Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relBE/RelE-Phd
Location 558196..558761 Replicon chromosome
Accession NZ_CP040719
Organism Rhodococcus pyridinivorans strain YF3

Toxin (Protein)


Gene name relE Uniprot ID -
Locus tag FGO65_RS02745 Protein ID WP_175427899.1
Coordinates 558483..558761 (+) Length 93 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID -
Locus tag FGO65_RS02740 Protein ID WP_006551856.1
Coordinates 558196..558486 (+) Length 97 a.a.

Genomic Context

FGO65_RS02715FGO65_RS02720FGO65_RS02725FGO65_RS02730FGO65_RS02735FGO65_RS02740FGO65_RS02745FGO65_RS02765FGO65_RS02770FGO65_RS02750FGO65_RS02755FGO65_RS02760FGO65_RS02775
Location: 553429..554031 (603 bp)
Type: Others
Protein ID: WP_138845417.1
Location: 554028..554456 (429 bp)
Type: Others
Protein ID: WP_019290063.1
Location: 554461..556062 (1602 bp)
Type: Others
Protein ID: WP_138841656.1
Location: 556139..557167 (1029 bp)
Type: Others
Protein ID: WP_064255975.1
Location: 557164..557982 (819 bp)
Type: Others
Protein ID: WP_006551857.1
Location: 558196..558486 (291 bp)
Type: Antitoxin
Protein ID: WP_006551856.1
Location: 558483..558761 (279 bp)
Type: Toxin
Protein ID: WP_175427899.1
Location: 560870..561700 (831 bp)
Type: Others
Protein ID: WP_006551851.1
Location: 561745..562716 (972 bp)
Type: Others
Protein ID: WP_138841662.1
Location: 558818..559129 (312 bp)
Type: Others
Protein ID: WP_138841658.1
Location: 559188..559937 (750 bp)
Type: Others
Protein ID: WP_024102983.1
Location: 560087..560749 (663 bp)
Type: Others
Protein ID: WP_138841660.1
Location: 562753..563472 (720 bp)
Type: Others
Protein ID: WP_138841664.1
ToxinAntitoxinOther genes
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Locus tag
Coordinates
Strand
Size (bp)
Protein ID
Product
Description
FGO65_RS02715553429..554031+603WP_138845417.1TetR/AcrR family transcriptional regulator-
FGO65_RS02720554028..554456+429WP_019290063.1HIT family protein-
FGO65_RS02725554461..556062+1602WP_138841656.1L-lactate permease-
FGO65_RS02730556139..557167+1029WP_064255975.1Dyp-type peroxidase-
FGO65_RS02735557164..557982+819WP_006551857.1bacteriocin family protein-
FGO65_RS02740558196..558486+291WP_006551856.1type II toxin-antitoxin system Phd/YefM family antitoxinAntitoxin
FGO65_RS02745558483..558761+279WP_175427899.1type II toxin-antitoxin system RelE/ParE family toxinToxin
FGO65_RS02750558818..559129-312WP_138841658.1hypothetical protein-
FGO65_RS02755559188..559937-750WP_024102983.1cutinase family protein-
FGO65_RS02760560087..560749-663WP_138841660.1alpha-ketoglutarate-dependent dioxygenase AlkB-
FGO65_RS02765560870..561700+831WP_006551851.1SDR family oxidoreductase-
FGO65_RS02770561745..562716+972WP_138841662.1phosphotriesterase-
FGO65_RS02775562753..563472-720WP_138841664.12OG-Fe(II) oxygenase-

Associated MGEs

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MGE
detail
Similar
MGEs
Relative
position
MGE Type
Cargo ARG
Virulence gene
Coordinates
Length (bp)
No matching records found


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(21-91)

Antitoxin

Type II toxin-antitoxin system, antitoxin Phd/YefM

(3-73)


Sequences

Toxin        


Download         Length: 93 a.a.        Molecular weight: 10282.89 Da        Isoelectric Point: 10.3570

>T126897 WP_175427899.1 NZ_CP040719:558483-558761 [Rhodococcus pyridinivorans]
MSTPDHPYRLVMARSAARAMARSLPEKVATAVYEFVTGPLLEKPKRVGKPLNPPLAPAYSARRGEYRVLYLIDDANRTVE
VTAISHRADAYR

Download         Length: 279 bp

>T126897 NZ_CP040719:558483-558761 [Rhodococcus pyridinivorans]
ATGAGCACTCCGGACCACCCGTATCGGCTGGTGATGGCGAGGTCGGCTGCACGCGCCATGGCGAGGTCGTTGCCGGAGAA
GGTAGCAACTGCGGTATACGAGTTCGTCACAGGACCCCTTCTCGAGAAGCCGAAGCGGGTGGGGAAGCCGTTGAATCCGC
CTCTTGCGCCGGCGTACAGCGCCCGGCGAGGTGAATATCGCGTCCTGTATCTGATCGATGATGCGAACCGCACGGTCGAG
GTCACCGCGATTTCGCACCGTGCCGATGCGTATCGATAG

Antitoxin


Download         Length: 97 a.a.        Molecular weight: 10788.92 Da        Isoelectric Point: 4.2336

>AT126897 WP_006551856.1 NZ_CP040719:558196-558486 [Rhodococcus pyridinivorans]
MYMTTLPVADARAQLSRLVDEAERTHERFEITRNGHRAAVLLGADDYDAMQETIAVLSDTDLLRAHVEGRTEVESGDVVD
VQELTQLMRDARSSEE

Download         Length: 291 bp

>AT126897 NZ_CP040719:558196-558486 [Rhodococcus pyridinivorans]
ATGTACATGACGACTCTTCCTGTTGCCGACGCGCGGGCGCAATTGTCACGACTGGTCGATGAGGCCGAGCGCACACACGA
GCGATTCGAGATCACCCGCAACGGGCACCGCGCCGCGGTGCTTCTCGGTGCCGACGATTACGACGCGATGCAGGAGACGA
TCGCGGTGTTGTCGGATACGGATCTGCTGCGGGCGCACGTCGAGGGCCGAACGGAGGTCGAGTCGGGGGACGTCGTCGAT
GTACAGGAATTGACGCAGCTGATGCGTGATGCTCGGTCGTCCGAGGAATGA

Similar Proteins

Only experimentally validated proteins are listed.

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Protein
Organism
Identities (%)
Coverage (%)
Ha-value
No matching records found
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Protein
Organism
Identities (%)
Coverage (%)
Ha-value
No matching records found

Structures

Toxin

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Source
ID
Structure
No matching records found

Antitoxin

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Source
ID
Structure
No matching records found

References