Detailed information of TA system TA126295

Bioinformatically predicted

Overview

TA module

• Type: II
• Classification (family/domain): ParST/RES-Xre
• Location: 2603136..2604006
• Replicon: chromosome
• Accession: NZ_CP040656
• Organism: Lysobacter enzymogenes strain YC36

Toxin (Protein)

• Gene name: ParT
• Uniprot ID: -
• Locus tag: FE772_RS11145
• Protein ID: WP_057947367.1
• Coordinates: 2603136..2603615 (-)
• Length: 160 a.a.

Antitoxin (Protein)

• Gene name: ParS
• Uniprot ID: -
• Locus tag: FE772_RS11150
• Protein ID: WP_078998564.1
• Coordinates: 2603650..2604006 (-)
• Length: 119 a.a.

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
FE772_RS11120	2598377..2599041	-	665	Protein_2212	transcriptional repressor LexA	-
FE772_RS11125	2599365..2600105	+	741	WP_082644437.1	GbsR/MarR family transcriptional regulator	-
FE772_RS11130	2600167..2601264	+	1098	WP_138884925.1	DUF393 domain-containing protein	-
FE772_RS11135	2601308..2602150	+	843	WP_175429362.1	TIGR01777 family oxidoreductase	-
FE772_RS11140	2602147..2602869	+	723	WP_138884927.1	DUF4166 domain-containing protein	-
FE772_RS11145	2603136..2603615	-	480	WP_057947367.1	RES family NAD+ phosphorylase	Toxin
FE772_RS11150	2603650..2604006	-	357	WP_078998564.1	MbcA/ParS/Xre antitoxin family protein	Antitoxin
FE772_RS11155	2604607..2605068	+	462	WP_057947369.1	hypothetical protein	-
FE772_RS11160	2605603..2606637	+	1035	WP_057947370.1	hypothetical protein	-
FE772_RS11165	2606934..2607125	+	192	WP_175429176.1	hypothetical protein	-
FE772_RS11170	2607217..2607504	-	288	WP_057947372.1	hypothetical protein	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

• RES domain (3-144)

Antitoxin

• Antitoxin Xre/MbcA/ParS-like, toxin-binding domain (61-115)

Sequences

Toxin

Protein

• Length: 160 a.a.
• Molecular weight: 17164.66 Da
• Isoelectric Point: 9.9850

>T126295 WP_057947367.1 NZ_CP040656:c2603615-2603136 [Lysobacter enzymogenes]
MTKLWRIAGETRAYRADDLSGAGAAKFPGRWNDEGQRVLYSATSLALAALETAAYVDAHGLPLNRHVVSIEVPPAVWKAR
IQMTAADLPGGWDAVPAGMASVGIGSRWLQSGASAILLVPSVIVPEEYNALINPEHRDAKKLRATTGRKFQYNVVFRAP

Nucleotide

• Length: 480 bp

>T126295 NZ_CP040656:c2603615-2603136 [Lysobacter enzymogenes]
ATGACGAAACTATGGCGCATCGCCGGCGAGACCCGCGCCTACCGCGCCGACGACCTCAGCGGCGCGGGCGCGGCCAAGTT
TCCCGGGCGTTGGAACGACGAAGGCCAGCGCGTGCTTTACAGCGCGACCTCGCTGGCGCTGGCGGCGCTGGAGACGGCCG
CCTACGTCGACGCCCACGGGCTGCCGTTGAACCGGCACGTGGTGTCGATCGAGGTGCCGCCGGCGGTGTGGAAGGCGCGC
ATCCAGATGACCGCCGCCGACCTGCCCGGCGGCTGGGACGCGGTGCCGGCGGGCATGGCCAGCGTCGGCATCGGCTCGCG
CTGGCTGCAGTCCGGCGCCTCGGCGATCCTGCTGGTGCCGTCGGTGATCGTGCCGGAGGAGTACAACGCGCTGATCAATC
CCGAGCATCGCGACGCCAAGAAGCTGCGCGCCACGACCGGGCGCAAGTTCCAGTACAACGTGGTGTTCCGCGCGCCTTGA

Antitoxin

Protein

• Length: 119 a.a.
• Molecular weight: 12256.02 Da
• Isoelectric Point: 4.9905

>AT126295 WP_078998564.1 NZ_CP040656:c2604006-2603650 [Lysobacter enzymogenes]
MVKHMASDMDLPAVRMFDILGIAKATAEAKAAQQARITGASGQAALGLIHLLGIARDIVDDSTDPAAPDFDAARWLGHWI
EQPQAALGGQRPADLLDTPTGLSVVARLLGALASGAYQ

Nucleotide

• Length: 357 bp

>AT126295 NZ_CP040656:c2604006-2603650 [Lysobacter enzymogenes]
ATGGTCAAGCACATGGCCAGCGACATGGACCTGCCGGCGGTGCGCATGTTCGACATCCTCGGCATCGCCAAGGCCACCGC
CGAGGCCAAGGCCGCGCAGCAGGCGCGCATCACCGGCGCCAGCGGCCAGGCCGCGCTGGGGCTGATCCACCTGCTCGGCA
TCGCCCGCGACATCGTCGACGACAGCACCGATCCGGCCGCGCCCGACTTCGACGCGGCGCGCTGGCTCGGCCACTGGATC
GAGCAGCCGCAGGCGGCGCTGGGTGGACAGCGGCCGGCCGACCTGCTCGACACCCCGACCGGGCTCAGCGTGGTCGCGCG
CCTGCTCGGCGCGCTGGCCAGCGGCGCGTACCAGTGA