Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) ccdAB/CcdA(antitoxin)
Location 81991..82516 Replicon plasmid unnamed
Accession NZ_CP040702
Organism Salmonella enterica subsp. enterica serovar Weltevreden strain 3 isolate CFSAN047349

Toxin (Protein)


Gene name ccdB Uniprot ID A0A4V6H280
Locus tag EA483_RS25000 Protein ID WP_001159862.1
Coordinates 82211..82516 (+) Length 102 a.a.

Antitoxin (Protein)


Gene name ccdA Uniprot ID A0A4U8C9U5
Locus tag EA483_RS24995 Protein ID WP_000813644.1
Coordinates 81991..82209 (+) Length 73 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
EA483_RS24985 78652..79521 - 870 Protein_61 IS5 family transposase -
EA483_RS24990 80101..81305 + 1205 WP_086011258.1 IS3 family transposase -
EA483_RS24995 81991..82209 + 219 WP_000813644.1 type II toxin-antitoxin system antitoxin CcdA Antitoxin
EA483_RS25000 82211..82516 + 306 WP_001159862.1 type II toxin-antitoxin system toxin CcdB Toxin
EA483_RS25005 82586..82711 + 126 WP_015633283.1 hypothetical protein -
EA483_RS25010 82825..83607 + 783 WP_000083588.1 site-specific integrase -
EA483_RS25015 83758..84699 - 942 WP_000728920.1 Rpn family recombination-promoting nuclease/putative transposase -
EA483_RS25020 85125..86330 + 1206 WP_000427674.1 AAA family ATPase -
EA483_RS25025 86330..87304 + 975 WP_000064273.1 ParB/RepB/Spo0J family partition protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Non-Mobilizable plasmid - - 1..104768 104768


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin


No domain identified.


Antitoxin


No domain identified.



Sequences

Toxin        


Download         Length: 102 a.a.        Molecular weight: 13091.77 Da        Isoelectric Point: 12.8043

>T126861 WP_001159862.1 NZ_CP040702:82211-82516 [Salmonella enterica subsp. enterica serovar Weltevreden]
KKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKK
KKKKKKKKKKKKKKKKKKKKKK

Download         Length: 306 bp

>T126861 NZ_CP040702:82211-82516 [Salmonella enterica subsp. enterica serovar Weltevreden]
AAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAA
AAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAA
AAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAA
AAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAA

Antitoxin


Download         Length: 73 a.a.        Molecular weight: 9374.72 Da        Isoelectric Point: 12.6573

>AT126861 WP_000813644.1 NZ_CP040702:81991-82209 [Salmonella enterica subsp. enterica serovar Weltevreden]
KKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKK

Download         Length: 219 bp

>AT126861 NZ_CP040702:81991-82209 [Salmonella enterica subsp. enterica serovar Weltevreden]
AAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAA
AAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAA
AAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A4V6H280

Antitoxin

Source ID Structure
AlphaFold DB A0A4U8C9U5

References