Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) tacAT/DUF1778(antitoxin)
Location 1765430..1766226 Replicon chromosome
Accession NZ_CP040750
Organism Plantibacter sp. M259

Toxin (Protein)


Gene name tacT Uniprot ID -
Locus tag FGL15_RS08165 Protein ID WP_138945662.1
Coordinates 1765726..1766226 (+) Length 167 a.a.

Antitoxin (Protein)


Gene name tacA Uniprot ID -
Locus tag FGL15_RS08160 Protein ID WP_138945661.1
Coordinates 1765430..1765729 (+) Length 100 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
FGL15_RS08150 1760537..1761628 + 1092 WP_138945659.1 5'-nucleotidase -
FGL15_RS08155 1761625..1764804 + 3180 WP_138945660.1 type I restriction endonuclease subunit R -
FGL15_RS08160 1765430..1765729 + 300 WP_138945661.1 DUF1778 domain-containing protein Antitoxin
FGL15_RS08165 1765726..1766226 + 501 WP_138945662.1 GNAT family N-acetyltransferase Toxin
FGL15_RS08170 1766195..1767451 - 1257 WP_138945663.1 hypothetical protein -
FGL15_RS08175 1768320..1769699 - 1380 WP_064295655.1 replicative DNA helicase -
FGL15_RS08180 1770269..1770721 - 453 WP_056780635.1 50S ribosomal protein L9 -
FGL15_RS08185 1770734..1770997 - 264 WP_056010351.1 30S ribosomal protein S18 -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Genomic island - - 1750868..1767436 16568


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

GNAT domain

(42-142)

Antitoxin

Vibrio phage ICP1, Orf50

(11-96)


Sequences

Toxin        


Download         Length: 167 a.a.        Molecular weight: 18488.98 Da        Isoelectric Point: 7.0511

>T126942 WP_138945662.1 NZ_CP040750:1765726-1766226 [Plantibacter sp. M259]
VTGFTAPRKLEKNDVRDGFNSGANELDDWFVRFAWENQAANNATTYIAHSGDRIVGFYSITMAAVSREEAPSRIAERRPS
QIPCILLARLAVDESFKGHGLGWGLLRDALIRAFQISGSIGAASVLIHCRDDTAKSFYLHHGEFLQSPVDDLHLMIPMKA
LRRFAE

Download         Length: 501 bp

>T126942 NZ_CP040750:1765726-1766226 [Plantibacter sp. M259]
GTGACAGGCTTTACCGCCCCTCGGAAACTCGAAAAGAACGATGTTCGAGACGGCTTTAATAGCGGGGCTAACGAGCTCGA
CGATTGGTTCGTCCGCTTTGCCTGGGAAAACCAGGCAGCCAACAATGCAACGACCTACATCGCGCACAGCGGTGATCGAA
TTGTGGGATTTTACTCGATCACCATGGCAGCAGTTTCTCGCGAAGAGGCGCCATCTCGAATCGCGGAGCGGCGCCCATCC
CAGATTCCGTGCATCCTGCTCGCGCGACTCGCAGTTGACGAGAGCTTCAAAGGGCATGGTCTCGGGTGGGGGTTGCTCCG
CGATGCGCTCATCAGAGCATTTCAGATCAGTGGGAGCATCGGAGCCGCATCGGTCCTAATCCACTGCCGAGATGATACAG
CTAAGAGTTTCTATCTCCACCACGGCGAGTTTCTCCAGTCACCAGTCGATGATTTGCATCTCATGATCCCTATGAAGGCA
CTTCGTCGGTTTGCGGAGTGA

Antitoxin


Download         Length: 100 a.a.        Molecular weight: 11430.82 Da        Isoelectric Point: 5.2172

>AT126942 WP_138945661.1 NZ_CP040750:1765430-1765729 [Plantibacter sp. M259]
MSESAVDTRLAKNQRINLRATGRQETLLRRAAEATDHTLTEFILGSAVEHAERVMADRRWFIATEEQFEEFNRLLDTPMP
STTKFERLFARPSVFSDEA

Download         Length: 300 bp

>AT126942 NZ_CP040750:1765430-1765729 [Plantibacter sp. M259]
ATGTCTGAATCCGCAGTCGACACTCGTCTTGCTAAAAATCAAAGAATCAACCTGCGCGCCACCGGCCGCCAGGAAACACT
GCTCCGCCGCGCTGCAGAGGCGACGGACCACACGCTCACCGAGTTTATACTCGGGAGCGCTGTTGAGCATGCGGAGCGAG
TGATGGCTGATCGTCGTTGGTTCATCGCAACCGAGGAGCAGTTTGAGGAGTTCAACCGGCTTCTCGATACACCCATGCCC
TCGACTACAAAGTTCGAGAGATTGTTTGCCCGCCCGTCTGTATTCTCGGATGAGGCGTGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References