Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type IV Classification (family/domain) cptAB/Cpta(toxin)
Location 814843..815506 Replicon chromosome
Accession NZ_CP040677
Organism Kosakonia sacchari strain DSM 107661

Toxin (Protein)


Gene name cptA Uniprot ID -
Locus tag FGE25_RS03945 Protein ID WP_020455134.1
Coordinates 815090..815506 (+) Length 139 a.a.

Antitoxin (Protein)


Gene name cptB Uniprot ID -
Locus tag FGE25_RS03940 Protein ID WP_020455135.1
Coordinates 814843..815109 (+) Length 89 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
FGE25_RS03920 810375..811808 - 1434 WP_045512790.1 6-phospho-beta-glucosidase -
FGE25_RS03925 811925..812653 - 729 WP_045512787.1 MurR/RpiR family transcriptional regulator -
FGE25_RS03930 812891..813550 + 660 WP_020455137.1 hemolysin III family protein -
FGE25_RS03935 813613..814596 - 984 WP_160268745.1 tRNA-modifying protein YgfZ -
FGE25_RS03940 814843..815109 + 267 WP_020455135.1 FAD assembly factor SdhE Antitoxin
FGE25_RS03945 815090..815506 + 417 WP_020455134.1 protein YgfX Toxin
FGE25_RS03950 815520..816041 - 522 WP_020455133.1 flavodoxin FldB -
FGE25_RS03955 816141..817037 + 897 WP_097406125.1 site-specific tyrosine recombinase XerD -
FGE25_RS03960 817062..817772 + 711 WP_020455131.1 bifunctional protein-disulfide isomerase/oxidoreductase DsbC -
FGE25_RS03965 817778..819511 + 1734 WP_045512778.1 single-stranded-DNA-specific exonuclease RecJ -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Inner membrane protein YgfX

(3-131)

Antitoxin

Flavinator of succinate dehydrogenase

(7-79)


Sequences

Toxin        


Download         Length: 139 a.a.        Molecular weight: 16360.26 Da        Isoelectric Point: 11.0079

>T126471 WP_020455134.1 NZ_CP040677:815090-815506 [Kosakonia sacchari]
VVLWQSDLRVSWRAQWISLLLHGLVAAFILFMPWPLSYTPLWLLLLSLVVFDCVRSQRRINACHGEIKLLMDSRLRWQGV
EWDIVGTPWMIRGGMMLRLRRAEDGRRQHLWLAADSMDSQEWRDLRRMITQNPAQGLH

Download         Length: 417 bp

>T126471 NZ_CP040677:815090-815506 [Kosakonia sacchari]
GTGGTCCTGTGGCAATCTGATTTACGCGTCTCATGGCGCGCACAATGGATTTCGTTATTACTGCACGGGCTGGTGGCGGC
GTTCATTCTTTTTATGCCCTGGCCGTTGAGCTATACGCCGCTGTGGCTTTTGCTGCTGTCGCTGGTGGTTTTCGACTGTG
TGCGCAGCCAGCGGCGGATCAACGCCTGCCATGGCGAGATCAAATTGCTGATGGATTCCCGCCTGCGCTGGCAAGGTGTG
GAGTGGGATATTGTCGGTACGCCCTGGATGATCCGCGGTGGCATGATGTTGCGTTTACGCCGTGCGGAAGATGGGCGGCG
CCAGCATTTATGGCTGGCGGCAGACAGTATGGATTCGCAGGAGTGGCGCGATCTACGCCGGATGATCACCCAAAATCCGG
CGCAGGGGCTGCATTAA

Antitoxin


Download         Length: 89 a.a.        Molecular weight: 10544.99 Da        Isoelectric Point: 6.3238

>AT126471 WP_020455135.1 NZ_CP040677:814843-815109 [Kosakonia sacchari]
MDINNKARIHWACRRGMRELDISIMPFFEHEYDSLSDHDKHLFVRLLESDDPDLFNWLMNHGKPQDAELQRMVQLIQTRN
RDRGPVAI

Download         Length: 267 bp

>AT126471 NZ_CP040677:814843-815109 [Kosakonia sacchari]
ATGGATATTAATAATAAAGCCCGTATCCATTGGGCCTGTCGCCGCGGAATGCGCGAACTCGATATCTCCATCATGCCTTT
TTTCGAACACGAGTACGACTCGCTCAGCGATCATGACAAGCACCTGTTTGTGCGTCTGCTGGAGAGTGATGATCCGGATT
TATTCAACTGGTTGATGAATCATGGCAAACCCCAGGACGCGGAGTTGCAGCGAATGGTGCAGTTAATTCAGACACGGAAT
CGGGATCGTGGTCCTGTGGCAATCTGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References