Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) hipBA/HipA-couple_hipB
Location 946142..947665 Replicon chromosome
Accession NZ_CP040641
Organism Agrobacterium sp. T29

Toxin (Protein)


Gene name HipA1 Uniprot ID -
Locus tag FGF54_RS19405 Protein ID WP_142780809.1
Coordinates 946421..947665 (+) Length 415 a.a.

Antitoxin (Protein)


Gene name HipB1 Uniprot ID -
Locus tag FGF54_RS19400 Protein ID WP_142780808.1
Coordinates 946142..946408 (+) Length 89 a.a.

Genomic Context

FGF54_RS19380FGF54_RS19385FGF54_RS19390FGF54_RS19400FGF54_RS19405FGF54_RS19410FGF54_RS19415FGF54_RS19420FGF54_RS19395
Location: 941901..942842 (942 bp)
Type: Others
Protein ID: WP_142780804.1
Location: 942898..943827 (930 bp)
Type: Others
Protein ID: WP_142780805.1
Location: 944006..945109 (1104 bp)
Type: Others
Protein ID: WP_142780806.1
Location: 946142..946408 (267 bp)
Type: Antitoxin
Protein ID: WP_142780808.1
Location: 946421..947665 (1245 bp)
Type: Toxin
Protein ID: WP_142780809.1
Location: 947912..948994 (1083 bp)
Type: Others
Protein ID: WP_142780810.1
Location: 949524..950420 (897 bp)
Type: Others
Protein ID: WP_142780811.1
Location: 950497..950886 (390 bp)
Type: Others
Protein ID: WP_142780812.1
Location: 945392..945769 (378 bp)
Type: Others
Protein ID: WP_142780807.1
ToxinAntitoxinOther genes
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Locus tag
Coordinates
Strand
Size (bp)
Protein ID
Product
Description
FGF54_RS19380941901..942842+942WP_142780804.1sugar phosphate isomerase/epimerase-
FGF54_RS19385942898..943827+930WP_142780805.1sugar phosphate isomerase/epimerase-
FGF54_RS19390944006..945109+1104WP_142780806.1agmatine deiminase family protein-
FGF54_RS19395945392..945769-378WP_142780807.1HNH endonuclease-
FGF54_RS19400946142..946408+267WP_142780808.1helix-turn-helix transcriptional regulatorAntitoxin
FGF54_RS19405946421..947665+1245WP_142780809.1type II toxin-antitoxin system HipA family toxinToxin
FGF54_RS19410947912..948994+1083WP_142780810.1hypothetical protein-
FGF54_RS19415949524..950420+897WP_142780811.1hypothetical protein-
FGF54_RS19420950497..950886+390WP_142780812.1hypothetical protein-

Associated MGEs

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MGE
detail
Similar
MGEs
Relative
position
MGE Type
Cargo ARG
Virulence gene
Coordinates
Length (bp)
-insideGenomic island--946142..96542319281


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

HipA-like, C-terminal

(137-370)

Antitoxin

Cro/C1-type helix-turn-helix domain

(9-66)


Sequences

Toxin        


Download         Length: 415 a.a.        Molecular weight: 45860.49 Da        Isoelectric Point: 6.8295

>T126241 WP_142780809.1 NZ_CP040641:946421-947665 [Agrobacterium sp. T29]
MTTIYYENWSVAHLSDQDGLALSYDAEWEKRSSAFPLSLTTPMRAGSYGAERVMPWLANLLPETHLSEIGQQLKVSPQDV
IGLLLRVGRDTAGAFSIGEPRREGNNFRIVDDGEALERIIDELPERPFLIGERGVSMSLAGVQDKLPVYIDYEGRIGIPV
DGTPSTHILKPDIKRLAGSVTNEAFCMILARLCGLDVAEVTMGRAGTRDYLLVRRYDRVADRQGVIRRIHQEDFCQLLGL
FPAEKYEQTGLGQRGGASLPQMFQALARLVSPAERIRLLDAVIFNILICNSDSHAKNYSVLVGASGTARLAPLYDLMCAS
PYKQVDQSLPQQLAGKRNADELHAKDWRQFAADVGLSPAAVTRRVVELAALVATKADEALDHVQSYPVSNRELASSLVFL
IRKRCRRIERQISA

