Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relE-yefM/YoeB-YefM
Location 5073167..5073666 Replicon chromosome
Accession NZ_CP040719
Organism Rhodococcus pyridinivorans strain YF3

Toxin (Protein)


Gene name relE Uniprot ID V9XF56
Locus tag FGO65_RS23500 Protein ID WP_024102500.1
Coordinates 5073167..5073421 (-) Length 85 a.a.

Antitoxin (Protein)


Gene name yefM Uniprot ID H0JMW3
Locus tag FGO65_RS23505 Protein ID WP_006550855.1
Coordinates 5073418..5073666 (-) Length 83 a.a.

Genomic Context

FGO65_RS23475FGO65_RS28625FGO65_RS23510FGO65_RS23515FGO65_RS23520FGO65_RS23470FGO65_RS23480FGO65_RS23485FGO65_RS23490FGO65_RS23500FGO65_RS23505
Location: 5069874..5070500 (627 bp)
Type: Others
Protein ID: WP_006550849.1
Location: 5072545..5073066 (522 bp)
Type: Others
Protein ID: WP_175428047.1
Location: 5073702..5074031 (330 bp)
Type: Others
Protein ID: WP_138845192.1
Location: 5074498..5075292 (795 bp)
Type: Others
Protein ID: WP_138845193.1
Location: 5075353..5076603 (1251 bp)
Type: Others
Protein ID: WP_138845195.1
Location: 5068602..5069771 (1170 bp)
Type: Others
Protein ID: WP_064256074.1
Location: 5070658..5070870 (213 bp)
Type: Others
Protein ID: WP_024102496.1
Location: 5070877..5071065 (189 bp)
Type: Others
Protein ID: WP_138845190.1
Location: 5071432..5072388 (957 bp)
Type: Others
Protein ID: WP_019290518.1
Location: 5073167..5073421 (255 bp)
Type: Toxin
Protein ID: WP_024102500.1
Location: 5073418..5073666 (249 bp)
Type: Antitoxin
Protein ID: WP_006550855.1
ToxinAntitoxinOther genes
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Locus tag
Coordinates
Strand
Size (bp)
Protein ID
Product
Description
FGO65_RS234705068602..5069771-1170WP_064256074.1acyl-CoA dehydrogenase family protein-
FGO65_RS234755069874..5070500+627WP_006550849.1TetR family transcriptional regulator-
FGO65_RS234805070658..5070870-213WP_024102496.1transposase-
FGO65_RS234855070877..5071065-189WP_138845190.1hypothetical protein-
FGO65_RS234905071432..5072388-957WP_019290518.1Lsr2 family protein-
FGO65_RS286255072545..5073066+522WP_175428047.1hypothetical protein-
FGO65_RS235005073167..5073421-255WP_024102500.1Txe/YoeB family addiction module toxinToxin
FGO65_RS235055073418..5073666-249WP_006550855.1type II toxin-antitoxin system prevent-host-death family antitoxinAntitoxin
FGO65_RS235105073702..5074031+330WP_138845192.1hypothetical protein-
FGO65_RS235155074498..5075292+795WP_138845193.1LLM class F420-dependent oxidoreductase-
FGO65_RS235205075353..5076603+1251WP_138845195.1alpha/beta fold hydrolase-

Associated MGEs

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MGE
detail
Similar
MGEs
Relative
position
MGE Type
Cargo ARG
Virulence gene
Coordinates
Length (bp)
No matching records found


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin YoeB

(2-84)

Antitoxin

Type II toxin-antitoxin system, antitoxin Phd/YefM

(1-70)


Sequences

Toxin        


Download         Length: 85 a.a.        Molecular weight: 10077.42 Da        Isoelectric Point: 8.0410

>T126900 WP_024102500.1 NZ_CP040719:c5073421-5073167 [Rhodococcus pyridinivorans]
VNITFTDEAWDDYQFWISTDRKQLKRVNELIRDCQRDPYSGIGKPERLRHALSGLWSRRIDKEHRLVYEVIDGALVIIAA
RYHY

Download         Length: 255 bp

>T126900 NZ_CP040719:c5073421-5073167 [Rhodococcus pyridinivorans]
GTGAACATCACCTTCACCGACGAAGCCTGGGACGACTACCAGTTCTGGATCTCGACCGACAGAAAACAGCTCAAGCGTGT
CAACGAGCTGATCAGGGATTGCCAACGAGACCCGTACTCGGGGATCGGCAAACCCGAACGGCTCAGACATGCCCTGTCAG
GACTGTGGTCTCGACGTATCGACAAAGAACACCGCCTGGTCTACGAGGTCATCGACGGTGCCCTGGTCATCATCGCCGCC
CGCTACCACTACTGA

Antitoxin


Download         Length: 83 a.a.        Molecular weight: 9290.59 Da        Isoelectric Point: 5.8315

>AT126900 WP_006550855.1 NZ_CP040719:c5073666-5073418 [Rhodococcus pyridinivorans]
MAAITATEARKNFFPLLEQVNKDHTPVEIVSKRGNAVLMSKDDYDAMLETSYLMQSPANARRLLASMQRARGGEYTEREL
IE

Download         Length: 249 bp

>AT126900 NZ_CP040719:c5073666-5073418 [Rhodococcus pyridinivorans]
ATGGCTGCCATCACTGCTACCGAAGCGAGAAAAAACTTCTTTCCGCTGCTCGAACAGGTCAACAAGGACCACACCCCTGT
GGAAATCGTATCCAAGCGGGGCAATGCCGTCCTGATGTCGAAGGATGACTACGACGCCATGCTCGAGACCTCGTACCTGA
TGCAGTCTCCGGCCAACGCCCGACGACTGCTCGCCAGCATGCAGAGAGCTCGCGGAGGTGAATACACCGAAAGGGAACTC
ATCGAGTGA

Similar Proteins

Only experimentally validated proteins are listed.

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Protein
Organism
Identities (%)
Coverage (%)
Ha-value
No matching records found
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Protein
Organism
Identities (%)
Coverage (%)
Ha-value
No matching records found

Structures

Toxin

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Source
ID
Structure
AlphaFold DBA0A7M2XPP3

Antitoxin

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Source
ID
Structure
AlphaFold DBH0JMW3

References