Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) mazEF/PemK(toxin)
Location 1812594..1813264 Replicon chromosome
Accession NZ_CP040750
Organism Plantibacter sp. M259

Toxin (Protein)


Gene name mazF Uniprot ID -
Locus tag FGL15_RS08380 Protein ID WP_138945688.1
Coordinates 1812594..1812941 (-) Length 116 a.a.

Antitoxin (Protein)


Gene name mazE Uniprot ID -
Locus tag FGL15_RS08385 Protein ID WP_205858713.1
Coordinates 1812935..1813264 (-) Length 110 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
FGL15_RS08360 1808394..1808954 + 561 WP_079003723.1 Lrp/AsnC family transcriptional regulator -
FGL15_RS08365 1808988..1809371 - 384 WP_205858712.1 hypothetical protein -
FGL15_RS08370 1809553..1810965 + 1413 WP_138945687.1 aminopeptidase P N-terminal domain-containing protein -
FGL15_RS08375 1811095..1812572 + 1478 Protein_1669 SulP family inorganic anion transporter -
FGL15_RS08380 1812594..1812941 - 348 WP_138945688.1 type II toxin-antitoxin system PemK/MazF family toxin Toxin
FGL15_RS08385 1812935..1813264 - 330 WP_205858713.1 ribbon-helix-helix protein, CopG family Antitoxin
FGL15_RS08390 1813394..1814479 + 1086 WP_137242962.1 NYN domain-containing protein -
FGL15_RS08395 1814571..1815854 - 1284 WP_138945689.1 M18 family aminopeptidase -
FGL15_RS08400 1815960..1817282 + 1323 WP_138947250.1 LssY C-terminal domain-containing protein -
FGL15_RS08405 1817279..1817776 + 498 WP_138945690.1 DUF2809 domain-containing protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

mRNA interferase PemK-like

(4-112)

Antitoxin

Ribbon-helix-helix protein, CopG

(29-63)


Sequences

Toxin        


Download         Length: 116 a.a.        Molecular weight: 12292.19 Da        Isoelectric Point: 10.3632

>T126943 WP_138945688.1 NZ_CP040750:c1812941-1812594 [Plantibacter sp. M259]
MVIRRGDIRWVDLGPRERGSAPAARRPVVVVQHDAYTRSALRTVIVAVVTSNTALAELPGNVFLPATASGLPKDSVVNTT
QLLTLDEHDLGPAAGRVPVTLSLDLDAGLRRVLHL

Download         Length: 348 bp

>T126943 NZ_CP040750:c1812941-1812594 [Plantibacter sp. M259]
TTGGTGATCCGCCGCGGTGACATCCGGTGGGTCGATCTCGGCCCTCGCGAACGGGGGAGTGCGCCCGCCGCTCGGCGCCC
GGTCGTCGTCGTCCAACATGACGCCTACACGCGGAGCGCACTCCGGACCGTGATCGTCGCGGTCGTCACGTCGAACACGG
CGCTCGCCGAGCTCCCGGGCAACGTGTTCCTCCCTGCGACGGCTTCCGGCCTGCCGAAGGACTCGGTCGTGAACACCACG
CAGCTGCTCACCCTCGATGAGCACGACCTCGGTCCGGCCGCCGGAAGGGTGCCCGTCACCCTGTCACTGGATCTGGACGC
GGGGCTCCGGCGAGTGCTGCACCTCTGA

Antitoxin


Download         Length: 110 a.a.        Molecular weight: 11427.73 Da        Isoelectric Point: 4.2904

>AT126943 WP_205858713.1 NZ_CP040750:c1813264-1812935 [Plantibacter sp. M259]
MPSHAVDIFSPGSQPELYPVILSLVKTAISLPDELFTRVEARAAELGVNRSEFFAAAASRYLDETDAAGLTAAVDTALRH
AGVASAEEARGVAAAGRDRLAELTAGDDW

Download         Length: 330 bp

>AT126943 NZ_CP040750:c1813264-1812935 [Plantibacter sp. M259]
ATGCCCAGTCACGCCGTCGACATCTTCAGCCCAGGGTCGCAACCCGAGTTATACCCGGTTATACTCTCACTCGTGAAGAC
CGCCATCTCGTTGCCTGATGAACTGTTCACCCGCGTCGAGGCTCGCGCCGCCGAGCTCGGTGTCAACCGGTCCGAGTTCT
TCGCGGCGGCGGCGAGTCGGTATCTCGACGAGACCGATGCCGCCGGTCTCACTGCCGCAGTGGACACCGCGCTGCGGCAT
GCGGGAGTCGCTTCGGCGGAGGAAGCACGGGGCGTCGCCGCGGCCGGACGCGACCGCCTTGCCGAACTCACTGCCGGAGA
CGATTGGTGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References