Detailed information of TA system TA126467

Bioinformatically predicted

Overview

TA module

• Type: II
• Classification (family/domain): vapBC/VapC-VagC
• Location: 17983..18608
• Replicon: plasmid SA20082869 strain 14[5]12:i:-
• Accession: NZ_CP040669
• Organism: Salmonella enterica subsp. enterica serovar 14[5]12:i:- strain SA20082869

Toxin (Protein)

• Gene name: vapC
• Uniprot ID: -
• Locus tag: FGO77_RS24355
• Protein ID: WP_000911322.1
• Coordinates: 17983..18381 (-)
• Length: 133 a.a.

Antitoxin (Protein)

• Gene name: vapB
• Uniprot ID: -
• Locus tag: FGO77_RS24360
• Protein ID: WP_000450265.1
• Coordinates: 18381..18608 (-)
• Length: 76 a.a.

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
FGO77_RS24340	14093..14587	+	495	WP_010999946.1	entry exclusion protein	-
FGO77_RS24345	14623..15354	+	732	WP_022743186.1	complement resistance protein TraT	-
FGO77_RS24350	15731..17974	+	2244	WP_031608981.1	type IV conjugative transfer system coupling protein TraD	-
FGO77_RS24355	17983..18381	-	399	WP_000911322.1	tRNA(fMet)-specific endonuclease VapC	Toxin
FGO77_RS24360	18381..18608	-	228	WP_000450265.1	toxin-antitoxin system antitoxin VapB	Antitoxin

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)
	-	inside	Non-Mobilizable plasmid	-	-	1..107560	107560

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

• PIN domain (3-124)

Antitoxin

• SpoVT-AbrB domain (7-42)

Sequences

Toxin

Protein

• Length: 133 a.a.
• Molecular weight: 19592.50 Da
• Isoelectric Point: 5.5500

>T126467 WP_000911322.1 NZ_CP040669:c18381-17983 [Salmonella enterica subsp. enterica serovar 1,4,[5],12:i:-]
FFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFF
FFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFF

Nucleotide

• Length: 399 bp

>T126467 NZ_CP040669:c18381-17983 [Salmonella enterica subsp. enterica serovar 1,4,[5],12:i:-]
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Antitoxin

Protein

• Length: 76 a.a.
• Molecular weight: 11203.44 Da
• Isoelectric Point: 5.5500

>AT126467 WP_000450265.1 NZ_CP040669:c18608-18381 [Salmonella enterica subsp. enterica serovar 1,4,[5],12:i:-]
FFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFF

Nucleotide

• Length: 228 bp

>AT126467 NZ_CP040669:c18608-18381 [Salmonella enterica subsp. enterica serovar 1,4,[5],12:i:-]
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