Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) mazEF/MazF-MazE
Location 623083..623708 Replicon chromosome
Accession NZ_CP040640
Organism Agrobacterium sp. T29

Toxin (Protein)


Gene name mazF Uniprot ID -
Locus tag FGF54_RS03215 Protein ID WP_125144642.1
Coordinates 623349..623708 (+) Length 120 a.a.

Antitoxin (Protein)


Gene name mazE Uniprot ID A0A420FBH4
Locus tag FGF54_RS03210 Protein ID WP_059753836.1
Coordinates 623083..623349 (+) Length 89 a.a.

Genomic Context

FGF54_RS03185FGF54_RS03190FGF54_RS03195FGF54_RS03200FGF54_RS03205FGF54_RS03210FGF54_RS03215FGF54_RS03225FGF54_RS03220FGF54_RS03230FGF54_RS03235
Location: 618109..618933 (825 bp)
Type: Others
Protein ID: WP_020811374.1
Location: 618975..619583 (609 bp)
Type: Others
Protein ID: WP_142778904.1
Location: 619759..622341 (2583 bp)
Type: Others
Protein ID: WP_168207991.1
Location: 622338..622760 (423 bp)
Type: Others
Protein ID: WP_142778905.1
Location: 622814..623014 (201 bp)
Type: Others
Protein ID: WP_080817386.1
Location: 623083..623349 (267 bp)
Type: Antitoxin
Protein ID: WP_059753836.1
Location: 623349..623708 (360 bp)
Type: Toxin
Protein ID: WP_125144642.1
Location: 624157..625566 (1410 bp)
Type: Others
Protein ID: WP_210247430.1
Location: 623729..623977 (249 bp)
Type: Others
Protein ID: WP_142778906.1
Location: 625557..625730 (174 bp)
Type: Others
Protein ID: WP_078051557.1
Location: 625799..627514 (1716 bp)
Type: Others
Protein ID: WP_142778907.1
ToxinAntitoxinOther genes
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Locus tag
Coordinates
Strand
Size (bp)
Protein ID
Product
Description
FGF54_RS03185618109..618933+825WP_020811374.1class D beta-lactamase-
FGF54_RS03190618975..619583+609WP_142778904.1class I SAM-dependent methyltransferase-
FGF54_RS03195619759..622341+2583WP_168207991.1heavy metal translocating P-type ATPase-
FGF54_RS03200622338..622760+423WP_142778905.1Cu(I)-responsive transcriptional regulator-
FGF54_RS03205622814..623014+201WP_080817386.1heavy-metal-associated domain-containing protein-
FGF54_RS03210623083..623349+267WP_059753836.1AbrB/MazE/SpoVT family DNA-binding domain-containing proteinAntitoxin
FGF54_RS03215623349..623708+360WP_125144642.1type II toxin-antitoxin system PemK/MazF family toxinToxin
FGF54_RS03220623729..623977-249WP_142778906.1hypothetical protein-
FGF54_RS03225624157..625566+1410WP_210247430.1MFS transporter-
FGF54_RS03230625557..625730-174WP_078051557.1hypothetical protein-
FGF54_RS03235625799..627514-1716WP_142778907.1glycoside hydrolase family 32 protein-

Associated MGEs

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MGE
detail
Similar
MGEs
Relative
position
MGE Type
Cargo ARG
Virulence gene
Coordinates
Length (bp)
No matching records found


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

mRNA interferase PemK-like

(8-115)

Antitoxin

SpoVT-AbrB domain

(14-52)


Sequences

Toxin        


Download         Length: 120 a.a.        Molecular weight: 12924.08 Da        Isoelectric Point: 8.2824

>T126236 WP_125144642.1 NZ_CP040640:623349-623708 [Agrobacterium sp. T29]
MVRSQVPKRGDVYLVDLNPVIGSEIRDEHRCIVITPREINAVGLCLVVPVTTGGVFTRRAGLAVNISGHRTTGVALCNQV
RSMDIVARVAQKKAKYIETLDDATIDEIAGRVISMIDPV

Download         Length: 360 bp

>T126236 NZ_CP040640:623349-623708 [Agrobacterium sp. T29]
ATGGTCCGCAGCCAGGTTCCAAAACGTGGCGACGTTTATCTGGTCGACCTCAATCCTGTCATCGGCAGCGAAATCAGGGA
CGAGCATCGTTGTATCGTCATCACGCCCAGAGAAATCAACGCGGTTGGACTGTGCCTTGTCGTTCCCGTGACGACGGGTG
GAGTATTCACACGCAGGGCAGGGCTTGCCGTGAACATATCGGGCCACAGGACAACGGGTGTCGCGCTATGCAATCAGGTG
AGAAGCATGGACATTGTTGCCCGTGTCGCCCAGAAAAAAGCGAAATATATCGAAACCCTTGACGATGCGACGATCGACGA
AATCGCCGGTCGTGTCATCAGCATGATCGATCCCGTCTGA

Antitoxin


Download         Length: 89 a.a.        Molecular weight: 9424.90 Da        Isoelectric Point: 4.5983

>AT126236 WP_059753836.1 NZ_CP040640:623083-623349 [Agrobacterium sp. T29]
MTVTTRIRRQGGAAVMTIPPALLKMLGLEIGEQLTLEVDNGALVASPVRQEKKRFTLAELLEGADEVAALNASAREWDEA
PPVGKEAL

Download         Length: 267 bp

>AT126236 NZ_CP040640:623083-623349 [Agrobacterium sp. T29]
ATGACCGTAACGACGAGAATAAGACGTCAGGGCGGTGCGGCGGTGATGACCATCCCGCCCGCTCTTTTGAAGATGCTGGG
GCTGGAAATCGGTGAACAACTGACACTTGAGGTCGACAACGGCGCGCTGGTCGCCAGCCCGGTTCGGCAGGAAAAGAAGC
GCTTCACGCTTGCAGAACTGCTGGAGGGTGCGGATGAAGTCGCCGCCCTCAATGCCAGCGCGCGGGAATGGGACGAAGCG
CCGCCAGTTGGTAAAGAAGCCCTTTGA

Similar Proteins

Only experimentally validated proteins are listed.

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Protein
Organism
Identities (%)
Coverage (%)
Ha-value
No matching records found
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Protein
Organism
Identities (%)
Coverage (%)
Ha-value
No matching records found

Structures

Toxin

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Source
ID
Structure
No matching records found

Antitoxin

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Source
ID
Structure
AlphaFold DBA0A420FBH4

References