFGHIEQLVNHPESGSRPQELGKSRYRQIVEPPCHVFYRYDGHKV
FILHVMRSERLLRKGQLAKRSKQAKT

Download         Length: 321 bp

>T127135 NZ_CP040871:805219-805539 [Thermomonas sp. SY21]
ATGGCTGAAATAGTCTGGTCAGAGCCCGCTCTCGCGGATCTTGACGCAATTGCCGACTACATCGCACTGGAGAACCCAGT
TGCGGCGTCTGAGCTAGTCAAGCGCATCTTTGGCCACATCGAACAGCTCGTGAATCACCCTGAGAGCGGGAGTCGCCCGC
AAGAGCTTGGGAAATCGCGCTACCGTCAGATCGTGGAGCCGCCCTGCCACGTCTTCTACCGTTATGACGGGCACAAGGTT
TTCATCCTGCACGTCATGCGTTCGGAACGATTGCTCCGCAAGGGCCAGCTTGCCAAGCGCTCCAAGCAAGCAAAGACCTA
A

Antitoxin


Download         Length: 86 a.a.        Molecular weight: 9743.33 Da        Isoelectric Point: 9.7317

>AT127135 WP_139715423.1 NZ_CP040871:804974-805231 [Thermomonas sp. SY21]
MRTELVTTLKRQATELLSDIERDKEPILITQHGLPSAYLLDVETYQLMQQRMAILEGIARGEQALAEGRVATHTQAKKRL
ARWLK

Download         Length: 258 bp

>AT127135 NZ_CP040871:804974-805231 [Thermomonas sp. SY21]
ATGCGCACTGAACTCGTCACAACTCTGAAGCGGCAGGCCACTGAACTCCTCTCAGATATTGAGCGGGATAAAGAGCCAAT
TCTCATTACCCAGCATGGCCTGCCAAGCGCCTATCTCCTGGATGTTGAGACTTATCAGCTCATGCAACAGCGCATGGCCA
TCCTTGAAGGCATTGCCCGCGGAGAGCAAGCCCTAGCAGAAGGCCGTGTGGCAACTCATACGCAAGCAAAGAAGCGTCTC
GCCAGATGGCTGAAATAG

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References