126954

Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type IV Classification (family/domain) abiEi-abiEii/AbiEii-AbiEi
Location 947965..949432 Replicon chromosome
Accession NZ_CP040777
Organism Mycoplasmopsis bovis strain NADC72

Toxin (Protein)


Gene name abiEi Uniprot ID Q932V7
Locus tag FG868_RS04150 Protein ID WP_041309184.1
Coordinates 947965..948825 (-) Length 287 a.a.

Antitoxin (Protein)


Gene name abiEii Uniprot ID Q934C3
Locus tag FG868_RS04155 Protein ID WP_013456322.1
Coordinates 948818..949432 (-) Length 205 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
FG868_RS04120 (FG868_04070) 942970..943194 + 225 WP_041309186.1 hypothetical protein -
FG868_RS04125 (FG868_04075) 943586..944224 - 639 WP_235125609.1 IS30 family transposase -
FG868_RS04130 944329..944511 - 183 WP_235125612.1 helix-turn-helix domain-containing protein -
FG868_RS04135 (FG868_04080) 944889..945917 + 1029 WP_214479821.1 IS30-like element ISMbov1 family transposase -
FG868_RS04500 946172..946306 + 135 WP_255762779.1 hypothetical protein -
FG868_RS04140 946299..947024 - 726 WP_013456472.1 variable surface lipoprotein -
FG868_RS04145 (FG868_04095) 947200..947844 - 645 WP_214479814.1 variable surface lipoprotein -
FG868_RS04150 (FG868_04100) 947965..948825 - 861 WP_041309184.1 nucleotidyl transferase AbiEii/AbiGii toxin family protein Toxin
FG868_RS04155 (FG868_04105) 948818..949432 - 615 WP_013456322.1 type IV toxin-antitoxin system AbiEi family antitoxin domain-containing protein Antitoxin
FG868_RS04160 (FG868_04110) 949614..950261 + 648 WP_214479815.1 variable surface lipoprotein -
FG868_RS04165 (FG868_04115) 950382..950957 - 576 WP_075271397.1 variable surface lipoprotein -
FG868_RS04170 951173..951328 + 156 WP_180370284.1 hypothetical protein -
FG868_RS04175 (FG868_04120) 951541..952953 - 1413 WP_214479816.1 IS1634-like element ISMbov2 family transposase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Nucleotidyl transferase AbiEii toxin, Type IV TA system

(33-234)

Antitoxin

Transcriptional regulator, AbiEi antitoxin

(13-59)


Sequences

Toxin        


Download         Length: 287 a.a.        Molecular weight: 33281.35 Da        Isoelectric Point: 7.2878

>T126954 WP_041309184.1 NZ_CP040777:c948825-947965 [Mycoplasmopsis bovis]
MNKNKLISLCHKTADENNANFNVVLIQYFMESILRRISKSNERDNFVFKGGFLLSNIMGLDKRATMDIDLELIKTQKISA
SKILEKFKSILNADDIDGIRYHILKYTDIRKEHKYSGINISVLCQIENIKQVISIDIASGDVITPKEIVYEYKSIFSNQD
FSILAYNIETMLSEKLETIFSFGHLNTRFKDFYDVYVIYTFKKKDIDINRLKDACYNTFKNRNSEFNIQQLLELITNIAF
NPLMNERKKYISQIANQQEIDFKAITNSIIELLELIKVNELTNND

Download         Length: 861 bp

>T126954 NZ_CP040777:c948825-947965 [Mycoplasmopsis bovis]
ATGAATAAAAATAAATTAATAAGTTTGTGTCATAAAACTGCTGATGAAAATAACGCAAATTTCAATGTTGTTTTAATTCA
ATATTTTATGGAAAGCATTCTACGAAGAATATCTAAAAGTAATGAGAGAGACAATTTTGTGTTCAAGGGCGGTTTTCTTT
TATCTAACATTATGGGGTTAGATAAAAGAGCTACAATGGATATTGATTTGGAGCTAATAAAAACTCAAAAGATAAGTGCT
TCTAAAATATTAGAAAAATTTAAAAGTATATTAAACGCTGATGACATCGATGGAATTAGATATCACATTCTTAAGTATAC
TGACATTCGAAAGGAGCATAAATATAGTGGCATTAACATATCAGTCCTATGTCAAATAGAGAATATAAAACAAGTTATTT
CTATAGATATTGCATCAGGCGATGTCATTACACCTAAGGAAATTGTTTATGAATACAAAAGTATATTTTCAAATCAGGAT
TTTTCTATTTTAGCTTATAACATTGAAACTATGCTATCTGAAAAGCTTGAGACAATATTTTCTTTTGGTCACTTAAATAC
AAGATTTAAAGATTTTTATGATGTTTATGTTATATACACTTTTAAAAAGAAGGACATTGATATTAATAGGCTCAAGGATG
CTTGCTATAACACATTCAAAAATAGGAACAGTGAATTTAACATACAACAATTGTTGGAACTAATTACCAATATTGCTTTC
AATCCGTTGATGAATGAAAGATGAAAAAAGTACATAAGTCAGATAGCAAATCAGCAGGAAATAGACTTTAAAGCCATTAC
TAATTCAATAATAGAACTACTAGAACTAATTAAGGTCAATGAATTAACAAATAATGATTAA

Antitoxin


Download         Length: 205 a.a.        Molecular weight: 24143.83 Da        Isoelectric Point: 9.7617

>AT126954 WP_013456322.1 NZ_CP040777:c949432-948818 [Mycoplasmopsis bovis]
MEQKNLNSKYYNAIFKLLHKNNGVITYKQLKENNISSIYLTRMITKGVLIRRAKGIYILSDGHYDEYYFLSKNYKSLIFS
HYSALYLNNIIDIFPHQIDVTVYSGYNAKGIKKHANVYYCDRNKHSIGLSESKTLFGNKVKVYDFERTICDFVKLRKKTD
SEIFSKLISAYIKYENRDKKLYEYAYELGIHKKISEIFELFYE

Download         Length: 615 bp

>AT126954 NZ_CP040777:c949432-948818 [Mycoplasmopsis bovis]
ATGGAACAAAAAAACTTAAATTCGAAATATTACAATGCAATTTTTAAACTGTTACATAAAAATAACGGTGTTATCACATA
TAAGCAACTAAAAGAAAACAATATATCTTCTATATATTTAACAAGAATGATAACAAAAGGCGTTCTTATTAGAAGAGCTA
AAGGCATTTATATTCTTAGTGATGGACATTACGATGAATATTATTTCTTAAGCAAAAACTATAAATCGTTAATCTTTTCT
CATTATAGTGCACTATATTTAAATAATATTATTGACATTTTTCCGCATCAAATTGACGTTACAGTTTACAGTGGCTATAA
TGCAAAAGGCATTAAGAAGCATGCAAATGTTTACTACTGTGATAGGAATAAACATTCAATTGGACTATCTGAATCAAAAA
CATTATTTGGAAACAAAGTTAAGGTATATGACTTTGAGAGAACAATTTGTGATTTTGTAAAACTACGCAAGAAAACAGAT
AGCGAAATCTTTTCTAAGCTTATTAGTGCATATATTAAATATGAAAATAGAGATTGAAAAAAATTGTATGAATACGCCTA
TGAATTAGGCATACACAAAAAAATATCGGAGATATTTGAACTATTTTATGAATAA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB Q932V7

Antitoxin

Source ID Structure
AlphaFold DB Q934C3

References