Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type IV Classification (family/domain) cptAB/Cpta(toxin)
Location 2418149..2418827 Replicon chromosome
Accession NZ_CP040817
Organism Dickeya zeae strain PL65

Toxin (Protein)


Gene name cptA Uniprot ID -
Locus tag FGI21_RS10710 Protein ID WP_220176783.1
Coordinates 2418149..2418580 (-) Length 144 a.a.

Antitoxin (Protein)


Gene name cptB Uniprot ID -
Locus tag FGI21_RS10715 Protein ID WP_038906203.1
Coordinates 2418561..2418827 (-) Length 89 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
FGI21_RS10690 (FGI21_10765) 2414072..2414788 - 717 WP_012883376.1 bifunctional protein-disulfide isomerase/oxidoreductase DsbC -
FGI21_RS10695 (FGI21_10770) 2414876..2415775 - 900 WP_220176782.1 site-specific tyrosine recombinase XerD -
FGI21_RS10700 (FGI21_10775) 2416039..2417364 + 1326 WP_168363478.1 MFS transporter -
FGI21_RS10705 (FGI21_10780) 2417542..2418060 + 519 WP_168363479.1 flavodoxin FldB -
FGI21_RS10710 (FGI21_10785) 2418149..2418580 - 432 WP_220176783.1 protein YgfX Toxin
FGI21_RS10715 (FGI21_10790) 2418561..2418827 - 267 WP_038906203.1 FAD assembly factor SdhE Antitoxin
FGI21_RS10720 (FGI21_10795) 2419136..2420116 + 981 WP_220176784.1 tRNA-modifying protein YgfZ -
FGI21_RS10725 (FGI21_10800) 2420193..2420843 - 651 WP_019846261.1 hemolysin III family protein -
FGI21_RS10730 (FGI21_10805) 2421056..2421664 + 609 WP_019846260.1 HD domain-containing protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Inner membrane protein YgfX

(2-132)

Antitoxin

Flavinator of succinate dehydrogenase

(7-79)


Sequences

Toxin        


Download         Length: 144 a.a.        Molecular weight: 16966.64 Da        Isoelectric Point: 11.7122

>T127059 WP_220176783.1 NZ_CP040817:c2418580-2418149 [Dickeya zeae]
VAQWQCDLRVSWRMQLFSLLTHGFLMLMILLAPWPDGYAPLWLGLVTLVVFDFVRSQRSIKSRQGEISLRGDNQLRWQQR
DWQIVRRPWFMRNGVLLSLRAVDSKGQQRLWLASDSMGSEEWRLLRQQLQQPTLHGTESSRHH

Download         Length: 432 bp

>T127059 NZ_CP040817:c2418580-2418149 [Dickeya zeae]
GTGGCCCAGTGGCAATGTGATTTACGCGTATCCTGGCGTATGCAGTTGTTTTCGCTGCTGACGCACGGATTTCTGATGCT
GATGATCCTGCTGGCTCCCTGGCCGGACGGCTACGCACCGCTGTGGCTCGGGTTAGTGACGCTGGTCGTGTTTGACTTTG
TGCGTAGCCAGCGAAGCATCAAATCGCGCCAGGGGGAGATTTCCCTGCGTGGTGATAACCAACTGCGCTGGCAGCAACGT
GACTGGCAGATTGTCCGGCGACCGTGGTTCATGCGTAACGGCGTGTTGTTGTCGCTACGGGCGGTGGATAGTAAAGGGCA
ACAGCGTTTGTGGCTGGCGTCAGACAGTATGGGGAGTGAGGAATGGCGGCTGTTACGTCAACAGCTGCAGCAGCCTACGC
TGCATGGAACGGAATCTTCCCGCCATCATTAA

Antitoxin


Download         Length: 89 a.a.        Molecular weight: 10446.96 Da        Isoelectric Point: 5.5981

>AT127059 WP_038906203.1 NZ_CP040817:c2418827-2418561 [Dickeya zeae]
MDINNKARIHWACRRGMRELDISIMPFFEHEYDTLSDDDKQQFIRLLQCDDPDLFNWLMNHGEPVDPGLKRMVSLIQTRN
KDRGPVAM

Download         Length: 267 bp

>AT127059 NZ_CP040817:c2418827-2418561 [Dickeya zeae]
ATGGACATCAATAACAAAGCACGTATTCACTGGGCGTGCAGGCGTGGAATGCGCGAACTGGACATCTCTATCATGCCGTT
TTTCGAGCATGAGTACGATACGCTGAGCGACGACGACAAACAGCAGTTTATTCGTCTGCTGCAGTGTGACGATCCCGACT
TGTTTAATTGGTTGATGAACCACGGTGAGCCGGTTGATCCTGGTTTGAAGCGGATGGTTTCCCTTATTCAGACGCGAAAT
AAAGATCGTGGCCCAGTGGCAATGTGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References