Detailed information of TA system TA126240

Bioinformatically predicted

Overview

TA module

• Type: II
• Classification (family/domain): BrnTA/BrnT-BrnA
• Location: 595338..595906
• Replicon: chromosome
• Accession: NZ_CP040641
• Organism: Agrobacterium sp. T29

Toxin (Protein)

• Gene name: brnT
• Uniprot ID: -
• Locus tag: FGF54_RS17685
• Protein ID: WP_142780596.1
• Coordinates: 595338..595592 (+)
• Length: 85 a.a.

Antitoxin (Protein)

• Gene name: brnA
• Uniprot ID: -
• Locus tag: FGF54_RS17690
• Protein ID: WP_142780597.1
• Coordinates: 595583..595906 (+)
• Length: 108 a.a.

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
FGF54_RS17660	591717..592232	+	516	WP_142780592.1	disulfide bond formation protein B	-
FGF54_RS17665	592263..592820	-	558	WP_003585610.1	HNH endonuclease	-
FGF54_RS17670	593169..593468	+	300	WP_142780593.1	hypothetical protein	-
FGF54_RS17675	593615..594220	+	606	WP_142780594.1	transglutaminase-like cysteine peptidase	-
FGF54_RS17680	594483..595274	+	792	WP_142780595.1	serine/threonine protein phosphatase	-
FGF54_RS17685	595338..595592	+	255	WP_142780596.1	BrnT family toxin	Toxin
FGF54_RS17690	595583..595906	+	324	WP_142780597.1	BrnA antitoxin family protein	Antitoxin
FGF54_RS17695	595989..597215	-	1227	WP_142780598.1	glycosyltransferase family 4 protein	-
FGF54_RS17700	597224..598549	-	1326	WP_142781564.1	polysaccharide pyruvyl transferase family protein	-
FGF54_RS17705	598537..600021	-	1485	WP_142780599.1	lipopolysaccharide biosynthesis protein	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

• Ribonuclease toxin, BrnT, of type II toxin-antitoxin system (5-78)

Antitoxin

• BrnA antitoxin of type II toxin-antitoxin system (28-102)

Sequences

Toxin

Protein

• Length: 85 a.a.
• Molecular weight: 9368.98 Da
• Isoelectric Point: 8.0166

>T126240 WP_142780596.1 NZ_CP040641:595338-595592 [Agrobacterium sp. T29]
MKITYDETKRLTNIEKHGLDFADLTIEFFVGSIVLPAKEDRFMAIGELQGRIIIAVVFSPLGSQALSVISMRPASTKERR
LSCP

Nucleotide

• Length: 255 bp

>T126240 NZ_CP040641:595338-595592 [Agrobacterium sp. T29]
ATGAAAATCACTTATGACGAAACGAAGCGGCTAACGAATATCGAGAAGCATGGCCTCGATTTTGCCGATCTGACGATAGA
GTTCTTTGTAGGCTCTATCGTTCTTCCCGCCAAGGAAGACCGCTTTATGGCGATAGGTGAGCTTCAGGGTCGCATCATCA
TTGCGGTGGTGTTCAGCCCGCTAGGTTCGCAGGCCCTGTCCGTCATTTCCATGCGGCCAGCCAGCACCAAGGAAAGGAGG
CTCTCATGCCCTTAA

Antitoxin

Protein

• Length: 108 a.a.
• Molecular weight: 11940.74 Da
• Isoelectric Point: 10.2394

>AT126240 WP_142780597.1 NZ_CP040641:595583-595906 [Agrobacterium sp. T29]
MPLKFSSKRPLTNKEEAEIQKMIASDPDAPEATDKEMAQAKPFGAVFPDLAKSIDREIARRGRPRADAPKTPVTIRLDPD
LVEHYKAMGKGWQSRINSDLRKLSGLP

Nucleotide

• Length: 324 bp

>AT126240 NZ_CP040641:595583-595906 [Agrobacterium sp. T29]
ATGCCCTTAAAATTTTCTTCGAAACGCCCGCTTACCAATAAGGAAGAAGCGGAGATTCAGAAAATGATAGCGTCCGATCC
GGACGCCCCCGAAGCCACCGATAAAGAGATGGCGCAAGCCAAACCGTTCGGGGCGGTTTTCCCTGACCTTGCCAAGAGCA
TTGATCGGGAAATTGCGCGCCGTGGCAGGCCAAGGGCGGATGCACCGAAAACGCCGGTTACGATCCGTCTCGATCCTGAT
TTAGTGGAGCACTACAAAGCCATGGGCAAAGGCTGGCAGTCACGCATCAATAGCGACCTGAGAAAGCTATCAGGTCTTCC
CTGA