Detailed information of TA system TA126494

Bioinformatically predicted

Overview

TA module

• Type: II
• Classification (family/domain): relB-parE/ParE-RHH
• Location: 2949036..2949592
• Replicon: chromosome
• Accession: NZ_CP040687
• Organism: Xanthomonas oryzae pv. oryzae strain IXO1088

Toxin (Protein)

• Gene name: parE
• Uniprot ID: -
• Locus tag: IXO1088_RS13580
• Protein ID: WP_027703932.1
• Coordinates: 2949036..2949326 (-)
• Length: 97 a.a.

Antitoxin (Protein)

• Gene name: relB
• Uniprot ID: A0A854CIX2
• Locus tag: IXO1088_RS13585
• Protein ID: WP_011408759.1
• Coordinates: 2949314..2949592 (-)
• Length: 93 a.a.

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
IXO1088_RS13535	2944806..2945897	+	1092	WP_011408756.1	ribonuclease D	-
IXO1088_RS13540	2945994..2946310	-	317	Protein_2578	ATP-dependent DNA ligase	-
IXO1088_RS13545	2946370..2946576	-	207	Protein_2579	hypothetical protein	-
IXO1088_RS13550	2946592..2946768	-	177	Protein_2580	DUF3606 domain-containing protein	-
IXO1088_RS13555	2946990..2947391	+	402	WP_011259345.1	H-NS histone family protein	-
IXO1088_RS13570	2948255..2948434	-	180	WP_015463309.1	hypothetical protein	-
IXO1088_RS24005	2948578..2948775	-	198	WP_153296741.1	hypothetical protein	-
IXO1088_RS13580	2949036..2949326	-	291	WP_027703932.1	type II toxin-antitoxin system RelE/ParE family toxin	Toxin
IXO1088_RS13585	2949314..2949592	-	279	WP_011408759.1	CopG family ribbon-helix-helix protein	Antitoxin
IXO1088_RS24010	2949673..2949876	-	204	WP_198912807.1	hypothetical protein	-
IXO1088_RS24015	2949788..2950132	-	345	WP_198912817.1	hypothetical protein	-
IXO1088_RS13595	2950077..2950277	-	201	WP_027703931.1	ribbon-helix-helix protein, CopG family	-
IXO1088_RS13600	2950527..2951483	-	957	WP_011407237.1	IS30-like element IS1112a family transposase	-
IXO1088_RS13605	2952096..2953280	-	1185	WP_011408397.1	IS256 family transposase	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

• Toxin-antitoxin system, RelE/ParE toxin family (4-94)

Antitoxin

• Ribbon-helix-helix protein, CopG (5-42)

Sequences

Toxin

Protein

• Length: 97 a.a.
• Molecular weight: 10915.48 Da
• Isoelectric Point: 9.5554

>T126494 WP_027703932.1 NZ_CP040687:c2949326-2949036 [Xanthomonas oryzae pv. oryzae]
MPQVIFAPAAIGDMLRLREFLRPKNPDAARRAGEAIRRGVQALGAHPRMGRLIEDLSEQYREWLIDFGDSGYVARYRFDG
DTVTILAVRHQKEAGY

Nucleotide

• Length: 291 bp

>T126494 NZ_CP040687:c2949326-2949036 [Xanthomonas oryzae pv. oryzae]
ATGCCACAAGTAATCTTTGCGCCGGCGGCGATCGGGGACATGCTACGGCTGCGTGAATTCCTGAGGCCGAAGAATCCCGA
TGCCGCGAGGCGGGCCGGCGAAGCGATTAGGCGCGGCGTCCAGGCTCTCGGTGCCCACCCTCGAATGGGGCGGCTCATAG
AAGATCTGTCTGAACAGTATCGGGAGTGGCTTATCGATTTTGGGGATAGCGGCTATGTGGCTCGGTACCGCTTCGATGGG
GATACCGTCACGATTTTGGCCGTGCGACACCAGAAGGAAGCGGGGTACTGA

Antitoxin

Protein

• Length: 93 a.a.
• Molecular weight: 10826.11 Da
• Isoelectric Point: 4.9736

>AT126494 WP_011408759.1 NZ_CP040687:c2949592-2949314 [Xanthomonas oryzae pv. oryzae]
MVTATSIKLDDELKGRVQHLAESRRRTPHWIMREAIEQYVEREEKREALNRDTLKAWDEFQATGLHVTAEEVDKWLASWG
TDDELPPPECHK

Nucleotide

• Length: 279 bp

>AT126494 NZ_CP040687:c2949592-2949314 [Xanthomonas oryzae pv. oryzae]
ATGGTTACGGCAACTTCCATCAAGCTTGATGATGAATTGAAAGGGCGGGTTCAGCACTTGGCAGAGTCGCGCCGGCGTAC
CCCGCATTGGATCATGCGCGAAGCCATTGAGCAGTACGTCGAGCGCGAGGAAAAGCGCGAGGCGCTGAACCGGGACACGC
TCAAGGCATGGGATGAATTTCAGGCGACTGGCCTGCATGTGACCGCTGAGGAAGTGGACAAGTGGCTCGCGAGCTGGGGA
ACTGACGACGAACTGCCTCCGCCAGAATGCCACAAGTAA

Structures

Antitoxin

• AlphaFold DB: A0A854CIX2