Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) ccdAB/CcdA(antitoxin)
Location 3096748..3097301 Replicon chromosome
Accession NZ_CP040815
Organism Dickeya zeae strain A5272

Toxin (Protein)


Gene name ccdB Uniprot ID -
Locus tag FGI00_RS13830 Protein ID WP_248587938.1
Coordinates 3096748..3097062 (-) Length 105 a.a.

Antitoxin (Protein)


Gene name ccdA Uniprot ID -
Locus tag FGI00_RS13835 Protein ID WP_038925990.1
Coordinates 3097065..3097301 (-) Length 79 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
FGI00_RS13810 (FGI00_13975) 3091841..3093079 + 1239 WP_248587935.1 IS110 family transposase -
FGI00_RS13815 (FGI00_13980) 3093128..3094954 - 1827 WP_248587936.1 hypothetical protein -
FGI00_RS13820 (FGI00_13985) 3095521..3096150 - 630 WP_248587937.1 hypothetical protein -
FGI00_RS13825 3096548..3096634 + 87 Protein_2697 mobilization protein mobC -
FGI00_RS13830 (FGI00_13995) 3096748..3097062 - 315 WP_248587938.1 CcdB family protein Toxin
FGI00_RS13835 (FGI00_14000) 3097065..3097301 - 237 WP_038925990.1 type II toxin-antitoxin system CcdA family antitoxin Antitoxin
FGI00_RS13840 (FGI00_14005) 3097622..3097939 - 318 Protein_2700 zincin-like metallopeptidase domain-containing protein -
FGI00_RS13845 (FGI00_14010) 3098023..3099345 + 1323 WP_248587601.1 IS4 family transposase -
FGI00_RS13850 (FGI00_14015) 3099356..3099997 - 642 Protein_2702 ArdC-like ssDNA-binding domain-containing protein -
FGI00_RS13855 (FGI00_14020) 3100636..3101862 - 1227 WP_248587939.1 hypothetical protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Genomic island - hcp 3078660..3122440 43780


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin CcdB

(2-103)

Antitoxin

Post-segregation antitoxin CcdA

(9-78)


Sequences

Toxin        


Download         Length: 105 a.a.        Molecular weight: 11485.42 Da        Isoelectric Point: 8.8839

>T127040 WP_248587938.1 NZ_CP040815:c3097062-3096748 [Dickeya zeae]
MQFTVYGNTGKSAVYPLLIDVTSNIIGQLNRRIVIPLLPIEKYPAGRRPDRLVPVVRLTDGKEYAVMTHELASIPVQALG
AVFCDASQYRNQVKAAIDFLIDGI

Download         Length: 315 bp

>T127040 NZ_CP040815:c3097062-3096748 [Dickeya zeae]
ATGCAATTCACCGTATACGGTAATACCGGGAAAAGCGCCGTTTACCCGCTGTTGATCGATGTTACGAGCAATATTATTGG
GCAGTTAAATCGTCGGATAGTGATCCCGTTGCTCCCTATTGAAAAGTACCCGGCAGGCCGCCGACCGGATCGCCTTGTCC
CCGTCGTCAGGCTGACGGACGGCAAAGAATACGCCGTAATGACGCACGAGCTGGCAAGTATCCCTGTGCAGGCGTTGGGT
GCGGTGTTCTGTGATGCGTCGCAGTACCGTAATCAGGTAAAAGCCGCAATAGATTTCCTCATTGACGGCATTTAA

Antitoxin


Download         Length: 79 a.a.        Molecular weight: 9090.15 Da        Isoelectric Point: 6.4629

>AT127040 WP_038925990.1 NZ_CP040815:c3097301-3097065 [Dickeya zeae]
MTAKQRNTQSVTMTVERALLVRAREAGINLSATLSTALDVELRRYEAKKWQEENREAIDALNRFHDEHGCFSDEYRTF

Download         Length: 237 bp

>AT127040 NZ_CP040815:c3097301-3097065 [Dickeya zeae]
ATGACTGCGAAACAACGCAACACGCAGAGCGTGACCATGACGGTAGAGCGTGCCTTACTGGTCCGGGCGCGTGAAGCGGG
CATTAACCTGAGTGCCACGCTGTCAACCGCACTGGATGTAGAGCTTCGCCGTTATGAGGCGAAAAAATGGCAGGAAGAGA
ACAGGGAAGCCATCGACGCATTAAATCGTTTTCATGATGAGCACGGCTGTTTCAGTGACGAATACAGGACGTTTTAA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References