Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relBE/RelE-Phd
Location 558196..558761 Replicon chromosome
Accession NZ_CP040719
Organism Rhodococcus pyridinivorans strain YF3

Toxin (Protein)


Gene name relE Uniprot ID -
Locus tag FGO65_RS02745 Protein ID WP_175427899.1
Coordinates 558483..558761 (+) Length 93 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID -
Locus tag FGO65_RS02740 Protein ID WP_006551856.1
Coordinates 558196..558486 (+) Length 97 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
FGO65_RS02715 553429..554031 + 603 WP_138845417.1 TetR/AcrR family transcriptional regulator -
FGO65_RS02720 554028..554456 + 429 WP_019290063.1 HIT family protein -
FGO65_RS02725 554461..556062 + 1602 WP_138841656.1 L-lactate permease -
FGO65_RS02730 556139..557167 + 1029 WP_064255975.1 Dyp-type peroxidase -
FGO65_RS02735 557164..557982 + 819 WP_006551857.1 bacteriocin family protein -
FGO65_RS02740 558196..558486 + 291 WP_006551856.1 type II toxin-antitoxin system Phd/YefM family antitoxin Antitoxin
FGO65_RS02745 558483..558761 + 279 WP_175427899.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
FGO65_RS02750 558818..559129 - 312 WP_138841658.1 hypothetical protein -
FGO65_RS02755 559188..559937 - 750 WP_024102983.1 cutinase family protein -
FGO65_RS02760 560087..560749 - 663 WP_138841660.1 alpha-ketoglutarate-dependent dioxygenase AlkB -
FGO65_RS02765 560870..561700 + 831 WP_006551851.1 SDR family oxidoreductase -
FGO65_RS02770 561745..562716 + 972 WP_138841662.1 phosphotriesterase -
FGO65_RS02775 562753..563472 - 720 WP_138841664.1 2OG-Fe(II) oxygenase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(21-91)

Antitoxin

Type II toxin-antitoxin system, antitoxin Phd/YefM

(3-73)


Sequences

Toxin        


Download         Length: 93 a.a.        Molecular weight: 10282.89 Da        Isoelectric Point: 10.3570

>T126897 WP_175427899.1 NZ_CP040719:558483-558761 [Rhodococcus pyridinivorans]
MSTPDHPYRLVMARSAARAMARSLPEKVATAVYEFVTGPLLEKPKRVGKPLNPPLAPAYSARRGEYRVLYLIDDANRTVE
VTAISHRADAYR

Download         Length: 279 bp

>T126897 NZ_CP040719:558483-558761 [Rhodococcus pyridinivorans]
ATGAGCACTCCGGACCACCCGTATCGGCTGGTGATGGCGAGGTCGGCTGCACGCGCCATGGCGAGGTCGTTGCCGGAGAA
GGTAGCAACTGCGGTATACGAGTTCGTCACAGGACCCCTTCTCGAGAAGCCGAAGCGGGTGGGGAAGCCGTTGAATCCGC
CTCTTGCGCCGGCGTACAGCGCCCGGCGAGGTGAATATCGCGTCCTGTATCTGATCGATGATGCGAACCGCACGGTCGAG
GTCACCGCGATTTCGCACCGTGCCGATGCGTATCGATAG

Antitoxin


Download         Length: 97 a.a.        Molecular weight: 10788.92 Da        Isoelectric Point: 4.2336

>AT126897 WP_006551856.1 NZ_CP040719:558196-558486 [Rhodococcus pyridinivorans]
MYMTTLPVADARAQLSRLVDEAERTHERFEITRNGHRAAVLLGADDYDAMQETIAVLSDTDLLRAHVEGRTEVESGDVVD
VQELTQLMRDARSSEE

Download         Length: 291 bp

>AT126897 NZ_CP040719:558196-558486 [Rhodococcus pyridinivorans]
ATGTACATGACGACTCTTCCTGTTGCCGACGCGCGGGCGCAATTGTCACGACTGGTCGATGAGGCCGAGCGCACACACGA
GCGATTCGAGATCACCCGCAACGGGCACCGCGCCGCGGTGCTTCTCGGTGCCGACGATTACGACGCGATGCAGGAGACGA
TCGCGGTGTTGTCGGATACGGATCTGCTGCGGGCGCACGTCGAGGGCCGAACGGAGGTCGAGTCGGGGGACGTCGTCGAT
GTACAGGAATTGACGCAGCTGATGCGTGATGCTCGGTCGTCCGAGGAATGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References