Detailed information of TA system
Bioinformatically predictedOverview
TA module
Type | II | Classification (family/domain) | tsbAT/- |
Location | 1943439..1944215 | Replicon | chromosome |
Accession | NZ_CP040619 | ||
Organism | Staphylococcus aureus strain J01 |
Toxin (Protein)
Gene name | tsbT | Uniprot ID | X5E2E6 |
Locus tag | FF957_RS09710 | Protein ID | WP_000031108.1 |
Coordinates | 1943439..1943591 (-) | Length | 51 a.a. |
Antitoxin (Protein)
Gene name | tsbA | Uniprot ID | - |
Locus tag | FF957_RS09715 | Protein ID | WP_031806872.1 |
Coordinates | 1943616..1944215 (-) | Length | 200 a.a. |
Genomic Context
Location: 1939402..1940223 (822 bp)
Type: Others
Protein ID: WP_000669376.1
Type: Others
Protein ID: WP_000669376.1
Location: 1940686..1942071 (1386 bp)
Type: Others
Protein ID: WP_000116224.1
Type: Others
Protein ID: WP_000116224.1
Location: 1942267..1942662 (396 bp)
Type: Others
Protein ID: WP_000901021.1
Type: Others
Protein ID: WP_000901021.1
Location: 1943439..1943591 (153 bp)
Type: Toxin
Protein ID: WP_000031108.1
Type: Toxin
Protein ID: WP_000031108.1
Location: 1943616..1944215 (600 bp)
Type: Antitoxin
Protein ID: WP_031806872.1
Type: Antitoxin
Protein ID: WP_031806872.1
Location: 1944374..1944844 (471 bp)
Type: Others
Protein ID: WP_000181398.1
Type: Others
Protein ID: WP_000181398.1
Location: 1944849..1945976 (1128 bp)
Type: Others
Protein ID: WP_000379978.1
Type: Others
Protein ID: WP_000379978.1
Location: 1946127..1946849 (723 bp)
Type: Others
Protein ID: WP_000590809.1
Type: Others
Protein ID: WP_000590809.1
Location: 1946842..1948299 (1458 bp)
Type: Others
Protein ID: WP_000649907.1
Type: Others
Protein ID: WP_000649907.1
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Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
---|---|---|---|---|---|---|
FF957_RS09695 | 1939402..1940223 | + | 822 | WP_000669376.1 | RluA family pseudouridine synthase | - |
FF957_RS09700 | 1940686..1942071 | - | 1386 | WP_000116224.1 | class II fumarate hydratase | - |
FF957_RS09705 | 1942267..1942662 | - | 396 | WP_000901021.1 | hypothetical protein | - |
FF957_RS09710 | 1943439..1943591 | - | 153 | WP_000031108.1 | hypothetical protein | Toxin |
FF957_RS09715 | 1943616..1944215 | - | 600 | WP_031806872.1 | glucosamine-6-phosphate isomerase | Antitoxin |
FF957_RS09720 | 1944374..1944844 | - | 471 | WP_000181398.1 | tRNA (uridine(34)/cytosine(34)/5- carboxymethylaminomethyluridine(34)-2'-O)- methyltransferase TrmL | - |
FF957_RS09725 | 1944849..1945976 | - | 1128 | WP_000379978.1 | tRNA epoxyqueuosine(34) reductase QueG | - |
FF957_RS09730 | 1946127..1946849 | - | 723 | WP_000590809.1 | amino acid ABC transporter ATP-binding protein | - |
FF957_RS09735 | 1946842..1948299 | - | 1458 | WP_000649907.1 | ABC transporter permease subunit | - |
Associated MGEs
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MGE detail | Similar MGEs | Relative position | MGE Type | Cargo ARG | Virulence gene | Coordinates | Length (bp) |
---|---|---|---|---|---|---|---|
No matching records found |
Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.
