Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 3852350..3852495 Replicon chromosome
Accession NZ_CP040711
Organism Klebsiella pneumoniae strain 16HN-35

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 3852357..3852459 (-)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 3852350..3852495 (+)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
FGL96_RS18965 (FGL96_19030) 3847882..3849315 + 1434 WP_101345779.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -
FGL96_RS18970 (FGL96_19035) 3849431..3849670 + 240 WP_002911393.1 YebV family protein -
FGL96_RS18975 (FGL96_19040) 3849768..3849959 + 192 WP_002911395.1 YebW family protein -
FGL96_RS18980 (FGL96_19045) 3849956..3850609 - 654 WP_004180432.1 protein-serine/threonine phosphatase -
FGL96_RS18985 (FGL96_19050) 3850766..3851734 + 969 WP_004151446.1 VirK/YbjX family protein -
FGL96_RS18990 3851839..3851982 + 144 WP_002911398.1 Ecr family regulatory small membrane protein -
- 3852350..3852495 + 146 - - Antitoxin
- 3852357..3852459 - 103 - - Toxin
FGL96_RS18995 (FGL96_19060) 3852618..3852956 - 339 WP_002911404.1 YebY family protein -
FGL96_RS19000 (FGL96_19065) 3852973..3853842 - 870 WP_062955019.1 copper homeostasis membrane protein CopD -
FGL96_RS19005 (FGL96_19070) 3853846..3854220 - 375 WP_004151448.1 CopC domain-containing protein YobA -
FGL96_RS19010 (FGL96_19075) 3854333..3854563 + 231 WP_002911406.1 DNA polymerase III subunit theta -
FGL96_RS19015 (FGL96_19080) 3854642..3855301 + 660 WP_002911407.1 exodeoxyribonuclease X -
FGL96_RS19020 (FGL96_19085) 3855305..3857365 - 2061 WP_004151449.1 oligopeptidase B -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 103 bp

>T126875 NZ_CP040711:c3852459-3852357 [Klebsiella pneumoniae]
GCAAGGCGACTTAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATACA
GGAATCGTATTCGGTCTCTTTTT

Antitoxin


Download         Length: 146 bp

>AT126875 NZ_CP040711:3852350-3852495 [Klebsiella pneumoniae]
TAAAGATAAAAAGAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAG
TTGGCATTAATGCAGGCTAAGTCGCCTTGCACTATAAGAATAGTTTAACGCGTCAGCTTTTCCAGT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References