Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) PumA-relB/upstrm_HI1419-dnstrm_HI1420
Location 685056..685596 Replicon chromosome
Accession NZ_CP040710
Organism Aggregatimonas sangjinii strain F202Z8

Toxin (Protein)


Gene name PumA Uniprot ID -
Locus tag FGM00_RS02800 Protein ID WP_262711086.1
Coordinates 685342..685596 (-) Length 85 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID -
Locus tag FGM00_RS02795 Protein ID WP_138851449.1
Coordinates 685056..685340 (-) Length 95 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
FGM00_RS02775 (FGM00_02775) 680807..682297 + 1491 WP_138851446.1 potassium transporter TrkG -
FGM00_RS02780 (FGM00_02780) 682268..682714 - 447 WP_138851447.1 DUF1801 domain-containing protein -
FGM00_RS02785 (FGM00_02785) 682923..683765 - 843 WP_138851448.1 hypothetical protein -
FGM00_RS02790 (FGM00_02790) 684401..684955 - 555 WP_236262883.1 hypothetical protein -
FGM00_RS02795 (FGM00_02795) 685056..685340 - 285 WP_138851449.1 putative addiction module antidote protein Antitoxin
FGM00_RS02800 (FGM00_02800) 685342..685596 - 255 WP_262711086.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
FGM00_RS02805 (FGM00_02805) 686464..687459 - 996 WP_138851450.1 IS110 family transposase -
FGM00_RS02810 (FGM00_02810) 688054..688353 - 300 WP_138851451.1 type II toxin-antitoxin system RelE/ParE family toxin -
FGM00_RS02815 (FGM00_02815) 688346..688597 - 252 WP_138851452.1 type II toxin-antitoxin system ParD family antitoxin -
FGM00_RS02820 (FGM00_02820) 689255..689791 - 537 WP_138851453.1 DUF2199 domain-containing protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Addiction module killer protein, predicted

(1-79)

Antitoxin

Uncharacterized protein HI1420

(2-91)


Sequences

Toxin        


Download         Length: 85 a.a.        Molecular weight: 9634.23 Da        Isoelectric Point: 10.3032

>T126866 WP_262711086.1 NZ_CP040710:c685596-685342 [Aggregatimonas sangjinii]
IRDLRAKAKILFRLQKLEDSGHLGDCKSVGNGIHEMRINYAKGYRVYFKETESQIVILLIGGTKSTQKEDIKKAKKIWNG
IKDE

Download         Length: 255 bp

>T126866 NZ_CP040710:c685596-685342 [Aggregatimonas sangjinii]
ATCAGGGACCTAAGGGCGAAGGCCAAGATACTTTTCCGATTACAGAAACTCGAGGACAGCGGACACCTTGGCGACTGTAA
ATCTGTCGGTAACGGAATCCACGAAATGCGGATCAATTATGCGAAAGGCTACAGGGTCTATTTCAAGGAGACGGAAAGCC
AAATCGTGATACTTCTGATCGGAGGAACCAAATCGACCCAAAAAGAGGACATCAAAAAAGCGAAGAAAATCTGGAACGGA
ATCAAAGACGAATGA

Antitoxin


Download         Length: 95 a.a.        Molecular weight: 10024.56 Da        Isoelectric Point: 4.7205

>AT126866 WP_138851449.1 NZ_CP040710:c685340-685056 [Aggregatimonas sangjinii]
MTTTKFDIADYLDSNEMIAEYLNTTLEEGDSSDLVVAIGHIAKAIGMTKIAEETGMSRPSLYKALSDGAKPQFGTIMKVL
KAVGGQISVKPLSV

Download         Length: 285 bp

>AT126866 NZ_CP040710:c685340-685056 [Aggregatimonas sangjinii]
ATGACAACGACAAAATTCGACATAGCGGACTATTTGGACAGCAATGAAATGATAGCGGAATACCTGAACACGACACTTGA
AGAAGGCGACAGCTCGGACCTTGTGGTCGCCATCGGCCATATCGCTAAGGCGATCGGAATGACCAAAATAGCCGAGGAGA
CCGGAATGAGCCGACCGAGCCTTTACAAGGCATTGTCGGACGGTGCCAAACCACAGTTCGGGACAATAATGAAAGTGCTG
AAAGCAGTGGGAGGACAGATCAGCGTAAAACCGTTATCGGTATAA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References