Detailed information of TA system TA126234

Bioinformatically predicted

Overview

TA module

• Type: II
• Classification (family/domain): parDE/CC2985(antitoxin)
• Location: 484646..485190
• Replicon: chromosome
• Accession: NZ_CP040640
• Organism: Agrobacterium sp. T29

Toxin (Protein)

• Gene name: parE
• Uniprot ID: -
• Locus tag: FGF54_RS02430
• Protein ID: WP_168207976.1
• Coordinates: 484900..485190 (+)
• Length: 97 a.a.

Antitoxin (Protein)

• Gene name: parD
• Uniprot ID: -
• Locus tag: FGF54_RS02425
• Protein ID: WP_142778826.1
• Coordinates: 484646..484897 (+)
• Length: 84 a.a.

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
FGF54_RS02390	479728..480417	-	690	WP_003520496.1	HAD family hydrolase	-
FGF54_RS02395	480640..481320	+	681	WP_065654301.1	GntR family transcriptional regulator	-
FGF54_RS02400	481366..481827	+	462	WP_142780104.1	DUF1284 domain-containing protein	-
FGF54_RS02405	481787..482887	-	1101	WP_142778825.1	hypothetical protein	-
FGF54_RS02415	483125..484270	+	1146	WP_003520492.1	site-specific DNA-methyltransferase	-
FGF54_RS02425	484646..484897	+	252	WP_142778826.1	type II toxin-antitoxin system ParD family antitoxin	Antitoxin
FGF54_RS02430	484900..485190	+	291	WP_168207976.1	type II toxin-antitoxin system RelE/ParE family toxin	Toxin
FGF54_RS02435	485228..485839	-	612	WP_035262998.1	HAD family phosphatase	-
FGF54_RS02440	485836..486948	-	1113	WP_142778828.1	A/G-specific adenine glycosylase	-
FGF54_RS02445	487075..487539	+	465	WP_142778829.1	hypothetical protein	-
FGF54_RS02450	487567..488088	+	522	WP_080817472.1	DUF721 domain-containing protein	-
FGF54_RS02455	488218..488898	+	681	WP_142778830.1	DsbA family protein	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

• Toxin-antitoxin system, RelE/ParE toxin family (4-92)

Antitoxin

• Antitoxin ParD (1-80)

Sequences

Toxin

Protein

• Length: 97 a.a.
• Molecular weight: 11270.00 Da
• Isoelectric Point: 6.2182

>T126234 WP_168207976.1 NZ_CP040640:484900-485190 [Agrobacterium sp. T29]
MGFRLSLLAEEDVIRIVEEGIVLFGLAQAQKYHRELYEIFELISLNPRMARERHELLPPLRIHRFRAHLVVYAVGADDDV
LIVRVRHAHEDWANES

Nucleotide

• Length: 291 bp

>T126234 NZ_CP040640:484900-485190 [Agrobacterium sp. T29]
ATGGGCTTTCGCCTGTCTCTGCTCGCGGAAGAGGACGTCATTCGCATAGTCGAAGAAGGCATCGTGTTATTCGGGCTGGC
GCAGGCGCAAAAATATCACCGGGAACTCTATGAGATATTTGAGCTGATATCTCTCAACCCACGAATGGCACGAGAGCGGC
ATGAGTTGTTACCGCCGCTGCGTATCCATCGGTTCAGGGCACATCTGGTTGTTTATGCCGTGGGAGCGGACGATGACGTC
CTGATCGTCCGCGTCCGCCACGCACATGAAGACTGGGCCAACGAGTCGTAG

Antitoxin

Protein

• Length: 84 a.a.
• Molecular weight: 9415.69 Da
• Isoelectric Point: 10.1452

>AT126234 WP_142778826.1 NZ_CP040640:484646-484897 [Agrobacterium sp. T29]
MATMNISLPAPMKEWVEAQSRTGRYSNASDYVRDLIRKDQERGEKIAAMQRFVDEGLRSGVGHRSQEALFAEAEARSMKR
KIG

Nucleotide

• Length: 252 bp

>AT126234 NZ_CP040640:484646-484897 [Agrobacterium sp. T29]
ATGGCGACCATGAACATATCGCTGCCTGCGCCCATGAAAGAATGGGTCGAGGCCCAATCCAGGACAGGTCGTTACTCCAA
TGCGAGTGACTACGTGCGAGACCTGATCCGCAAGGATCAGGAACGAGGCGAAAAAATCGCGGCGATGCAGCGTTTTGTGG
ATGAGGGACTGCGGAGTGGCGTCGGGCATCGCTCGCAGGAGGCCCTGTTCGCCGAGGCTGAAGCCCGCTCCATGAAACGC
AAAATCGGCTGA