Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) EcnAB/-
Location 4794526..4794876 Replicon chromosome
Accession NZ_CP040687
Organism Xanthomonas oryzae pv. oryzae strain IXO1088

Toxin (Protein)


Gene name EcnB Uniprot ID G7TLC7
Locus tag IXO1088_RS22410 Protein ID WP_011257368.1
Coordinates 4794526..4794660 (-) Length 45 a.a.

Antitoxin (Protein)


Gene name EcnA Uniprot ID G7TLC8
Locus tag IXO1088_RS22415 Protein ID WP_011407410.1
Coordinates 4794724..4794876 (-) Length 51 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
IXO1088_RS22395 4791540..4792562 - 1023 WP_075240574.1 MBL fold metallo-hydrolase -
IXO1088_RS22400 4792615..4793904 - 1290 WP_011257370.1 tryptophan--tRNA ligase -
IXO1088_RS22405 4794073..4794282 - 210 WP_011407411.1 CsbD family protein -
IXO1088_RS22410 4794526..4794660 - 135 WP_011257368.1 entericidin A/B family lipoprotein Toxin
IXO1088_RS22415 4794724..4794876 - 153 WP_011407410.1 entericidin A/B family lipoprotein Antitoxin
IXO1088_RS22420 4794984..4795907 - 924 WP_011407409.1 arginase -
IXO1088_RS22425 4796229..4796903 + 675 WP_011257366.1 hypothetical protein -
IXO1088_RS22430 4796900..4797139 + 240 WP_011257365.1 hypothetical protein -
IXO1088_RS22435 4797146..4797442 + 297 WP_012446308.1 hypothetical protein -
IXO1088_RS22440 4797922..4798605 + 684 WP_011257363.1 dTMP kinase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Entericidin A/B

(23-42)

Antitoxin

Entericidin A/B

(23-42)


Sequences

Toxin        


Download         Length: 45 a.a.        Molecular weight: 4457.33 Da        Isoelectric Point: 10.2040

>T126496 WP_011257368.1 NZ_CP040687:c4794660-4794526 [Xanthomonas oryzae pv. oryzae]
MKRAIVLLVLSMLSVGLLSGCNTVAGAGKDVKGAGEKVEDAARK

Download         Length: 135 bp

>T126496 NZ_CP040687:c4794660-4794526 [Xanthomonas oryzae pv. oryzae]
ATGAAGCGTGCAATTGTGCTGCTCGTGCTGTCCATGTTGTCGGTCGGTCTGCTGTCGGGCTGCAACACCGTCGCAGGTGC
CGGCAAGGACGTGAAGGGCGCCGGCGAGAAGGTGGAAGACGCAGCGCGTAAGTAA

Antitoxin


Download         Length: 51 a.a.        Molecular weight: 5046.99 Da        Isoelectric Point: 8.7942

>AT126496 WP_011407410.1 NZ_CP040687:c4794876-4794724 [Xanthomonas oryzae pv. oryzae]
MKRLLTLMVLGLFSAGVMTGCNTVAGAGKDLQGAGGKVEKTAEKCSDGKC

Download         Length: 153 bp

>AT126496 NZ_CP040687:c4794876-4794724 [Xanthomonas oryzae pv. oryzae]
ATGAAGCGACTGCTGACACTGATGGTGCTGGGCCTGTTTTCGGCCGGCGTGATGACGGGCTGCAACACCGTGGCTGGCGC
TGGCAAGGACTTGCAGGGCGCGGGTGGGAAGGTCGAGAAAACGGCCGAAAAATGCAGCGATGGTAAGTGCTGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A0C5UG40

Antitoxin

Source ID Structure
AlphaFold DB A0A0C5V759

References