Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type II Classification (family/domain) vapBC/PIN(toxin)
Location 1486342..1487030 Replicon chromosome
Accession NZ_CP040750
Organism Plantibacter sp. M259

Toxin (Protein)


Gene name vapC Uniprot ID -
Locus tag FGL15_RS06795 Protein ID WP_138945468.1
Coordinates 1486584..1487030 (+) Length 149 a.a.

Antitoxin (Protein)


Gene name vapB Uniprot ID -
Locus tag FGL15_RS06790 Protein ID WP_138945467.1
Coordinates 1486342..1486587 (+) Length 82 a.a.

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
FGL15_RS06770 1482608..1483276 + 669 WP_138945463.1 GntR family transcriptional regulator -
FGL15_RS06775 1483397..1484359 - 963 WP_138945464.1 prephenate dehydratase -
FGL15_RS06785 1485041..1486216 + 1176 WP_168223341.1 hypothetical protein -
FGL15_RS06790 1486342..1486587 + 246 WP_138945467.1 ribbon-helix-helix protein, CopG family Antitoxin
FGL15_RS06795 1486584..1487030 + 447 WP_138945468.1 PIN domain-containing protein Toxin
FGL15_RS06800 1487059..1488678 + 1620 WP_138945469.1 phosphoglucomutase (alpha-D-glucose-1,6-bisphosphate-dependent) -
FGL15_RS06805 1488723..1489493 - 771 WP_138947221.1 M15 family metallopeptidase -
FGL15_RS06810 1489656..1490750 + 1095 WP_138945470.1 alpha/beta hydrolase -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains


Predicted by InterproScan

Toxin

(3-142)

Antitoxin

(2-38)


Sequences


Toxin        


Download         Length: 149 a.a.        Molecular weight: 16169.31 Da        Isoelectric Point: 5.1787

>T126941 WP_138945468.1 NZ_CP040750:1486584-1487030 [Plantibacter sp. M259]
VKVPDVNVLVGAFRDDDPNHLALVRWLESAVAADEPLGVSDSVLAAYVRIVTNRRIFDPPTPLLQALESADDLRRADGVR
PVHPGPSFWRLFVRLCQESGVAGPQVADAAHAALAIEHRATFVTLDRDFARFPDLRWESPLATGQAPS

Download         Length: 447 bp

>T126941 NZ_CP040750:1486584-1487030 [Plantibacter sp. M259]
GTGAAGGTTCCGGACGTCAACGTCCTCGTGGGCGCCTTCCGGGACGACGATCCGAATCACCTCGCCCTCGTCCGCTGGCT
CGAATCCGCGGTGGCCGCCGACGAACCACTCGGCGTCAGCGACAGCGTGCTGGCCGCATACGTCAGGATCGTCACGAATC
GTCGGATCTTCGATCCGCCGACGCCGCTCCTGCAAGCACTCGAATCCGCGGACGACCTCCGGCGTGCAGACGGCGTACGA
CCGGTCCATCCGGGCCCATCGTTCTGGAGGCTCTTCGTCCGGTTGTGCCAGGAGTCCGGTGTCGCCGGACCTCAGGTCGC
CGACGCAGCCCACGCCGCGCTCGCGATCGAACACCGGGCGACCTTCGTGACGCTCGATCGCGACTTCGCGCGCTTCCCGG
ATCTCCGGTGGGAATCGCCACTCGCCACGGGTCAAGCGCCTTCCTGA

Antitoxin


Download         Length: 82 a.a.        Molecular weight: 8999.15 Da        Isoelectric Point: 5.1186

>AT126941 WP_138945467.1 NZ_CP040750:1486342-1486587 [Plantibacter sp. M259]
MRTTIRLADEFYEAVREHASQEGKTVTAYIEEALRAKLAAAATPPEREPYKVVPFRGGRGPRPGIDLTNNAQLQDIMDGL
E

Download         Length: 246 bp

>AT126941 NZ_CP040750:1486342-1486587 [Plantibacter sp. M259]
ATGCGAACGACCATCCGACTCGCCGACGAGTTCTACGAGGCCGTCCGCGAGCACGCCTCGCAGGAGGGGAAGACCGTGAC
CGCCTACATCGAAGAGGCCCTGCGCGCGAAGCTGGCCGCTGCGGCCACACCGCCCGAGCGGGAGCCGTACAAGGTCGTCC
CGTTCCGCGGCGGGCGCGGGCCTCGGCCAGGCATCGATCTGACGAACAACGCGCAGCTGCAGGACATCATGGACGGACTC
GAGTGA

Similar Proteins


Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures


Toxin

Source ID Structure


Antitoxin

Source ID Structure

References