Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) mazEF/MazF(toxin)
Location 4854678..4855219 Replicon chromosome
Accession NZ_CP040719
Organism Rhodococcus pyridinivorans strain YF3

Toxin (Protein)


Gene name mazF Uniprot ID -
Locus tag FGO65_RS22375 Protein ID WP_138845823.1
Coordinates 4854678..4854977 (-) Length 100 a.a.

Antitoxin (Protein)


Gene name mazE Uniprot ID -
Locus tag FGO65_RS22380 Protein ID WP_138844995.1
Coordinates 4854977..4855219 (-) Length 81 a.a.

Genomic Context

FGO65_RS22345FGO65_RS22350FGO65_RS22365FGO65_RS22370FGO65_RS22385FGO65_RS22395FGO65_RS22400FGO65_RS22355FGO65_RS22360FGO65_RS22375FGO65_RS22380FGO65_RS22390
Location: 4850332..4851147 (816 bp)
Type: Others
Protein ID: WP_138844991.1
Location: 4851305..4852045 (741 bp)
Type: Others
Protein ID: WP_138844993.1
Location: 4853614..4853910 (297 bp)
Type: Others
Protein ID: Protein_4393
Location: 4853932..4854300 (369 bp)
Type: Others
Protein ID: WP_138845821.1
Location: 4855663..4856577 (915 bp)
Type: Others
Protein ID: WP_138844997.1
Location: 4857904..4858419 (516 bp)
Type: Others
Protein ID: WP_138845825.1
Location: 4858911..4859714 (804 bp)
Type: Others
Protein ID: WP_006941794.1
Location: 4852313..4852673 (361 bp)
Type: Others
Protein ID: Protein_4391
Location: 4852776..4853618 (843 bp)
Type: Others
Protein ID: Protein_4392
Location: 4854678..4854977 (300 bp)
Type: Toxin
Protein ID: WP_138845823.1
Location: 4854977..4855219 (243 bp)
Type: Antitoxin
Protein ID: WP_138844995.1
Location: 4857178..4857729 (552 bp)
Type: Others
Protein ID: WP_138844999.1
ToxinAntitoxinOther genes
Loading, please wait
Locus tag
Coordinates
Strand
Size (bp)
Protein ID
Product
Description
FGO65_RS223454850332..4851147+816WP_138844991.1SDR family oxidoreductase-
FGO65_RS223504851305..4852045+741WP_138844993.1FadR family transcriptional regulator-
FGO65_RS223554852313..4852673-361Protein_4391protein kinase-
FGO65_RS223604852776..4853618-843Protein_4392hypothetical protein-
FGO65_RS223654853614..4853910+297Protein_4393hypothetical protein-
FGO65_RS223704853932..4854300+369WP_138845821.1dihydrofolate reductase family protein-
FGO65_RS223754854678..4854977-300WP_138845823.1type II toxin-antitoxin system PemK/MazF family toxinToxin
FGO65_RS223804854977..4855219-243WP_138844995.1antitoxinAntitoxin
FGO65_RS223854855663..4856577+915WP_138844997.1LLM class flavin-dependent oxidoreductase-
FGO65_RS223904857178..4857729-552WP_138844999.1TetR/AcrR family transcriptional regulator-
FGO65_RS223954857904..4858419+516WP_138845825.1thioesterase family protein-
FGO65_RS224004858911..4859714+804WP_006941794.1enoyl-CoA hydratase/isomerase family protein-

Associated MGEs

Loading, please wait
MGE
detail
Similar
MGEs
Relative
position
MGE Type
Cargo ARG
Virulence gene
Coordinates
Length (bp)
No matching records found


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

mRNA interferase PemK-like

(3-98)

Antitoxin


No domain identified.



Sequences

Toxin        


Download         Length: 100 a.a.        Molecular weight: 10529.25 Da        Isoelectric Point: 8.0583

>T126899 WP_138845823.1 NZ_CP040719:c4854977-4854678 [Rhodococcus pyridinivorans]
MRPIHAAKLDKTRPVLVLTRELVRPHLGRVTVAPITGTVRGLSTEVPVGPANGLEKDSVVSCDNIVTIPVSALGRSLGFF
FPAQEAALSEAIRAAFDLE

Download         Length: 300 bp

>T126899 NZ_CP040719:c4854977-4854678 [Rhodococcus pyridinivorans]
ATGCGGCCGATTCACGCCGCGAAGCTGGACAAGACGCGGCCGGTGTTGGTGTTGACCCGCGAGTTGGTGCGTCCGCACCT
GGGCAGGGTGACGGTGGCGCCGATCACCGGCACCGTGCGGGGGTTGTCGACAGAGGTGCCGGTGGGCCCGGCGAACGGAT
TGGAGAAGGATTCGGTGGTCAGTTGCGACAACATCGTCACCATTCCGGTGTCGGCGTTGGGGCGCAGTCTCGGGTTTTTC
TTTCCGGCGCAGGAAGCGGCGCTGTCCGAGGCGATTCGGGCCGCGTTCGACCTCGAATGA

Antitoxin


Download         Length: 81 a.a.        Molecular weight: 9031.14 Da        Isoelectric Point: 4.9060

>AT126899 WP_138844995.1 NZ_CP040719:c4855219-4854977 [Rhodococcus pyridinivorans]
MSTQIAVRLPDEIVAFVDEEVREHRAPSRAALVLRALERERRRRIAARDVEILSRARGEADPDEFDGLARYAAGLSSDLE

Download         Length: 243 bp

>AT126899 NZ_CP040719:c4855219-4854977 [Rhodococcus pyridinivorans]
ATGAGTACGCAGATTGCGGTGCGCTTGCCGGATGAGATTGTGGCTTTCGTCGATGAGGAGGTGCGGGAGCATCGGGCTCC
CAGTCGTGCGGCGCTGGTGTTGCGGGCGCTCGAACGGGAGCGGCGTCGGCGGATCGCCGCCCGCGATGTCGAGATTCTGT
CCCGGGCTCGCGGTGAAGCGGATCCGGACGAGTTCGATGGGCTCGCACGATATGCCGCAGGCCTGTCGAGCGATCTCGAA
TGA

Similar Proteins

Only experimentally validated proteins are listed.

Loading, please wait
Protein
Organism
Identities (%)
Coverage (%)
Ha-value
No matching records found
Loading, please wait
Protein
Organism
Identities (%)
Coverage (%)
Ha-value
No matching records found

Structures

Toxin

Loading, please wait
Source
ID
Structure
No matching records found

Antitoxin

Loading, please wait
Source
ID
Structure
No matching records found

References