Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) ParST/RES-Xre
Location 2603136..2604006 Replicon chromosome
Accession NZ_CP040656
Organism Lysobacter enzymogenes strain YC36

Toxin (Protein)


Gene name ParT Uniprot ID -
Locus tag FE772_RS11145 Protein ID WP_057947367.1
Coordinates 2603136..2603615 (-) Length 160 a.a.

Antitoxin (Protein)


Gene name ParS Uniprot ID -
Locus tag FE772_RS11150 Protein ID WP_078998564.1
Coordinates 2603650..2604006 (-) Length 119 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
FE772_RS11120 2598377..2599041 - 665 Protein_2212 transcriptional repressor LexA -
FE772_RS11125 2599365..2600105 + 741 WP_082644437.1 GbsR/MarR family transcriptional regulator -
FE772_RS11130 2600167..2601264 + 1098 WP_138884925.1 DUF393 domain-containing protein -
FE772_RS11135 2601308..2602150 + 843 WP_175429362.1 TIGR01777 family oxidoreductase -
FE772_RS11140 2602147..2602869 + 723 WP_138884927.1 DUF4166 domain-containing protein -
FE772_RS11145 2603136..2603615 - 480 WP_057947367.1 RES family NAD+ phosphorylase Toxin
FE772_RS11150 2603650..2604006 - 357 WP_078998564.1 MbcA/ParS/Xre antitoxin family protein Antitoxin
FE772_RS11155 2604607..2605068 + 462 WP_057947369.1 hypothetical protein -
FE772_RS11160 2605603..2606637 + 1035 WP_057947370.1 hypothetical protein -
FE772_RS11165 2606934..2607125 + 192 WP_175429176.1 hypothetical protein -
FE772_RS11170 2607217..2607504 - 288 WP_057947372.1 hypothetical protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

RES domain

(3-144)

Antitoxin

Antitoxin Xre/MbcA/ParS-like, toxin-binding domain

(61-115)


Sequences

Toxin        


Download         Length: 160 a.a.        Molecular weight: 17164.66 Da        Isoelectric Point: 9.9850

>T126295 WP_057947367.1 NZ_CP040656:c2603615-2603136 [Lysobacter enzymogenes]
MTKLWRIAGETRAYRADDLSGAGAAKFPGRWNDEGQRVLYSATSLALAALETAAYVDAHGLPLNRHVVSIEVPPAVWKAR
IQMTAADLPGGWDAVPAGMASVGIGSRWLQSGASAILLVPSVIVPEEYNALINPEHRDAKKLRATTGRKFQYNVVFRAP

Download         Length: 480 bp

>T126295 NZ_CP040656:c2603615-2603136 [Lysobacter enzymogenes]
ATGACGAAACTATGGCGCATCGCCGGCGAGACCCGCGCCTACCGCGCCGACGACCTCAGCGGCGCGGGCGCGGCCAAGTT
TCCCGGGCGTTGGAACGACGAAGGCCAGCGCGTGCTTTACAGCGCGACCTCGCTGGCGCTGGCGGCGCTGGAGACGGCCG
CCTACGTCGACGCCCACGGGCTGCCGTTGAACCGGCACGTGGTGTCGATCGAGGTGCCGCCGGCGGTGTGGAAGGCGCGC
ATCCAGATGACCGCCGCCGACCTGCCCGGCGGCTGGGACGCGGTGCCGGCGGGCATGGCCAGCGTCGGCATCGGCTCGCG
CTGGCTGCAGTCCGGCGCCTCGGCGATCCTGCTGGTGCCGTCGGTGATCGTGCCGGAGGAGTACAACGCGCTGATCAATC
CCGAGCATCGCGACGCCAAGAAGCTGCGCGCCACGACCGGGCGCAAGTTCCAGTACAACGTGGTGTTCCGCGCGCCTTGA

Antitoxin


Download         Length: 119 a.a.        Molecular weight: 12256.02 Da        Isoelectric Point: 4.9905

>AT126295 WP_078998564.1 NZ_CP040656:c2604006-2603650 [Lysobacter enzymogenes]
MVKHMASDMDLPAVRMFDILGIAKATAEAKAAQQARITGASGQAALGLIHLLGIARDIVDDSTDPAAPDFDAARWLGHWI
EQPQAALGGQRPADLLDTPTGLSVVARLLGALASGAYQ

Download         Length: 357 bp

>AT126295 NZ_CP040656:c2604006-2603650 [Lysobacter enzymogenes]
ATGGTCAAGCACATGGCCAGCGACATGGACCTGCCGGCGGTGCGCATGTTCGACATCCTCGGCATCGCCAAGGCCACCGC
CGAGGCCAAGGCCGCGCAGCAGGCGCGCATCACCGGCGCCAGCGGCCAGGCCGCGCTGGGGCTGATCCACCTGCTCGGCA
TCGCCCGCGACATCGTCGACGACAGCACCGATCCGGCCGCGCCCGACTTCGACGCGGCGCGCTGGCTCGGCCACTGGATC
GAGCAGCCGCAGGCGGCGCTGGGTGGACAGCGGCCGGCCGACCTGCTCGACACCCCGACCGGGCTCAGCGTGGTCGCGCG
CCTGCTCGGCGCGCTGGCCAGCGGCGCGTACCAGTGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References