Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relBE/RelE-RelB
Location 305345..305943 Replicon plasmid unnamed2
Accession NZ_CP040642
Organism Agrobacterium sp. T29

Toxin (Protein)


Gene name relE Uniprot ID -
Locus tag FGF54_RS26510 Protein ID WP_142781872.1
Coordinates 305345..305638 (-) Length 98 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID -
Locus tag FGF54_RS26515 Protein ID WP_142781873.1
Coordinates 305635..305943 (-) Length 103 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
FGF54_RS26495 301774..303213 - 1440 WP_142781995.1 PAS domain-containing protein -
FGF54_RS26500 303583..303861 + 279 WP_142781870.1 HU family DNA-binding protein -
FGF54_RS27405 303901..304071 - 171 WP_168208279.1 hypothetical protein -
FGF54_RS26505 304389..304688 - 300 WP_142781871.1 DUF736 domain-containing protein -
FGF54_RS26510 305345..305638 - 294 WP_142781872.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
FGF54_RS26515 305635..305943 - 309 WP_142781873.1 type II toxin-antitoxin system RelB/DinJ family antitoxin Antitoxin
FGF54_RS26530 306534..307142 - 609 WP_142781875.1 DNA-3-methyladenine glycosylase I -
FGF54_RS26535 307146..307433 - 288 WP_142781876.1 hypothetical protein -
FGF54_RS26540 307485..308108 - 624 WP_142781877.1 TetR/AcrR family transcriptional regulator -
FGF54_RS26545 308140..309231 - 1092 WP_142781878.1 alkene reductase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Conjugative plasmid - - 1..451191 451191


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(4-90)

Antitoxin

RelB antitoxin/Antitoxin DinJ

(4-52)


Sequences

Toxin        


Download         Length: 98 a.a.        Molecular weight: 10505.80 Da        Isoelectric Point: 5.6558

>T126242 WP_142781872.1 NZ_CP040642:c305638-305345 [Agrobacterium sp. T29]
VKLVWSAFALSDRDGIFTHIEADNPAAAISVDERITSAARRLTDFPESGRPGRVDGTRELVITGTPYIAAYTVSETTVRV
LRVLHGAQQWPDTLPGG

Download         Length: 294 bp

>T126242 NZ_CP040642:c305638-305345 [Agrobacterium sp. T29]
GTGAAACTGGTATGGTCGGCTTTTGCGCTTTCCGATCGCGACGGCATATTCACTCATATAGAGGCGGATAATCCCGCTGC
TGCTATCTCTGTCGATGAACGGATCACAAGCGCCGCTCGCCGCCTTACCGATTTCCCCGAGAGCGGCCGTCCGGGCAGGG
TTGATGGCACACGCGAATTGGTGATCACAGGTACGCCATACATCGCGGCTTACACCGTCTCGGAAACGACTGTGCGCGTC
CTTCGCGTTTTGCACGGCGCGCAACAGTGGCCGGACACATTGCCCGGCGGCTGA

Antitoxin


Download         Length: 103 a.a.        Molecular weight: 11058.50 Da        Isoelectric Point: 5.1457

>AT126242 WP_142781873.1 NZ_CP040642:c305943-305635 [Agrobacterium sp. T29]
MAANALVQTRIDADVRDRASAVLESMGLTVSDAVRILLTRTANEGALPLELVSGGEAHDTWFRAKVLEALNDVRPDIPAD
EVEAHFARRRMAAARRSGDMTS

Download         Length: 309 bp

>AT126242 NZ_CP040642:c305943-305635 [Agrobacterium sp. T29]
ATGGCCGCAAATGCTCTCGTTCAAACCCGCATCGACGCCGATGTCCGGGACCGCGCATCGGCTGTGCTGGAAAGCATGGG
CCTTACAGTTTCTGACGCAGTTCGCATCCTGCTGACCCGTACCGCCAACGAAGGCGCCCTGCCGCTGGAGCTCGTATCGG
GCGGTGAGGCGCATGATACCTGGTTCCGTGCCAAGGTGCTGGAGGCGCTCAACGATGTCAGGCCAGACATTCCCGCCGAT
GAAGTCGAGGCGCATTTCGCACGGCGCCGGATGGCTGCGGCACGCCGTTCGGGCGATATGACATCGTGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References