Download         Length: 1245 bp

>T126241 NZ_CP040641:946421-947665 [Agrobacterium sp. T29]
TTGACGACTATCTACTACGAGAACTGGTCTGTTGCGCACTTGTCGGATCAGGATGGCCTAGCTCTCTCATACGACGCAGA
GTGGGAGAAACGGTCCTCAGCCTTCCCATTGTCGCTTACGACGCCAATGCGCGCAGGCAGCTATGGGGCCGAACGGGTCA
TGCCGTGGCTCGCGAACCTGCTGCCGGAAACCCATCTGTCCGAAATTGGCCAGCAGCTCAAGGTGTCGCCCCAGGACGTA
ATCGGTCTCCTGCTGCGTGTCGGCCGCGATACGGCAGGTGCCTTCTCGATCGGTGAGCCGCGACGGGAGGGAAATAATTT
CCGCATCGTCGATGACGGGGAAGCACTTGAGCGCATCATCGACGAACTGCCGGAGCGGCCATTCCTGATCGGTGAGCGGG
GCGTCTCAATGTCGCTTGCAGGCGTCCAGGACAAGCTCCCCGTCTACATCGATTACGAAGGTCGGATCGGCATACCGGTT
GACGGCACCCCTTCGACCCACATCCTGAAGCCCGACATCAAACGTCTTGCGGGGAGCGTCACCAATGAAGCGTTCTGCAT
GATCCTCGCAAGGCTCTGCGGGCTGGACGTTGCCGAAGTGACAATGGGCCGTGCAGGAACACGGGACTATCTTCTCGTCC
GCCGCTATGACCGGGTTGCTGACCGCCAAGGTGTCATCCGCCGCATACACCAAGAAGACTTCTGCCAGCTGCTGGGACTG
TTCCCGGCGGAGAAGTATGAGCAAACCGGTCTCGGTCAGCGTGGCGGCGCATCACTGCCGCAGATGTTTCAAGCCTTGGC
GCGCCTTGTCTCGCCCGCCGAACGCATCCGTCTGCTTGACGCGGTGATCTTCAACATCCTGATCTGTAACTCGGACTCGC
ATGCGAAAAACTACTCGGTGCTTGTCGGCGCGTCCGGCACCGCGAGACTCGCGCCGCTCTACGATCTGATGTGCGCGTCA
CCCTACAAGCAGGTCGATCAATCTCTGCCCCAGCAACTGGCCGGCAAGCGCAACGCCGACGAGTTGCACGCGAAGGACTG
GCGTCAGTTTGCCGCCGATGTCGGGCTTAGTCCCGCTGCCGTAACCAGGCGCGTCGTGGAGCTCGCCGCTCTGGTCGCGA
CCAAGGCAGACGAGGCACTTGACCACGTCCAATCGTACCCGGTTTCAAATCGCGAACTTGCGTCCAGCCTCGTCTTTCTC
ATCAGGAAGAGATGTAGGCGGATCGAGCGGCAGATTTCGGCCTGA

Antitoxin


Download         Length: 89 a.a.        Molecular weight: 9698.03 Da        Isoelectric Point: 5.0648

>AT126241 WP_142780808.1 NZ_CP040641:946142-946408 [Agrobacterium sp. T29]
MIRSAAEFGALVREYRKKQGWTQTQLAERCGTGERFIVDLENGKPSCQLEKSLIAARTVGLNLGDLNAISSLPIPAADDD
LDYLPRFS

Download         Length: 267 bp

>AT126241 NZ_CP040641:946142-946408 [Agrobacterium sp. T29]
ATGATCCGTTCAGCGGCAGAATTCGGCGCGCTTGTTCGAGAATACCGAAAGAAGCAGGGATGGACGCAAACCCAGCTCGC
TGAGCGCTGTGGCACCGGGGAACGCTTCATCGTCGATCTAGAAAACGGCAAGCCAAGCTGTCAGCTTGAGAAATCCCTGA
TCGCGGCCAGAACGGTTGGACTTAACCTCGGCGACCTGAATGCGATCTCGTCCTTGCCGATTCCGGCAGCCGATGACGAC
CTCGACTACCTGCCGCGCTTTTCCTGA

Similar Proteins

Only experimentally validated proteins are listed.

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Protein
Organism
Identities (%)
Coverage (%)
Ha-value
No matching records found
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Protein
Organism
Identities (%)
Coverage (%)
Ha-value
No matching records found

Structures

Toxin

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Source
ID
Structure
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Antitoxin

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Source
ID
Structure
No matching records found

References