Detailed information of TA system TA127133

Bioinformatically predicted

Overview

TA module

• Type: II
• Classification (family/domain): chpIK/PemK(toxin)
• Location: 773276..773840
• Replicon: chromosome
• Accession: NZ_CP040871
• Organism: Thermomonas sp. SY21

Toxin (Protein)

• Gene name: chpK
• Uniprot ID: -
• Locus tag: FHQ07_RS03600
• Protein ID: WP_139715386.1
• Coordinates: 773499..773840 (+)
• Length: 114 a.a.

Antitoxin (Protein)

• Gene name: chpI
• Uniprot ID: -
• Locus tag: FHQ07_RS03595
• Protein ID: WP_139715385.1
• Coordinates: 773276..773512 (+)
• Length: 79 a.a.

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
FHQ07_RS03565	768457..768837	+	381	WP_139715381.1	MAPEG family protein	-
FHQ07_RS03570	769392..769700	+	309	WP_139715382.1	hypothetical protein	-
FHQ07_RS14450	771607..771714	+	108	WP_206202370.1	excalibur calcium-binding domain-containing protein	-
FHQ07_RS03585	771838..772695	+	858	WP_139715383.1	hypothetical protein	-
FHQ07_RS03590	772724..773122	+	399	WP_139715384.1	hypothetical protein	-
FHQ07_RS03595	773276..773512	+	237	WP_139715385.1	ribbon-helix-helix domain-containing protein	Antitoxin
FHQ07_RS03600	773499..773840	+	342	WP_139715386.1	type II toxin-antitoxin system PemK/MazF family toxin	Toxin
FHQ07_RS03605	777258..777626	+	369	WP_139715387.1	DUF5329 domain-containing protein	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)
	-	inside	Integron	-	-	759010..827378	68368

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

• mRNA interferase PemK-like (1-112)

Antitoxin

No domain identified.

Sequences

Toxin

Protein

• Length: 114 a.a.
• Molecular weight: 11852.89 Da
• Isoelectric Point: 10.8134

>T127133 WP_139715386.1 NZ_CP040871:773499-773840 [Thermomonas sp. SY21]
MKRGEIWWADIPNPVGSGPGYKRPVLVVQANPFNASRISTVIVATVTSNLALAEAPGNVRIGKSDSGLPQPSVVNVSQLI
TLDRAILSKKVKALPGATMDKVDAGLKLVLSLP

Nucleotide

• Length: 342 bp

>T127133 NZ_CP040871:773499-773840 [Thermomonas sp. SY21]
ATGAAGCGTGGTGAAATTTGGTGGGCCGACATTCCAAACCCTGTTGGTTCTGGCCCTGGCTACAAGCGGCCTGTTCTAGT
CGTACAGGCCAATCCGTTCAATGCGAGTCGCATTTCTACTGTCATTGTTGCGACCGTCACCTCAAACCTCGCTTTAGCCG
AGGCTCCAGGCAATGTTCGGATAGGGAAATCTGACTCAGGCTTGCCTCAACCATCGGTTGTGAACGTTTCGCAACTGATC
ACGCTTGATCGTGCAATTCTCTCCAAGAAGGTCAAAGCGCTGCCGGGCGCAACCATGGACAAGGTAGACGCCGGGTTAAA
GCTGGTTCTTTCCCTTCCATGA

Antitoxin

Protein

• Length: 79 a.a.
• Molecular weight: 8613.83 Da
• Isoelectric Point: 6.4580

>AT127133 WP_139715385.1 NZ_CP040871:773276-773512 [Thermomonas sp. SY21]
MKVAISLPDPVFSAAEKLAHRMRVSRSQLYAQAIEEYLGKRQDTLITERLNALYASEQNSIDPAMAAAQLGAIGHEAW

Nucleotide

• Length: 237 bp

>AT127133 NZ_CP040871:773276-773512 [Thermomonas sp. SY21]
ATGAAAGTCGCCATCTCTCTGCCAGACCCCGTCTTCTCCGCCGCCGAGAAGCTTGCTCATCGGATGCGCGTGTCCCGTAG
CCAGCTCTATGCGCAAGCCATCGAGGAGTATCTCGGAAAGCGCCAAGACACACTGATCACTGAGCGCCTGAACGCCCTGT
ACGCTTCGGAGCAGAACTCGATTGATCCTGCCATGGCCGCGGCCCAGCTCGGAGCGATCGGCCATGAAGCGTGGTGA