Detailed information of TA system TA126948

Bioinformatically predicted

Overview

TA module

• Type: II
• Classification (family/domain): relBE/ParE-DnaT
• Location: 111617..112139
• Replicon: plasmid unnamed6
• Accession: NZ_CP040760
• Organism: Paracoccus liaowanqingii strain 2251

Toxin (Protein)

• Gene name: relE
• Uniprot ID: -
• Locus tag: E4191_RS17305
• Protein ID: WP_139615716.1
• Coordinates: 111617..111901 (-)
• Length: 95 a.a.

Antitoxin (Protein)

• Gene name: relB
• Uniprot ID: -
• Locus tag: E4191_RS17310
• Protein ID: WP_139615717.1
• Coordinates: 111891..112139 (-)
• Length: 83 a.a.

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
E4191_RS17285	107218..108549	+	1332	WP_139615715.1	hypothetical protein	-
E4191_RS17290	108643..108843	+	201	Protein_94	transposase	-
E4191_RS17295	108845..109066	+	222	Protein_95	transposase domain-containing protein	-
E4191_RS17300	109263..110837	-	1575	WP_139615763.1	FAD/NAD(P)-binding protein	-
E4191_RS17305	111617..111901	-	285	WP_139615716.1	type II toxin-antitoxin system RelE/ParE family toxin	Toxin
E4191_RS17310	111891..112139	-	249	WP_139615717.1	plasmid stabilization protein	Antitoxin
E4191_RS17315	112404..113525	-	1122	WP_139615718.1	hypothetical protein	-
E4191_RS17320	114072..114875	+	804	WP_139615719.1	SDR family oxidoreductase	-
E4191_RS17325	115189..115587	-	399	WP_139615720.1	response regulator	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)
	-	inside	Non-Mobilizable plasmid	-	-	1..170285	170285

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

• Toxin-antitoxin system, RelE/ParE toxin family (7-84)

Antitoxin

No domain identified.

Sequences

Toxin

Protein

• Length: 95 a.a.
• Molecular weight: 10900.82 Da
• Isoelectric Point: 10.9186

>T126948 WP_139615716.1 NZ_CP040760:c111901-111617 [Paracoccus liaowanqingii]
MSYKLSFKIEARKEWEALGAPVREQFKKVLAKRLEEPHVPSSRLSGSQVRYKIKLRSVGFRLVYEVRDDVLVVVVIAVGK
RDKNTVYRKAAERP

Nucleotide

• Length: 285 bp

>T126948 NZ_CP040760:c111901-111617 [Paracoccus liaowanqingii]
ATGAGCTATAAGCTCTCCTTCAAAATCGAGGCACGCAAGGAATGGGAGGCGCTTGGCGCCCCGGTTCGTGAGCAGTTCAA
GAAAGTCCTCGCCAAGCGGCTTGAGGAGCCGCATGTCCCCTCATCCCGGCTCTCAGGCTCCCAAGTTCGCTACAAGATCA
AGTTGCGCAGCGTAGGCTTTCGGCTCGTCTACGAAGTTCGTGATGACGTGTTGGTTGTGGTGGTCATCGCTGTTGGCAAA
CGCGACAAGAACACCGTTTACAGGAAGGCTGCAGAGCGCCCTTGA

Antitoxin

Protein

• Length: 83 a.a.
• Molecular weight: 8555.73 Da
• Isoelectric Point: 4.2989

>AT126948 WP_139615717.1 NZ_CP040760:c112139-111891 [Paracoccus liaowanqingii]
MAYMIHAGVTASVTELRRDPMGTIAAGHGGAVAILNRNAPAFYCVPAAEYEAMLTAIEDAELHALADARAASPEITVSLD
EL

Nucleotide

• Length: 249 bp

>AT126948 NZ_CP040760:c112139-111891 [Paracoccus liaowanqingii]
ATGGCTTATATGATCCATGCCGGGGTGACGGCCAGTGTCACCGAACTCAGACGCGACCCCATGGGCACGATCGCAGCCGG
CCATGGCGGTGCAGTCGCCATTCTGAACCGCAATGCGCCAGCTTTTTATTGCGTACCGGCGGCGGAATACGAGGCCATGC
TCACAGCGATTGAGGATGCTGAGTTGCATGCCCTTGCAGATGCCCGCGCGGCCAGTCCAGAAATTACGGTGTCTCTGGAT
GAGCTATAA