Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relE-yefM/YoeB-RelB
Location 2259268..2259781 Replicon chromosome
Accession NZ_CP040694
Organism Elizabethkingia sp. JS20170427COW

Toxin (Protein)


Gene name relE Uniprot ID -
Locus tag FGE20_RS10155 Protein ID WP_138983386.1
Coordinates 2259268..2259525 (-) Length 86 a.a.

Antitoxin (Protein)


Gene name yefM Uniprot ID -
Locus tag FGE20_RS10160 Protein ID WP_138982954.1
Coordinates 2259527..2259781 (-) Length 85 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
FGE20_RS10130 2254983..2256615 + 1633 Protein_1960 glycoside hydrolase family 3 C-terminal domain-containing protein -
FGE20_RS10135 2256671..2257141 - 471 WP_138983385.1 nucleoside deaminase -
FGE20_RS10140 2257300..2257782 + 483 WP_138982951.1 ABC transporter ATPase -
FGE20_RS10145 2257860..2258711 - 852 WP_138982952.1 SDR family oxidoreductase -
FGE20_RS10150 2258768..2259175 - 408 WP_138982953.1 Rrf2 family transcriptional regulator -
FGE20_RS10155 2259268..2259525 - 258 WP_138983386.1 Txe/YoeB family addiction module toxin Toxin
FGE20_RS10160 2259527..2259781 - 255 WP_138982954.1 type II toxin-antitoxin system prevent-host-death family antitoxin Antitoxin
FGE20_RS10165 2259897..2260589 + 693 WP_138982955.1 DUF1826 domain-containing protein -
FGE20_RS10170 2260658..2260924 - 267 WP_138982956.1 helix-turn-helix domain-containing protein -
FGE20_RS10175 2261016..2261714 - 699 WP_138982957.1 NERD domain-containing protein -
FGE20_RS10180 2261947..2262654 - 708 WP_138982958.1 LrgB family protein -
FGE20_RS10185 2262651..2262998 - 348 WP_138982959.1 CidA/LrgA family protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin YoeB

(5-84)

Antitoxin

Type II toxin-antitoxin system, antitoxin Phd/YefM

(1-73)


Sequences

Toxin        


Download         Length: 86 a.a.        Molecular weight: 10600.21 Da        Isoelectric Point: 8.7705

>T126859 WP_138983386.1 NZ_CP040694:c2259525-2259268 [Elizabethkingia sp. JS20170427COW]
MKFIFVDESWEDYLYWQKTDKKKLKRINDLLKDISRIPYEGIGKPEPLKHKYSGFRSRRIDEEHRLIYLYQEDEILIAKC
RFHYD

Download         Length: 258 bp

>T126859 NZ_CP040694:c2259525-2259268 [Elizabethkingia sp. JS20170427COW]
ATGAAATTTATTTTTGTGGACGAATCCTGGGAAGATTACCTGTATTGGCAAAAAACCGATAAGAAAAAACTGAAACGCAT
CAATGATTTATTGAAAGATATTTCCCGGATACCTTATGAAGGTATTGGAAAACCAGAACCACTGAAACATAAATATTCCG
GATTCAGGTCCAGACGAATCGATGAAGAACATCGGCTGATTTACCTTTATCAGGAAGATGAAATCCTGATTGCCAAATGC
AGATTCCATTACGATTAA

Antitoxin


Download         Length: 85 a.a.        Molecular weight: 9535.97 Da        Isoelectric Point: 5.8700

>AT126859 WP_138982954.1 NZ_CP040694:c2259781-2259527 [Elizabethkingia sp. JS20170427COW]
MLIASVSDFRKDLKSYLDKVAKNFETLIINRGKDSGIVVMSLEEYNSLMATNHELSSRKNEMRLDAAIEKLKEGKSLSKD
LIED

Download         Length: 255 bp

>AT126859 NZ_CP040694:c2259781-2259527 [Elizabethkingia sp. JS20170427COW]
ATGTTAATTGCCAGTGTATCCGATTTCAGGAAAGATTTAAAATCCTATTTAGACAAAGTTGCCAAAAACTTTGAAACCTT
GATCATTAACCGAGGGAAAGATTCGGGAATTGTGGTGATGTCTTTGGAAGAATACAATTCTCTGATGGCGACCAATCACG
AACTTTCTTCAAGGAAAAATGAAATGCGTCTGGACGCCGCTATCGAAAAATTAAAAGAGGGAAAATCACTTTCCAAGGAT
TTAATTGAAGATTAA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References