Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) pasABC/RelE-HTH
Location 364598..365084 Replicon chromosome
Accession NZ_CP040640
Organism Agrobacterium sp. T29

Toxin (Protein)


Gene name pasB Uniprot ID -
Locus tag FGF54_RS01790 Protein ID WP_142778760.1
Coordinates 364598..364867 (-) Length 90 a.a.

Antitoxin (Protein)


Gene name pasA Uniprot ID A0A822V377
Locus tag FGF54_RS01795 Protein ID WP_003503188.1
Coordinates 364851..365084 (-) Length 78 a.a.

Genomic Context

FGF54_RS01755FGF54_RS01760FGF54_RS01770FGF54_RS01800FGF54_RS01805FGF54_RS01810FGF54_RS01765FGF54_RS01775FGF54_RS01785FGF54_RS01790FGF54_RS01795FGF54_RS01815FGF54_RS01820
Location: 359777..360406 (630 bp)
Type: Others
Protein ID: WP_142778755.1
Location: 360403..360846 (444 bp)
Type: Others
Protein ID: WP_142778756.1
Location: 361987..362904 (918 bp)
Type: Others
Protein ID: WP_020812649.1
Location: 365242..366762 (1521 bp)
Type: Others
Protein ID: WP_142778761.1
Location: 366931..368058 (1128 bp)
Type: Others
Protein ID: WP_142778762.1
Location: 368055..368747 (693 bp)
Type: Others
Protein ID: WP_142778763.1
Location: 360862..361905 (1044 bp)
Type: Others
Protein ID: WP_142778757.1
Location: 362957..363331 (375 bp)
Type: Others
Protein ID: WP_142778758.1
Location: 363827..364591 (765 bp)
Type: Others
Protein ID: WP_142778759.1
Location: 364598..364867 (270 bp)
Type: Toxin
Protein ID: WP_142778760.1
Location: 364851..365084 (234 bp)
Type: Antitoxin
Protein ID: WP_003503188.1
Location: 368815..369261 (447 bp)
Type: Others
Protein ID: WP_142778764.1
Location: 369413..369847 (435 bp)
Type: Others
Protein ID: WP_142778765.1
ToxinAntitoxinOther genes
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Locus tag
Coordinates
Strand
Size (bp)
Protein ID
Product
Description
FGF54_RS01755359777..360406+630WP_142778755.1DNA-3-methyladenine glycosylase I-
FGF54_RS01760360403..360846+444WP_142778756.1hypothetical protein-
FGF54_RS01765360862..361905-1044WP_142778757.1YeiH family protein-
FGF54_RS01770361987..362904+918WP_020812649.1LysR family transcriptional regulator-
FGF54_RS01775362957..363331-375WP_142778758.1DUF305 domain-containing protein-
FGF54_RS01785363827..364591-765WP_142778759.1hypothetical protein-
FGF54_RS01790364598..364867-270WP_142778760.1type II toxin-antitoxin system RelE/ParE family toxinToxin
FGF54_RS01795364851..365084-234WP_003503188.1ribbon-helix-helix protein, CopG familyAntitoxin
FGF54_RS01800365242..366762+1521WP_142778761.1histidine--tRNA ligase-
FGF54_RS01805366931..368058+1128WP_142778762.1ATP phosphoribosyltransferase regulatory subunit-
FGF54_RS01810368055..368747+693WP_142778763.1ATP phosphoribosyltransferase-
FGF54_RS01815368815..369261-447WP_142778764.1DoxX family protein-
FGF54_RS01820369413..369847-435WP_142778765.1hypothetical protein-

Associated MGEs

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MGE
detail
Similar
MGEs
Relative
position
MGE Type
Cargo ARG
Virulence gene
Coordinates
Length (bp)
No matching records found


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(5-88)

Antitoxin

Protein of unknown function DUF6290

(6-73)


Sequences

Toxin        


Download         Length: 90 a.a.        Molecular weight: 10415.94 Da        Isoelectric Point: 10.0404

>T126233 WP_142778760.1 NZ_CP040640:c364867-364598 [Agrobacterium sp. T29]
MTWRIEFQRAAVKQLGKLTKSDANRIVSFLADRIAEDDNPRRTGAALQGSELGNFWRYRVGDYRIICDIQDHKLVVLVVE
IGHRREIYR

Download         Length: 270 bp

>T126233 NZ_CP040640:c364867-364598 [Agrobacterium sp. T29]
TTGACCTGGAGAATTGAATTCCAGCGGGCTGCCGTCAAACAGCTGGGCAAGTTGACGAAGAGCGACGCCAATCGCATCGT
TTCCTTTCTGGCAGACCGGATTGCCGAAGATGACAATCCCCGCAGAACCGGCGCCGCCCTGCAAGGCTCCGAACTCGGAA
ATTTCTGGCGCTACCGGGTGGGCGATTACCGCATCATCTGCGATATACAGGATCACAAGCTCGTCGTGCTGGTGGTCGAA
ATCGGCCATCGCCGTGAAATCTACCGTTAG

Antitoxin


Download         Length: 78 a.a.        Molecular weight: 9212.31 Da        Isoelectric Point: 4.6044

>AT126233 WP_003503188.1 NZ_CP040640:c365084-364851 [Agrobacterium sp. T29]
MSKQTAIRLPDETYERLKALSERTGRTSAYYIREAIEKHIEDMEDLYLAEEATRQRIANKERTYTLEEVMRDLDLEN

Download         Length: 234 bp

>AT126233 NZ_CP040640:c365084-364851 [Agrobacterium sp. T29]
ATGAGCAAACAGACGGCCATACGCCTGCCGGACGAGACCTATGAGCGGCTGAAGGCGCTGTCCGAGCGCACCGGCCGTAC
ATCCGCCTATTACATCCGCGAGGCGATCGAGAAACATATCGAGGATATGGAAGATCTCTATCTTGCCGAAGAGGCGACGC
GGCAGCGCATCGCCAACAAGGAGCGCACCTATACTCTGGAAGAAGTGATGCGCGATCTTGACCTGGAGAATTGA

Similar Proteins

Only experimentally validated proteins are listed.

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Protein
Organism
Identities (%)
Coverage (%)
Ha-value
No matching records found
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Protein
Organism
Identities (%)
Coverage (%)
Ha-value
No matching records found

Structures

Toxin

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Source
ID
Structure
No matching records found

Antitoxin

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Source
ID
Structure
AlphaFold DBA0A822V377

References