Detailed information of TA system
Overview
TA module
| Type | VIII | Classification (family/domain) | SdsR-RyeA/- |
| Location | 1993720..1993865 | Replicon | chromosome |
| Accession | NZ_CP040657 | ||
| Organism | Klebsiella pneumoniae strain 2019010306 | ||
Toxin (RNA)
| Gene name | SdsR | ||
| Locus tag | - | ||
| Coordinates | 1993756..1993858 (+) |
Antitoxin (RNA)
| Gene name | RyeA | ||
| Locus tag | - | ||
| Coordinates | 1993720..1993865 (-) |
Genomic Context
| Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
|---|---|---|---|---|---|---|
| E3148_RS09555 | 1988850..1990910 | + | 2061 | WP_004151449.1 | oligopeptidase B | - |
| E3148_RS09560 | 1990914..1991573 | - | 660 | WP_020324964.1 | exodeoxyribonuclease X | - |
| E3148_RS09565 | 1991652..1991882 | - | 231 | WP_002911406.1 | DNA polymerase III subunit theta | - |
| E3148_RS09570 | 1991995..1992369 | + | 375 | WP_004151448.1 | CopC domain-containing protein YobA | - |
| E3148_RS09575 | 1992373..1993242 | + | 870 | WP_004151447.1 | copper homeostasis membrane protein CopD | - |
| E3148_RS09580 | 1993259..1993597 | + | 339 | WP_002911404.1 | YebY family protein | - |
| - | 1993720..1993865 | - | 146 | - | - | Antitoxin |
| - | 1993756..1993858 | + | 103 | - | - | Toxin |
| E3148_RS09585 | 1994234..1994377 | - | 144 | WP_002911398.1 | Ecr family regulatory small membrane protein | - |
| E3148_RS09590 | 1994482..1995450 | - | 969 | WP_004151446.1 | VirK/YbjX family protein | - |
| E3148_RS09595 | 1995607..1996260 | + | 654 | WP_004180432.1 | protein-serine/threonine phosphatase | - |
| E3148_RS09600 | 1996257..1996448 | - | 192 | WP_002911395.1 | YebW family protein | - |
| E3148_RS09605 | 1996546..1996785 | - | 240 | WP_002911393.1 | YebV family protein | - |
| E3148_RS09610 | 1996901..1998334 | - | 1434 | WP_004148845.1 | 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF | - |
Associated MGEs
| MGE detail |
Similar MGEs |
Relative position |
MGE Type | Cargo ARG | Virulence gene | Coordinates | Length (bp) |
|---|
Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.
Sequences
Toxin
Download Length: 103 bp
>T126299 NZ_CP040657:1993756-1993858 [Klebsiella pneumoniae]
GCAAGGCGACTTAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATACA
GGAATCGTATTCGGTCTCTTTTT
GCAAGGCGACTTAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATACA
GGAATCGTATTCGGTCTCTTTTT
Antitoxin
Download Length: 146 bp
>AT126299 NZ_CP040657:c1993865-1993720 [Klebsiella pneumoniae]
TAAAGATAAAAAGAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAG
TTGGCATTAATGCAGGCTAAGTCGCCTTGCACTATAAGAATAGTTTAACGCGTCAGCTTTTCCAGT
TAAAGATAAAAAGAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAG
TTGGCATTAATGCAGGCTAAGTCGCCTTGCACTATAAGAATAGTTTAACGCGTCAGCTTTTCCAGT
