127061

Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) sanaTA/AbiEii-DUF6088
Location 4660309..4661653 Replicon chromosome
Accession NZ_CP040817
Organism Dickeya zeae strain PL65

Toxin (Protein)


Gene name sanaT Uniprot ID -
Locus tag FGI21_RS20905 Protein ID WP_220177528.1
Coordinates 4660309..4661265 (-) Length 319 a.a.

Antitoxin (Protein)


Gene name sanaA Uniprot ID -
Locus tag FGI21_RS20910 Protein ID WP_033576632.1
Coordinates 4661258..4661653 (-) Length 132 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
FGI21_RS20875 (FGI21_21035) 4655919..4656047 + 129 Protein_4079 IS3 family transposase -
FGI21_RS20880 (FGI21_21040) 4656142..4656849 - 708 WP_220177526.1 2Fe-2S iron-sulfur cluster-binding protein -
FGI21_RS20885 (FGI21_21045) 4656836..4657243 + 408 Protein_4081 AraC family ligand binding domain-containing protein -
FGI21_RS20890 (FGI21_21050) 4657316..4657786 - 471 WP_168361982.1 cyanase -
FGI21_RS20895 (FGI21_21055) 4657814..4658473 - 660 WP_168361983.1 carbonic anhydrase -
FGI21_RS20900 (FGI21_21060) 4658584..4659471 + 888 WP_220177527.1 transcriptional regulator CynR -
FGI21_RS20905 (FGI21_21065) 4660309..4661265 - 957 WP_220177528.1 nucleotidyl transferase AbiEii/AbiGii toxin family protein Toxin
FGI21_RS20910 (FGI21_21070) 4661258..4661653 - 396 WP_033576632.1 DUF6088 family protein Antitoxin
FGI21_RS20915 (FGI21_21075) 4661900..4662194 - 295 Protein_4087 PIN domain-containing protein -
FGI21_RS20920 (FGI21_21080) 4662219..4662494 + 276 Protein_4088 baseplate protein -
FGI21_RS20925 (FGI21_21085) 4662503..4662922 + 420 WP_168361986.1 phage GP46 family protein -
FGI21_RS20935 (FGI21_21095) 4663631..4666081 + 2451 WP_168361987.1 DUF3772 domain-containing protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Nucleotidyl transferase AbiEii toxin, Type IV TA system

(34-302)

Antitoxin

Protein of unknown function DUF6088

(7-114)


Sequences

Toxin        


Download         Length: 319 a.a.        Molecular weight: 36798.20 Da        Isoelectric Point: 5.0579

>T127061 WP_220177528.1 NZ_CP040817:c4661265-4660309 [Dickeya zeae]
MDELTALFPDVADALGIESVSIVEKDYYIVELLRLLRHLTFDTHQLVFAGGTALSKAGISLNRMSEDVDIKLVPTANFLQ
QSSRSQRKNIRKDIIRTITESIVASRVFSFDDDYPRVTRDEYRYNEVPVRYPQMYSQIPCLRPFIKLELMETDLLESPET
RDICSLVTDVTKKGEMVRAFPCATIVSTQAEKLISMMRRTAASMRDLERTEDESLVRHIYDNFCIVREKGVNVAALTHFI
QECIEQDIARYGNQYPEFCESPVEELKKGLEELASNPVYKMRYQQFLAPMVFSEIRVSWEEAYSCFRQTVLSVLKSYR

Download         Length: 957 bp

>T127061 NZ_CP040817:c4661265-4660309 [Dickeya zeae]
ATGGATGAGTTAACAGCATTATTTCCTGACGTTGCTGATGCACTTGGAATTGAGTCTGTCTCTATAGTGGAGAAAGATTA
TTACATCGTTGAATTATTACGCCTGCTTCGGCATCTGACTTTTGATACGCATCAACTGGTTTTTGCCGGAGGTACAGCGT
TATCAAAAGCAGGAATATCGTTAAACCGGATGTCAGAAGATGTAGATATTAAGCTGGTTCCTACTGCTAATTTTTTGCAA
CAAAGCTCAAGAAGTCAGCGTAAGAATATACGTAAAGATATCATCCGAACGATTACCGAATCGATCGTTGCTTCCAGGGT
TTTTAGTTTTGACGATGACTATCCCAGAGTCACTCGCGATGAATATCGTTACAATGAAGTTCCCGTGCGTTATCCGCAAA
TGTATTCACAAATCCCTTGCCTGCGGCCATTTATTAAATTGGAGTTAATGGAAACAGACTTGCTTGAATCACCAGAAACG
CGTGATATTTGCTCATTGGTAACTGATGTCACGAAAAAAGGGGAAATGGTTCGAGCTTTTCCGTGTGCCACTATCGTCAG
TACGCAGGCTGAAAAGCTTATCTCGATGATGCGAAGAACAGCTGCAAGTATGCGTGATTTGGAACGAACAGAGGATGAAT
CACTGGTGCGCCATATCTACGACAATTTTTGTATTGTCAGAGAGAAAGGCGTTAATGTTGCCGCTTTAACCCATTTTATT
CAGGAATGTATTGAGCAAGATATTGCACGTTACGGTAATCAGTATCCTGAGTTCTGCGAATCGCCTGTTGAGGAACTCAA
AAAAGGGCTGGAAGAGCTGGCAAGTAATCCTGTTTATAAAATGCGCTATCAACAATTCTTAGCGCCAATGGTGTTTAGTG
AAATCCGCGTTTCATGGGAAGAAGCCTATTCCTGTTTTCGCCAAACCGTATTAAGTGTACTGAAATCATATCGCTAA

Antitoxin


Download         Length: 132 a.a.        Molecular weight: 14443.79 Da        Isoelectric Point: 11.0325

>AT127061 WP_033576632.1 NZ_CP040817:c4661653-4661258 [Dickeya zeae]
MTIKARIQSRLKRSKRYVFTRDDFKDLAGYDQVGRALRELVKEGQLLKVGYGVYTKARKNVITGRLMPASPGGSAAVVIE
ALERLKVDYRLADAASAYNSGKSTQVPASIEIKTPPRFKRVLSVGNSKLNG

Download         Length: 396 bp

>AT127061 NZ_CP040817:c4661653-4661258 [Dickeya zeae]
ATGACCATAAAAGCTCGTATTCAGTCGCGGCTGAAACGCTCGAAGCGTTATGTTTTCACTCGTGACGACTTCAAAGATCT
TGCTGGCTACGATCAAGTTGGCAGAGCGCTGCGTGAATTGGTAAAAGAAGGCCAACTGCTGAAAGTCGGTTATGGCGTCT
ATACCAAAGCGCGGAAAAATGTGATTACGGGTAGGCTAATGCCCGCCTCTCCCGGCGGCTCTGCTGCGGTGGTGATCGAA
GCGCTGGAGCGCCTGAAAGTGGACTATCGCCTGGCTGATGCAGCAAGCGCTTACAATAGCGGCAAGTCAACTCAGGTTCC
GGCGTCAATCGAAATCAAAACACCCCCACGTTTTAAGCGCGTGTTGTCAGTAGGGAATAGCAAGTTAAATGGATGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References