Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) PumA-relB/upstrm_HI1419-dnstrm_HI1420
Location 2780352..2780939 Replicon chromosome
Accession NZ_CP040749
Organism Aureibaculum algae strain 10Alg 115

Toxin (Protein)


Gene name PumA Uniprot ID -
Locus tag FF125_RS11610 Protein ID WP_138949919.1
Coordinates 2780352..2780651 (+) Length 100 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID -
Locus tag FF125_RS11615 Protein ID WP_138949920.1
Coordinates 2780655..2780939 (+) Length 95 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
FF125_RS11590 (FF125_11590) 2775720..2776049 + 330 WP_138949917.1 antibiotic biosynthesis monooxygenase -
FF125_RS11595 (FF125_11595) 2776158..2777753 - 1596 WP_250629571.1 IS1182 family transposase -
FF125_RS11600 (FF125_11600) 2778003..2778995 - 993 WP_138948287.1 IS110 family transposase -
FF125_RS11605 (FF125_11605) 2779309..2780058 + 750 WP_138949918.1 YoaP domain-containing protein -
FF125_RS11610 (FF125_11610) 2780352..2780651 + 300 WP_138949919.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
FF125_RS11615 (FF125_11615) 2780655..2780939 + 285 WP_138949920.1 putative addiction module antidote protein Antitoxin
FF125_RS11620 (FF125_11620) 2781078..2781644 + 567 WP_250629572.1 Crp/Fnr family transcriptional regulator -
FF125_RS11625 (FF125_11625) 2781717..2782166 + 450 WP_138949921.1 SRPBCC family protein -
FF125_RS11630 (FF125_11630) 2782422..2782892 + 471 WP_138949922.1 DinB family protein -
FF125_RS11635 (FF125_11635) 2783115..2784623 + 1509 WP_138948275.1 IS1182 family transposase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Addiction module killer protein, predicted

(4-96)

Antitoxin

Uncharacterized protein HI1420

(3-89)


Sequences

Toxin        


Download         Length: 100 a.a.        Molecular weight: 11734.86 Da        Isoelectric Point: 10.4596

>T126940 WP_138949919.1 NZ_CP040749:2780352-2780651 [Aureibaculum algae]
MFFIEKTTEFDKWLKKLKDFKAKAKILFRIQKLETDEHFGDCKTVGDGIREMRINFAKGYRVYFKEKDGKVIVLLIGGDK
STQQKDITKAKEIWKKLNK

Download         Length: 300 bp

>T126940 NZ_CP040749:2780352-2780651 [Aureibaculum algae]
ATGTTCTTTATTGAGAAAACAACCGAATTTGACAAATGGCTGAAAAAGTTAAAAGACTTTAAGGCAAAAGCAAAGATTTT
GTTCAGAATTCAAAAATTAGAAACAGACGAACATTTTGGAGATTGTAAAACAGTTGGAGATGGAATTCGTGAAATGCGAA
TAAATTTTGCTAAAGGCTACAGAGTTTATTTCAAAGAAAAAGACGGAAAAGTAATTGTCCTTCTGATTGGCGGAGATAAA
TCAACTCAACAAAAAGACATTACGAAAGCGAAAGAAATTTGGAAAAAATTAAATAAATAG

Antitoxin


Download         Length: 95 a.a.        Molecular weight: 10154.70 Da        Isoelectric Point: 5.8254

>AT126940 WP_138949920.1 NZ_CP040749:2780655-2780939 [Aureibaculum algae]
MGTSRFEIADYLENKEMIAEYLNTVLEEGNNADIINAIGHIAKAIGMTKIAEETGLSRPSLYKSLSEGAKPQFATIMKVL
KAIGGQIQVNPKSA

Download         Length: 285 bp

>AT126940 NZ_CP040749:2780655-2780939 [Aureibaculum algae]
ATGGGAACTTCAAGATTTGAAATAGCGGATTATTTGGAAAATAAAGAAATGATTGCGGAATACCTAAATACAGTTTTGGA
AGAAGGTAATAACGCGGATATAATTAATGCAATCGGACACATAGCAAAAGCAATCGGAATGACAAAAATTGCGGAGGAAA
CTGGTTTGAGCAGACCGAGTTTGTACAAATCATTATCAGAAGGAGCGAAACCCCAATTTGCTACAATTATGAAAGTTTTG
AAAGCAATAGGTGGACAAATCCAAGTGAATCCTAAGTCCGCATAA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References