Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) PumA-relB/upstrm_HI1419-dnstrm_HI1420
Location 533048..533642 Replicon chromosome
Accession NZ_CP040640
Organism Agrobacterium sp. T29

Toxin (Protein)


Gene name PumA Uniprot ID -
Locus tag FGF54_RS02690 Protein ID WP_137003032.1
Coordinates 533328..533642 (-) Length 105 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID -
Locus tag FGF54_RS02685 Protein ID WP_080833761.1
Coordinates 533048..533347 (-) Length 100 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
FGF54_RS02660 528178..529176 + 999 WP_142778852.1 asparaginase -
FGF54_RS02665 529311..529931 + 621 WP_078051121.1 glutathione S-transferase family protein -
FGF54_RS02670 530083..530742 - 660 WP_142778853.1 glutathione S-transferase family protein -
FGF54_RS02675 530825..531340 - 516 WP_142778854.1 MarR family transcriptional regulator -
FGF54_RS02680 531482..533011 + 1530 WP_168207983.1 MFS transporter -
FGF54_RS02685 533048..533347 - 300 WP_080833761.1 putative addiction module antidote protein Antitoxin
FGF54_RS02690 533328..533642 - 315 WP_137003032.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
FGF54_RS02695 533880..534890 + 1011 WP_142780109.1 ligase-associated DNA damage response exonuclease -
FGF54_RS02700 534892..536517 + 1626 WP_142778855.1 cisplatin damage response ATP-dependent DNA ligase -
FGF54_RS02705 536690..537655 + 966 WP_125144687.1 S9 family peptidase -
FGF54_RS02710 537739..538521 - 783 WP_168207984.1 mannosyltransferase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Addiction module killer protein, predicted

(3-96)

Antitoxin

Uncharacterized protein HI1420

(4-95)


Sequences

Toxin        


Download         Length: 105 a.a.        Molecular weight: 11659.36 Da        Isoelectric Point: 10.3355

>T126235 WP_137003032.1 NZ_CP040640:c533642-533328 [Agrobacterium sp. T29]
MNSFEKSAEFDEWLKALKDRAGKVRILHRLTAAEHGNFGDCEPVGGGVSEMRIHFGPGYRVYFTRVGKRIYFLLIGGDKS
SQKRDIKRAIGMAQTIGRDGRDGI

Download         Length: 315 bp

>T126235 NZ_CP040640:c533642-533328 [Agrobacterium sp. T29]
ATGAACAGCTTCGAGAAATCGGCGGAGTTCGACGAATGGCTGAAGGCTTTGAAAGATCGTGCCGGCAAGGTGCGGATTCT
TCATCGTCTCACGGCGGCGGAGCATGGGAATTTCGGCGATTGTGAGCCGGTGGGTGGAGGCGTTTCAGAAATGCGTATCC
ACTTCGGTCCCGGTTATCGGGTCTATTTCACTCGCGTTGGCAAGAGGATTTATTTCCTTCTGATCGGCGGGGACAAGTCT
TCGCAAAAGCGGGACATAAAACGCGCAATCGGGATGGCACAGACAATAGGAAGGGATGGCCGTGACGGAATTTAG

Antitoxin


Download         Length: 100 a.a.        Molecular weight: 10712.18 Da        Isoelectric Point: 4.6263

>AT126235 WP_080833761.1 NZ_CP040640:c533347-533048 [Agrobacterium sp. T29]
MAVTEFSQFDVSDYLDSDEAMIEYLAVAMEDENPDVFIAALGAVARARGMSHVADASGLGRESLYKALKPGSKLRYETVQ
KVLHALGFRLAVEKSLSAA

Download         Length: 300 bp

>AT126235 NZ_CP040640:c533347-533048 [Agrobacterium sp. T29]
ATGGCCGTGACGGAATTTAGCCAATTCGATGTGTCAGACTATCTGGATAGCGATGAAGCCATGATCGAATATCTGGCGGT
CGCAATGGAAGACGAAAACCCCGATGTCTTCATTGCCGCCCTTGGCGCGGTCGCCAGGGCGCGCGGAATGTCACATGTTG
CGGATGCTTCGGGTCTGGGTCGCGAAAGCCTCTACAAAGCACTTAAGCCCGGTTCGAAGCTTCGCTATGAAACCGTGCAG
AAAGTCCTGCATGCGCTGGGCTTCCGACTGGCCGTCGAAAAATCATTGAGTGCTGCGTAA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References