Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) tacT-ataR/DUF1778(antitoxin)
Location 50161..50918 Replicon plasmid unnamed
Accession NZ_CP040702
Organism Salmonella enterica subsp. enterica serovar Weltevreden strain 3 isolate CFSAN047349

Toxin (Protein)


Gene name tacT Uniprot ID A0A4U8I7M5
Locus tag EA483_RS24935 Protein ID WP_000406363.1
Coordinates 50436..50918 (+) Length 161 a.a.

Antitoxin (Protein)


Gene name ataR Uniprot ID A0A4U8I6Z6
Locus tag EA483_RS24930 Protein ID WP_001195099.1
Coordinates 50161..50445 (+) Length 95 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
EA483_RS24900 46384..47433 + 1050 WP_001534988.1 hypothetical protein -
EA483_RS24910 47836..48030 + 195 Protein_48 DUF4158 domain-containing protein -
EA483_RS24915 48367..48645 + 279 WP_000534855.1 cloacin -
EA483_RS24920 48630..49592 - 963 WP_000145248.1 hypothetical protein -
EA483_RS24925 49589..49849 - 261 WP_000929810.1 hypothetical protein -
EA483_RS24930 50161..50445 + 285 WP_001195099.1 DUF1778 domain-containing protein Antitoxin
EA483_RS24935 50436..50918 + 483 WP_000406363.1 GNAT family N-acetyltransferase Toxin
EA483_RS24945 51302..51751 + 450 WP_000750479.1 hypothetical protein -
EA483_RS24960 53118..53876 + 759 WP_000493752.1 4'-phosphopantetheinyl transferase superfamily protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Non-Mobilizable plasmid - - 1..104768 104768


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Hok/gef cell toxic protein

(8-48)

Antitoxin


No domain identified.



Sequences

Toxin        


Download         Length: 161 a.a.        Molecular weight: 20654.05 Da        Isoelectric Point: 13.0041

>T126860 WP_000406363.1 NZ_CP040702:50436-50918 [Salmonella enterica subsp. enterica serovar Weltevreden]
KKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKK
KKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKK
K

Download         Length: 483 bp

>T126860 NZ_CP040702:50436-50918 [Salmonella enterica subsp. enterica serovar Weltevreden]
AAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAA
AAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAA
AAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAA
AAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAA
AAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAA
AAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAA
AAA

Antitoxin


Download         Length: 95 a.a.        Molecular weight: 12194.55 Da        Isoelectric Point: 12.7731

>AT126860 WP_001195099.1 NZ_CP040702:50161-50445 [Salmonella enterica subsp. enterica serovar Weltevreden]
KKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKK
KKKKKKKKKKKKKKK

Download         Length: 285 bp

>AT126860 NZ_CP040702:50161-50445 [Salmonella enterica subsp. enterica serovar Weltevreden]
AAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAA
AAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAA
AAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAA
AAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A4U8I7M5

Antitoxin

Source ID Structure
AlphaFold DB A0A4U8I6Z6

References