Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) PumA-relB/COG3657-dnstrm_HI1420
Location 908288..908877 Replicon chromosome
Accession NZ_CP040863
Organism Rodentibacter heylii strain G1

Toxin (Protein)


Gene name PumA Uniprot ID -
Locus tag FEE42_RS04500 Protein ID WP_164027814.1
Coordinates 908288..908587 (+) Length 100 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID -
Locus tag FEE42_RS04505 Protein ID WP_077493439.1
Coordinates 908584..908877 (+) Length 98 a.a.

Genomic Context

FEE42_RS04485FEE42_RS04500FEE42_RS04505FEE42_RS04520FEE42_RS04525FEE42_RS04530FEE42_RS04460FEE42_RS04465FEE42_RS04470FEE42_RS04475FEE42_RS04480FEE42_RS04490FEE42_RS04510FEE42_RS04515FEE42_RS04535FEE42_RS04540FEE42_RS04545
Location: 907041..907601 (561 bp)
Type: Others
Protein ID: WP_164027813.1
Location: 908288..908587 (300 bp)
Type: Toxin
Protein ID: WP_164027814.1
Location: 908584..908877 (294 bp)
Type: Antitoxin
Protein ID: WP_077493439.1
Location: 909922..910104 (183 bp)
Type: Others
Protein ID: WP_135968557.1
Location: 910133..910588 (456 bp)
Type: Others
Protein ID: WP_135968556.1
Location: 910870..911529 (660 bp)
Type: Others
Protein ID: WP_164027817.1
Location: 903714..904217 (504 bp)
Type: Others
Protein ID: WP_164027808.1
Location: 904235..905635 (1401 bp)
Type: Others
Protein ID: WP_164027809.1
Location: 905838..906176 (339 bp)
Type: Others
Protein ID: WP_164027810.1
Location: 906149..906697 (549 bp)
Type: Others
Protein ID: WP_164027811.1
Location: 906690..906935 (246 bp)
Type: Others
Protein ID: WP_164027812.1
Location: 907655..907924 (270 bp)
Type: Others
Protein ID: WP_152634407.1
Location: 908917..909285 (369 bp)
Type: Others
Protein ID: WP_164027815.1
Location: 909275..909835 (561 bp)
Type: Others
Protein ID: WP_164027816.1
Location: 911566..911973 (408 bp)
Type: Others
Protein ID: WP_164028809.1
Location: 911984..912526 (543 bp)
Type: Others
Protein ID: WP_164027818.1
Location: 912523..913158 (636 bp)
Type: Others
Protein ID: WP_167514392.1
ToxinAntitoxinOther genes
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Locus tag
Coordinates
Strand
Size (bp)
Protein ID
Product
Description
FEE42_RS04460903714..904217-504WP_164027808.1terminase small subunit-
FEE42_RS04465904235..905635-1401WP_164027809.1site-specific DNA-methyltransferase-
FEE42_RS04470905838..906176-339WP_164027810.1DUF2570 family protein-
FEE42_RS04475906149..906697-549WP_164027811.1lysozyme-
FEE42_RS04480906690..906935-246WP_164027812.1hypothetical protein-
FEE42_RS04485907041..907601+561WP_164027813.1hypothetical protein-
FEE42_RS04490907655..907924-270WP_152634407.1hypothetical protein-
FEE42_RS04500908288..908587+300WP_164027814.1type II toxin-antitoxin system RelE/ParE family toxinToxin
FEE42_RS04505908584..908877+294WP_077493439.1putative addiction module antidote proteinAntitoxin
FEE42_RS04510908917..909285-369WP_164027815.1antitermination protein-
FEE42_RS04515909275..909835-561WP_164027816.1recombination protein NinG-
FEE42_RS04520909922..910104+183WP_135968557.1type II toxin-antitoxin system HicA family toxin-
FEE42_RS04525910133..910588+456WP_135968556.1type II toxin-antitoxin system HicB family antitoxin-
FEE42_RS04530910870..911529+660WP_164027817.1KilA-N domain-containing protein-
FEE42_RS04535911566..911973-408WP_164028809.1recombination protein NinB-
FEE42_RS04540911984..912526-543WP_164027818.1adenine methyltransferase-
FEE42_RS04545912523..913158-636WP_167514392.1replication P-

Associated MGEs

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MGE
detail
Similar
MGEs
Relative
position
MGE Type
Cargo ARG
Virulence gene
Coordinates
Length (bp)
-insideProphage--875164..977547102383


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Addiction module killer protein, predicted

(1-98)

Antitoxin

Cro/C1-type helix-turn-helix domain

(45-89)


Sequences

Toxin        


Download         Length: 100 a.a.        Molecular weight: 11274.10 Da        Isoelectric Point: 10.2800

>T127131 WP_164027814.1 NZ_CP040863:908288-908587 [Rodentibacter heylii]
MTIQIKTTLTFDNWLSKLKNIRAKAKINARIKRLQFGNFGDIKSVNDGIFELRIDEGQGYRIYLKNQNGVLVFLLCGGDK
STQEQDIKKAKQLAEELGL

Download         Length: 300 bp

>T127131 NZ_CP040863:908288-908587 [Rodentibacter heylii]
ATGACAATCCAAATTAAAACAACTTTAACTTTTGATAACTGGCTGAGCAAACTAAAGAATATTCGTGCTAAAGCTAAAAT
CAATGCACGAATCAAACGTTTACAGTTCGGAAACTTTGGCGATATTAAAAGTGTAAATGATGGCATTTTTGAATTACGCA
TAGATGAAGGACAAGGCTATCGAATTTATCTGAAAAATCAAAACGGTGTTTTAGTATTTTTACTATGTGGCGGAGACAAA
TCCACACAAGAACAAGATATCAAGAAAGCAAAACAACTTGCAGAGGAATTAGGATTATGA

Antitoxin


Download         Length: 98 a.a.        Molecular weight: 10806.29 Da        Isoelectric Point: 4.4488

>AT127131 WP_077493439.1 NZ_CP040863:908584-908877 [Rodentibacter heylii]
MTEQLKDFDIAEHLTSEEEIQLYLNEILQEDNVELILSALGDIARARNMSQIARDAGISREGLYKALSGSGNPTFATVMK
VMKALNLKFQVQQSSFA

Download         Length: 294 bp

>AT127131 NZ_CP040863:908584-908877 [Rodentibacter heylii]
ATGACAGAACAATTAAAAGATTTTGATATTGCAGAACATCTCACTTCCGAAGAGGAAATTCAGCTTTATCTCAACGAAAT
TTTACAAGAAGACAATGTTGAACTTATTTTATCTGCGCTTGGAGATATTGCCCGAGCACGTAATATGAGCCAAATTGCCC
GTGATGCAGGAATCAGCCGTGAAGGGCTTTATAAAGCATTATCCGGTTCAGGTAACCCAACTTTTGCTACCGTGATGAAA
GTTATGAAAGCATTAAACCTCAAATTCCAAGTTCAACAGTCGAGTTTTGCTTAA

Similar Proteins

Only experimentally validated proteins are listed.

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Protein
Organism
Identities (%)
Coverage (%)
Ha-value
No matching records found
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Protein
Organism
Identities (%)
Coverage (%)
Ha-value
No matching records found

Structures

Toxin

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Source
ID
Structure
No matching records found

Antitoxin

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Source
ID
Structure
No matching records found

References