Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 1491196..1491467 Replicon chromosome
Accession NZ_CP040667
Organism Escherichia coli strain S17-1

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 1491326..1491429 (+)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 1491196..1491467 (-)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
FGH86_RS07100 1487751..1488413 - 663 WP_000944256.1 exodeoxyribonuclease X -
FGH86_RS07105 1488437..1489093 - 657 WP_000011658.1 carbon-nitrogen hydrolase family protein -
FGH86_RS07110 1489195..1489425 - 231 WP_000916763.1 DNA polymerase III subunit theta -
FGH86_RS07115 1489564..1489938 + 375 WP_000168747.1 CopC domain-containing protein YobA -
FGH86_RS07120 1489942..1490814 + 873 WP_000879289.1 copper homeostasis membrane protein CopD -
FGH86_RS07125 1490827..1491168 + 342 WP_000976476.1 YebY family protein -
- 1491196..1491467 - 272 - - Antitoxin
- 1491326..1491429 + 104 - - Toxin
FGH86_RS07130 1491564..1492220 + 657 WP_000812724.1 protein-serine/threonine phosphatase -
FGH86_RS07135 1492221..1492412 - 192 WP_000457842.1 YebW family protein -
FGH86_RS07140 1492517..1492753 - 237 WP_001295499.1 DUF1480 family protein -
FGH86_RS07145 1492871..1494310 - 1440 WP_001352260.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 104 bp

>T126446 NZ_CP040667:1491326-1491429 [Escherichia coli]
GGCAAGGCAACTAAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATAC
AGGAATCGTGTTCGGTCTCTTTTT

Antitoxin


Download         Length: 272 bp

>AT126446 NZ_CP040667:c1491467-1491196 [Escherichia coli]
AAAGTCAGCGAAGGAAATGCTTCTGGCTTTTAACAGATAAAAAGAGACCGAACACGATTCCTGTATTCGGTCCAGGGAAA
TGGCTCTTGGGAGAGAGCCGTGCGCTAAAAGTTGGCATTAATGCAGGCTTAGTTGCCTTGCCCTTTAAGAATAGATGACG
ACGCCAGGTTTTCCAGTTTGCGTGCAAAATGGTCAATAAAAAGCGTGGTGGTCATCAGCTGAAATGTTAAAAACCGCCCG
TTCTGGTGAAAGAACTGAGGCGGTTTTTTTAT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References