Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) DhiAT/dnstrm_HI1420(antitoxin)
Location 3060778..3061528 Replicon chromosome
Accession NZ_CP040815
Organism Dickeya zeae strain A5272

Toxin (Protein)


Gene name dhiT Uniprot ID -
Locus tag FGI00_RS13670 Protein ID WP_016943626.1
Coordinates 3061271..3061528 (-) Length 86 a.a.

Antitoxin (Protein)


Gene name dhiA Uniprot ID -
Locus tag FGI00_RS13665 Protein ID WP_248587918.1
Coordinates 3060778..3061263 (-) Length 162 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
FGI00_RS13640 (FGI00_13810) 3056714..3058441 + 1728 WP_248587914.1 hydrogenase large subunit -
FGI00_RS13645 (FGI00_13815) 3058452..3059021 + 570 WP_016943631.1 hydrogenase 4 subunit H -
FGI00_RS13650 (FGI00_13820) 3059018..3059806 + 789 WP_248587915.1 NADH-quinone oxidoreductase subunit B family protein -
FGI00_RS13655 (FGI00_13825) 3059806..3060204 + 399 WP_248587916.1 formate hydrogenlyase maturation HycH family protein -
FGI00_RS13660 (FGI00_13830) 3060197..3060691 + 495 WP_248587917.1 hydrogenase maturation peptidase HycI -
FGI00_RS13665 (FGI00_13835) 3060778..3061263 - 486 WP_248587918.1 addiction module antitoxin Antitoxin
FGI00_RS13670 (FGI00_13840) 3061271..3061528 - 258 WP_016943626.1 DUF4160 domain-containing protein Toxin
FGI00_RS13675 (FGI00_13845) 3062077..3062619 + 543 WP_016943624.1 4Fe-4S dicluster domain-containing protein -
FGI00_RS13680 (FGI00_13850) 3062654..3064804 + 2151 WP_038904874.1 formate dehydrogenase subunit alpha -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Protein of unknown function DUF4160

(9-73)

Antitoxin

Uncharacterized protein HI1420

(80-156)


Sequences

Toxin        


Download         Length: 86 a.a.        Molecular weight: 9839.45 Da        Isoelectric Point: 7.5565

>T127039 WP_016943626.1 NZ_CP040815:c3061528-3061271 [Dickeya zeae]
MPEIDRLAGLIFHLYFYDDERHHLPHVHVCYGNHELIISIRTGTEIEGYLPNTKRKLAIAHIMAHREQLLSMWAQAVIGK
NPGKL

Download         Length: 258 bp

>T127039 NZ_CP040815:c3061528-3061271 [Dickeya zeae]
ATGCCTGAGATTGACAGACTGGCAGGGTTAATCTTCCATTTGTACTTTTACGATGATGAGCGGCATCACTTGCCGCATGT
GCATGTCTGCTACGGCAATCATGAACTTATCATCAGTATTCGTACCGGGACCGAGATAGAGGGATATCTGCCAAATACCA
AACGTAAGCTGGCGATTGCACATATCATGGCGCATCGTGAGCAATTGCTGAGTATGTGGGCACAGGCGGTCATCGGGAAG
AATCCGGGAAAATTGTGA

Antitoxin


Download         Length: 162 a.a.        Molecular weight: 17822.21 Da        Isoelectric Point: 6.6420

>AT127039 WP_248587918.1 NZ_CP040815:c3061263-3060778 [Dickeya zeae]
MHKIVDVDVIGDFSLRLTYDDGLIYDVNLYCYASHSVFSNASQFIRFGLLPDGSLEWPDITLSSSALREKGTYVGHTLAV
RERNFADIISRAFYDAVIENRPEILQAALKIAVDKHGNSTVAKEAGAKSRTSLYKSLNKNTNVSLATVVSLAHTVLQLEE
K

Download         Length: 486 bp

>AT127039 NZ_CP040815:c3061263-3060778 [Dickeya zeae]
ATGCATAAGATTGTGGATGTTGACGTGATTGGCGATTTTTCGTTGCGTCTGACTTATGACGATGGCCTGATATACGACGT
TAACCTGTATTGCTATGCCTCACATTCTGTGTTTTCGAATGCTAGTCAGTTTATTCGATTTGGGTTATTACCTGATGGTT
CGCTGGAATGGCCGGATATCACGCTCTCTTCGTCCGCATTACGGGAAAAGGGGACGTATGTTGGCCACACATTGGCGGTG
AGGGAGCGGAATTTTGCCGATATTATCTCCCGAGCCTTCTATGATGCCGTGATTGAGAACCGGCCAGAAATTCTGCAGGC
GGCACTGAAAATCGCAGTAGACAAACATGGCAACAGTACGGTGGCCAAAGAAGCGGGAGCCAAAAGCCGTACCAGCTTGT
ATAAATCGCTGAATAAAAACACTAATGTCAGCCTGGCGACGGTAGTTAGCCTGGCCCACACCGTGTTGCAACTAGAAGAG
AAATAA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References