Detailed information of TA system TA126929

Bioinformatically predicted

Overview

TA module

• Type: II
• Classification (family/domain): relE-yefM/YoeB-RelB
• Location: 1302697..1303231
• Replicon: chromosome
• Accession: NZ_CP040736
• Organism: Companilactobacillus futsaii strain Y97

Toxin (Protein)

• Gene name: relE
• Uniprot ID: -
• Locus tag: FG051_RS06420
• Protein ID: WP_057814812.1
• Coordinates: 1302697..1302960 (-)
• Length: 88 a.a.

Antitoxin (Protein)

• Gene name: yefM
• Uniprot ID: -
• Locus tag: FG051_RS06425
• Protein ID: WP_057814815.1
• Coordinates: 1302950..1303231 (-)
• Length: 94 a.a.

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
FG051_RS06385	1298540..1298803	+	264	WP_162256560.1	type II toxin-antitoxin system Phd/YefM family antitoxin	-
FG051_RS06390	1298945..1299976	+	1032	WP_149029771.1	IS30 family transposase	-
FG051_RS06395	1300050..1300313	+	264	WP_083484618.1	Txe/YoeB family addiction module toxin	-
FG051_RS06400	1300729..1300935	+	207	WP_057814809.1	hypothetical protein	-
FG051_RS06405	1301030..1301296	+	267	WP_083484619.1	AbrB/MazE/SpoVT family DNA-binding domain-containing protein	-
FG051_RS06410	1301307..1301651	+	345	WP_083484620.1	type II toxin-antitoxin system PemK/MazF family toxin	-
FG051_RS06415	1301926..1302640	+	715	Protein_1267	EamA family transporter	-
FG051_RS06420	1302697..1302960	-	264	WP_057814812.1	Txe/YoeB family addiction module toxin	Toxin
FG051_RS06425	1302950..1303231	-	282	WP_057814815.1	type II toxin-antitoxin system prevent-host-death family antitoxin	Antitoxin
FG051_RS06430	1303657..1303899	+	243	WP_057814817.1	ATP-binding cassette domain-containing protein	-
FG051_RS06435	1303785..1304126	+	342	WP_083484623.1	hypothetical protein	-
FG051_RS06440	1304636..1304836	+	201	WP_057814819.1	hypothetical protein	-
FG051_RS06445	1304906..1305148	+	243	Protein_1273	capsid protein	-
FG051_RS06450	1305181..1306233	-	1053	Protein_1274	amidohydrolase	-
FG051_RS06455	1306239..1306832	+	594	WP_083484621.1	acetyltransferase	-
FG051_RS06460	1306829..1307182	-	354	WP_057814821.1	NAD(P)H-binding protein	-
FG051_RS06465	1307203..1307364	-	162	WP_187323348.1	hypothetical protein	-
FG051_RS06470	1307673..1307906	+	234	WP_057814823.1	hypothetical protein	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

• Toxin YoeB (6-87)

Antitoxin

• Type II toxin-antitoxin system, antitoxin Phd/YefM (5-76)

Sequences

Toxin

Protein

• Length: 88 a.a.
• Molecular weight: 10561.32 Da
• Isoelectric Point: 10.3195

>T126929 WP_057814812.1 NZ_CP040736:c1302960-1302697 [Companilactobacillus futsaii]
MKIDRVSFTIKALSDYQYWQKQDRKTLKILNRIINDIIRHPFTGIGKPEPLKYKLDNCWSRRINKSDRIVYTVTNDSIII
IQCRYHY

Nucleotide

• Length: 264 bp

>T126929 NZ_CP040736:c1302960-1302697 [Companilactobacillus futsaii]
ATGAAAATTGATCGAGTAAGTTTTACCATTAAGGCTTTGTCAGATTATCAATATTGGCAAAAACAAGACCGAAAAACTTT
AAAGATTCTAAATCGGATAATTAATGATATTATTCGACATCCCTTTACGGGTATAGGTAAACCGGAACCTTTAAAATACA
AATTAGACAATTGCTGGTCCAGAAGAATTAATAAAAGCGACCGAATCGTCTATACGGTTACAAATGATTCAATCATTATC
ATTCAATGTCGCTATCATTACTAA

Antitoxin

Protein

• Length: 94 a.a.
• Molecular weight: 10846.17 Da
• Isoelectric Point: 5.2170

>AT126929 WP_057814815.1 NZ_CP040736:c1303231-1302950 [Companilactobacillus futsaii]
MATTATNISEARKNLKKLTDDVVDYDDHVIITKPKNRNVVIMSEKEYQSWKETMYLLGTEANRKNLDESLEQLNRGNLKT
ISKEEWDKLSNEN

Nucleotide

• Length: 282 bp

>AT126929 NZ_CP040736:c1303231-1302950 [Companilactobacillus futsaii]
ATGGCAACTACCGCAACTAACATTTCTGAAGCAAGAAAGAATTTAAAAAAATTAACTGACGACGTAGTTGATTATGATGA
TCATGTAATAATTACGAAGCCAAAAAATCGTAATGTGGTTATTATGTCGGAAAAAGAATATCAATCTTGGAAAGAAACCA
TGTACCTACTCGGCACAGAAGCAAATCGTAAAAATTTGGATGAATCTTTAGAGCAACTAAACAGAGGTAACCTAAAGACA
ATATCAAAAGAAGAATGGGATAAACTTTCTAATGAAAATTGA