Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) tsbAT/-
Location 1318279..1319052 Replicon chromosome
Accession NZ_CP040781
Organism Staphylococcus sp. 17KM0847

Toxin (Protein)


Gene name tsbT Uniprot ID -
Locus tag FGL66_RS06345 Protein ID WP_180810518.1
Coordinates 1318279..1318431 (-) Length 51 a.a.

Antitoxin (Protein)


Gene name tsbA Uniprot ID -
Locus tag FGL66_RS06350 Protein ID WP_180809037.1
Coordinates 1318453..1319052 (-) Length 200 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
FGL66_RS06330 1314489..1316015 - 1527 WP_180809034.1 exopolyphosphatase -
FGL66_RS06335 1316036..1317421 - 1386 WP_180809035.1 class II fumarate hydratase -
FGL66_RS06340 1317620..1318024 - 405 WP_180809036.1 hypothetical protein -
FGL66_RS06345 1318279..1318431 - 153 WP_180810518.1 hypothetical protein Toxin
FGL66_RS06350 1318453..1319052 - 600 WP_180809037.1 glucosamine-6-phosphate isomerase Antitoxin
FGL66_RS06355 1319076..1320254 - 1179 WP_180809038.1 N-acetylglucosamine-6-phosphate deacetylase -
FGL66_RS06360 1320276..1320746 - 471 WP_180809039.1 tRNA (uridine(34)/cytosine(34)/5- carboxymethylaminomethyluridine(34)-2'-O)- methyltransferase TrmL -
FGL66_RS06365 1320749..1321876 - 1128 WP_180810490.1 tRNA epoxyqueuosine(34) reductase QueG -
FGL66_RS06370 1322024..1322746 - 723 WP_180809040.1 amino acid ABC transporter ATP-binding protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin


No domain identified.


Antitoxin

Glucosamine-6-phosphate isomerase

(131-197)


Sequences

Toxin        


Download         Length: 51 a.a.        Molecular weight: 5949.41 Da        Isoelectric Point: 4.1048

>T126958 WP_180810518.1 NZ_CP040781:c1318431-1318279 [Staphylococcus sp. 17KM0847]
MLEKKEHDNEMVESFDDVVELGKEMEQISEANDEEKYDQSHKEIKPNTHD

Download         Length: 153 bp

>T126958 NZ_CP040781:c1318431-1318279 [Staphylococcus sp. 17KM0847]
ATGTTAGAGAAAAAAGAACATGACAATGAAATGGTAGAAAGCTTTGATGATGTTGTAGAGCTTGGAAAAGAGATGGAACA
AATCTCAGAAGCAAATGACGAAGAAAAATATGACCAATCGCATAAAGAGATTAAACCAAACACCCATGATTAA

Antitoxin


Download         Length: 200 a.a.        Molecular weight: 22325.51 Da        Isoelectric Point: 6.7653

>AT126958 WP_180809037.1 NZ_CP040781:c1319052-1318453 [Staphylococcus sp. 17KM0847]
MAMNFKIFKDQETAATFAADILRKQFNNNPTTIAGVHLSHELAPVLETLQKNVEANAVDFSQIHILDYDKQASYYKKLGV
PEKQIHEVSEDNDVEAFISRHAKTKNNKGKLTLQVISINQQGEIGLPMKESVLPAREIILVITGSKKADVVRKLYEENGS
TTFIPSALKEHRMVNVVLDEAAAQGLPKDVREYFTQLYA

Download         Length: 600 bp

>AT126958 NZ_CP040781:c1319052-1318453 [Staphylococcus sp. 17KM0847]
ATGGCAATGAATTTTAAGATTTTTAAAGATCAAGAAACTGCAGCAACATTTGCAGCAGATATTTTGAGAAAACAATTCAA
CAATAATCCTACAACAATTGCGGGGGTTCATTTGTCACACGAATTAGCACCTGTTTTAGAAACATTACAAAAAAATGTAG
AAGCGAATGCAGTAGATTTTAGTCAAATTCATATTTTAGATTATGATAAACAAGCATCTTATTATAAAAAATTAGGTGTG
CCTGAAAAACAAATACATGAAGTTTCTGAAGACAATGACGTAGAGGCATTTATTAGTCGTCATGCAAAGACTAAAAATAA
CAAAGGAAAATTAACGCTTCAAGTGATTTCGATTAATCAACAAGGTGAAATAGGTCTTCCAATGAAAGAGAGTGTATTAC
CGGCACGTGAAATTATTTTAGTGATTACAGGTAGCAAAAAAGCAGATGTAGTGCGTAAATTGTATGAAGAGAATGGCAGC
ACAACTTTTATACCATCAGCACTAAAAGAACATCGTATGGTTAATGTTGTATTGGATGAAGCAGCTGCACAAGGATTACC
AAAAGATGTTAGGGAATATTTCACACAACTTTATGCCTAA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References