Sequences
Toxin
Download Length: 51 a.a. Molecular weight: 5936.28 Da Isoelectric Point: 3.8962
>T126158 WP_000031108.1 NZ_CP040619:c1943591-1943439 [Staphylococcus aureus]
MSKDKDPKLNYHEEENSMVTDFEDLKELGKEMEQISDQNDQEKNSEEDSQ
MSKDKDPKLNYHEEENSMVTDFEDLKELGKEMEQISDQNDQEKNSEEDSQ
Download Length: 153 bp
>T126158 NZ_CP040619:c1943591-1943439 [Staphylococcus aureus]
ATGTCTAAAGACAAAGATCCAAAATTAAATTATCATGAAGAAGAAAACAGTATGGTAACGGATTTTGAAGATTTAAAAGA
ATTAGGTAAAGAAATGGAACAAATCTCTGATCAAAATGATCAAGAAAAGAATTCTGAAGAAGACAGTCAGTAA
ATGTCTAAAGACAAAGATCCAAAATTAAATTATCATGAAGAAGAAAACAGTATGGTAACGGATTTTGAAGATTTAAAAGA
ATTAGGTAAAGAAATGGAACAAATCTCTGATCAAAATGATCAAGAAAAGAATTCTGAAGAAGACAGTCAGTAA
Antitoxin
Download Length: 200 a.a. Molecular weight: 22333.43 Da Isoelectric Point: 5.1445
>AT126158 WP_031806872.1 NZ_CP040619:c1944215-1943616 [Staphylococcus aureus]
MAMNFKVFDNSQLVAEYAADIIRKQFNNNPTTIAGFHLDTDQASVLDELKKNVEKHAVDFSQINILDYDDKKSYFEALGV
PAGQVYPIAYEKDAIELIADKIKTKENKGKLTLQVVSIDEQGKLNVSIRQGLMEAREIFLVVTGANKRDVVEKLYQENGK
TSFEPADLKAHRMVNVILDKEAAAGLPEDVKAYFTSRFA
MAMNFKVFDNSQLVAEYAADIIRKQFNNNPTTIAGFHLDTDQASVLDELKKNVEKHAVDFSQINILDYDDKKSYFEALGV
PAGQVYPIAYEKDAIELIADKIKTKENKGKLTLQVVSIDEQGKLNVSIRQGLMEAREIFLVVTGANKRDVVEKLYQENGK
TSFEPADLKAHRMVNVILDKEAAAGLPEDVKAYFTSRFA
Download Length: 600 bp
>AT126158 NZ_CP040619:c1944215-1943616 [Staphylococcus aureus]
ATGGCAATGAACTTTAAAGTCTTTGACAATAGTCAACTTGTAGCAGAATATGCTGCTGATATTATTAGAAAGCAATTTAA
CAATAATCCTACTACAATTGCAGGTTTTCATTTAGATACAGATCAAGCGTCAGTTCTAGATGAATTAAAGAAAAATGTTG
AAAAACATGCTGTTGATTTTAGCCAAATAAATATTTTAGATTATGACGATAAAAAATCATATTTCGAAGCGTTAGGTGTA
CCAGCAGGTCAAGTTTATCCAATTGCTTATGAAAAAGATGCAATCGAATTAATCGCTGATAAGATTAAAACTAAAGAAAA
TAAAGGGAAATTAACATTACAAGTTGTTTCTATCGATGAGCAAGGTAAGTTAAATGTTAGTATTCGTCAAGGACTAATGG
AAGCAAGAGAAATTTTCTTAGTAGTGACAGGTGCTAATAAACGAGATGTAGTTGAAAAATTATATCAAGAAAATGGTAAA
ACAAGCTTCGAACCAGCCGATTTAAAAGCACATAGAATGGTAAATGTTATTCTTGATAAAGAAGCGGCTGCAGGTTTACC
TGAAGATGTTAAAGCTTACTTTACGTCACGCTTTGCTTAA
ATGGCAATGAACTTTAAAGTCTTTGACAATAGTCAACTTGTAGCAGAATATGCTGCTGATATTATTAGAAAGCAATTTAA
CAATAATCCTACTACAATTGCAGGTTTTCATTTAGATACAGATCAAGCGTCAGTTCTAGATGAATTAAAGAAAAATGTTG
AAAAACATGCTGTTGATTTTAGCCAAATAAATATTTTAGATTATGACGATAAAAAATCATATTTCGAAGCGTTAGGTGTA
CCAGCAGGTCAAGTTTATCCAATTGCTTATGAAAAAGATGCAATCGAATTAATCGCTGATAAGATTAAAACTAAAGAAAA
TAAAGGGAAATTAACATTACAAGTTGTTTCTATCGATGAGCAAGGTAAGTTAAATGTTAGTATTCGTCAAGGACTAATGG
AAGCAAGAGAAATTTTCTTAGTAGTGACAGGTGCTAATAAACGAGATGTAGTTGAAAAATTATATCAAGAAAATGGTAAA
ACAAGCTTCGAACCAGCCGATTTAAAAGCACATAGAATGGTAAATGTTATTCTTGATAAAGAAGCGGCTGCAGGTTTACC
TGAAGATGTTAAAGCTTACTTTACGTCACGCTTTGCTTAA
Structures
Toxin
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Source | ID | Structure |
---|---|---|
AlphaFold DB | X5E2E6 |
Antitoxin
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Source | ID | Structure |
---|---|---|
No matching records found |