Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) pezAT/zeta-ParD
Location 2610908..2611860 Replicon chromosome
Accession NZ_CP040719
Organism Rhodococcus pyridinivorans strain YF3

Toxin (Protein)


Gene name pezT Uniprot ID A0A0B1RG18
Locus tag FGO65_RS12270 Protein ID WP_019289576.1
Coordinates 2610908..2611477 (-) Length 190 a.a.

Antitoxin (Protein)


Gene name pezA Uniprot ID A0A7M2XIK8
Locus tag FGO65_RS12275 Protein ID WP_016696422.1
Coordinates 2611474..2611860 (-) Length 129 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
FGO65_RS12270 2610908..2611477 - 570 WP_019289576.1 zeta toxin family protein Toxin
FGO65_RS12275 2611474..2611860 - 387 WP_016696422.1 hypothetical protein Antitoxin
FGO65_RS12280 2612068..2613138 + 1071 WP_138843340.1 class I SAM-dependent methyltransferase -
FGO65_RS12285 2613208..2613573 + 366 WP_138843342.1 HNH endonuclease -
FGO65_RS12290 2613590..2614135 - 546 WP_138843344.1 hypothetical protein -
FGO65_RS12295 2615250..2616182 - 933 WP_138843346.1 TAXI family TRAP transporter solute-binding subunit -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Zeta toxin domain

(4-136)

Antitoxin

ParD-like antitoxin of type II bacterial toxin-antitoxin system

(7-104)


Sequences

Toxin        


Download         Length: 190 a.a.        Molecular weight: 20522.68 Da        Isoelectric Point: 10.6895

>T126898 WP_019289576.1 NZ_CP040719:c2611477-2610908 [Rhodococcus pyridinivorans]
MRRLDLIVGPNGSGKSTFVELSLAPLLPRSVFVNADVIARQRWPDRAEEMSYEAAQLAAAARDRLLRQGRSFIAETVFSH
PSKLELIDRAHEVGFTVVLHVMLVPEAMSVLRVQHRVASGGHAVPEDKIRARYRRLWPLVAEAIGRADQASVYDTASGTP
VVVARFAGGVPVGAVRWPGWAPAALTGLG

Download         Length: 570 bp

>T126898 NZ_CP040719:c2611477-2610908 [Rhodococcus pyridinivorans]
ATGAGGCGTCTGGATCTGATCGTCGGTCCCAACGGTTCCGGCAAGTCGACGTTCGTCGAGTTGTCCCTCGCTCCCCTGCT
GCCGCGCAGCGTGTTCGTCAATGCGGATGTGATCGCGCGGCAGCGCTGGCCCGACCGGGCGGAGGAGATGTCGTACGAGG
CGGCGCAGCTCGCCGCGGCGGCGCGGGACCGGTTGCTGCGGCAGGGCCGGTCGTTCATTGCGGAGACGGTGTTCTCGCAT
CCGTCGAAGCTGGAGTTGATCGACCGCGCGCACGAGGTGGGGTTCACGGTGGTGCTGCACGTGATGCTGGTGCCCGAGGC
GATGTCGGTGCTGCGTGTACAGCACCGGGTGGCCTCCGGTGGGCATGCGGTGCCCGAGGACAAGATCCGGGCGCGTTATC
GGCGGTTGTGGCCGCTGGTGGCCGAAGCGATCGGCCGCGCCGATCAGGCGTCGGTGTACGACACGGCGTCCGGGACCCCG
GTGGTGGTGGCGCGGTTCGCCGGCGGGGTGCCGGTGGGTGCGGTGCGCTGGCCGGGATGGGCGCCGGCGGCGCTCACCGG
GCTCGGCTGA

Antitoxin


Download         Length: 129 a.a.        Molecular weight: 14038.49 Da        Isoelectric Point: 4.7096

>AT126898 WP_016696422.1 NZ_CP040719:c2611860-2611474 [Rhodococcus pyridinivorans]
MTSSTDKVTRFDAELVDSAIAEGGRQNRTGRQQLEYWARIGRAMTAHETASLHRVHEALAGTRELSELTAAEGRLFDAEI
DARLADGLARTDYAEVLAARGVTTVVLDDEGRLVEQRPDGSRRVLDDA

Download         Length: 387 bp

>AT126898 NZ_CP040719:c2611860-2611474 [Rhodococcus pyridinivorans]
ATGACGTCATCCACCGACAAGGTCACCCGCTTCGACGCCGAACTCGTCGACAGCGCCATCGCCGAGGGTGGCCGCCAGAA
CCGCACCGGACGCCAGCAACTCGAATACTGGGCCCGCATCGGCCGCGCGATGACCGCCCACGAGACCGCCTCCCTGCACC
GGGTGCACGAGGCGCTGGCCGGGACACGGGAGCTGAGCGAGCTCACCGCCGCCGAGGGACGGCTGTTCGACGCGGAGATC
GATGCGCGCCTGGCGGACGGGCTGGCCCGCACCGACTACGCCGAGGTTCTCGCCGCGCGTGGGGTCACCACGGTGGTGCT
CGACGACGAAGGCCGGCTGGTCGAGCAGCGTCCCGACGGTAGTCGCCGGGTGCTCGACGACGCATGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A0B1RG18

Antitoxin

Source ID Structure
AlphaFold DB A0A7M2XIK8

References