Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) vapBC/VapC-VagC
Location 794481..795112 Replicon chromosome
Accession NZ_CP040640
Organism Agrobacterium sp. T29

Toxin (Protein)


Gene name vapC Uniprot ID -
Locus tag FGF54_RS04110 Protein ID WP_142778994.1
Coordinates 794714..795112 (+) Length 133 a.a.

Antitoxin (Protein)


Gene name vapB Uniprot ID A0A420GCG3
Locus tag FGF54_RS04105 Protein ID WP_031233980.1
Coordinates 794481..794714 (+) Length 78 a.a.

Genomic Context

FGF54_RS04080FGF54_RS04090FGF54_RS04095FGF54_RS04100FGF54_RS04105FGF54_RS04110FGF54_RS04115FGF54_RS04120FGF54_RS04125FGF54_RS04130
Location: 789951..791213 (1263 bp)
Type: Others
Protein ID: WP_142778992.1
Location: 791543..792763 (1221 bp)
Type: Others
Protein ID: WP_142778993.1
Location: 792832..793719 (888 bp)
Type: Others
Protein ID: WP_003520732.1
Location: 793725..794387 (663 bp)
Type: Others
Protein ID: WP_003502089.1
Location: 794481..794714 (234 bp)
Type: Antitoxin
Protein ID: WP_031233980.1
Location: 794714..795112 (399 bp)
Type: Toxin
Protein ID: WP_142778994.1
Location: 795145..795795 (651 bp)
Type: Others
Protein ID: WP_142778995.1
Location: 795869..796699 (831 bp)
Type: Others
Protein ID: WP_142778996.1
Location: 796699..797721 (1023 bp)
Type: Others
Protein ID: WP_142778997.1
Location: 797748..798695 (948 bp)
Type: Others
Protein ID: WP_003520739.1
ToxinAntitoxinOther genes
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Locus tag
Coordinates
Strand
Size (bp)
Protein ID
Product
Description
FGF54_RS04080789951..791213+1263WP_142778992.1beta-ketoacyl-ACP synthase II-
FGF54_RS04090791543..792763+1221WP_142778993.1endolytic transglycosylase MltG-
FGF54_RS04095792832..793719+888WP_003520732.1YicC family protein-
FGF54_RS04100793725..794387+663WP_003502089.1guanylate kinase-
FGF54_RS04105794481..794714+234WP_031233980.1antitoxinAntitoxin
FGF54_RS04110794714..795112+399WP_142778994.1type II toxin-antitoxin system VapC family toxinToxin
FGF54_RS04115795145..795795-651WP_142778995.1alpha/beta hydrolase-
FGF54_RS04120795869..796699-831WP_142778996.116S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))- dimethyltransferase RsmA-
FGF54_RS04125796699..797721-1023WP_142778997.14-hydroxythreonine-4-phosphate dehydrogenase PdxA-
FGF54_RS04130797748..798695-948WP_003520739.1peptidylprolyl isomerase-

Associated MGEs

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MGE
detail
Similar
MGEs
Relative
position
MGE Type
Cargo ARG
Virulence gene
Coordinates
Length (bp)
No matching records found


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

PIN domain

(4-124)

Antitoxin

SpoVT-AbrB domain

(7-49)


Sequences

Toxin        


Download         Length: 133 a.a.        Molecular weight: 14866.16 Da        Isoelectric Point: 6.7038

>T126237 WP_142778994.1 NZ_CP040640:794714-795112 [Agrobacterium sp. T29]
MLTYMLDTNICIYVMKTYPPELREKFNALADQLCISSITLGELYYGAEKSIRRQENINAIENFTARLDVLPFADKGAAHY
GQIRAELAKAGTPCGVHDMQIGGHARSEGLIVVTNNMREFVRMPGLRVENWV

Download         Length: 399 bp

>T126237 NZ_CP040640:794714-795112 [Agrobacterium sp. T29]
ATGCTTACATATATGCTCGATACCAACATATGTATCTATGTGATGAAGACTTATCCTCCGGAGCTGCGGGAGAAATTCAA
CGCTCTGGCAGATCAACTGTGTATTTCGAGCATCACACTTGGCGAGCTTTATTATGGTGCTGAAAAATCCATCCGGCGCC
AGGAAAACATCAACGCCATTGAAAATTTTACTGCGCGTTTGGACGTTCTGCCTTTCGCCGACAAAGGCGCCGCACATTAC
GGACAGATCAGGGCCGAACTTGCCAAGGCTGGAACGCCATGCGGCGTTCATGATATGCAGATTGGTGGTCACGCCCGTAG
CGAGGGGCTGATCGTCGTAACCAATAATATGCGCGAGTTTGTCCGGATGCCCGGTTTGCGAGTTGAAAACTGGGTTTAG

Antitoxin


Download         Length: 78 a.a.        Molecular weight: 8649.92 Da        Isoelectric Point: 5.7974

>AT126237 WP_031233980.1 NZ_CP040640:794481-794714 [Agrobacterium sp. T29]
MATSTVFISNRSQAVRLPKAVAFPDDVHKVDVLKIGLARVIVPQGKRWDDLFLTGPRATDDFLSVREEPALDEREPF

Download         Length: 234 bp

>AT126237 NZ_CP040640:794481-794714 [Agrobacterium sp. T29]
ATGGCTACGTCAACGGTTTTTATAAGCAATCGCAGTCAAGCTGTAAGGCTACCGAAGGCCGTGGCTTTTCCTGATGACGT
GCATAAGGTCGATGTTCTGAAAATCGGTCTCGCGCGTGTTATAGTGCCGCAGGGAAAGCGCTGGGACGACCTTTTTCTGA
CCGGCCCACGTGCAACGGATGATTTTCTTTCCGTTCGCGAAGAGCCTGCATTGGATGAGCGCGAGCCCTTCTGA

Similar Proteins

Only experimentally validated proteins are listed.

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Protein
Organism
Identities (%)
Coverage (%)
Ha-value
No matching records found
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Protein
Organism
Identities (%)
Coverage (%)
Ha-value
No matching records found

Structures

Toxin

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Source
ID
Structure
No matching records found

Antitoxin

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Source
ID
Structure
AlphaFold DBA0A420GCG3

References