Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type IV Classification (family/domain) cptAB/Cpta(toxin)
Location 3838061..3838718 Replicon chromosome
Accession NZ_CP040606
Organism Enterobacter ludwigii strain I42

Toxin (Protein)


Gene name cptA Uniprot ID -
Locus tag ELLBI42_RS18285 Protein ID WP_086532137.1
Coordinates 3838061..3838471 (-) Length 137 a.a.

Antitoxin (Protein)


Gene name cptB Uniprot ID -
Locus tag ELLBI42_RS18290 Protein ID WP_138614603.1
Coordinates 3838452..3838718 (-) Length 89 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
ELLBI42_RS18265 3834059..3835792 - 1734 WP_138614601.1 single-stranded-DNA-specific exonuclease RecJ -
ELLBI42_RS18270 3835798..3836511 - 714 WP_020883731.1 bifunctional protein-disulfide isomerase/oxidoreductase DsbC -
ELLBI42_RS18275 3836535..3837431 - 897 WP_014171511.1 site-specific tyrosine recombinase XerD -
ELLBI42_RS18280 3837533..3838054 + 522 WP_049023375.1 flavodoxin FldB -
ELLBI42_RS18285 3838061..3838471 - 411 WP_086532137.1 protein YgfX Toxin
ELLBI42_RS18290 3838452..3838718 - 267 WP_138614603.1 FAD assembly factor SdhE Antitoxin
ELLBI42_RS18295 3839013..3839993 + 981 WP_079231695.1 tRNA-modifying protein YgfZ -
ELLBI42_RS18300 3840104..3840763 - 660 WP_014171517.1 hemolysin III family protein -
ELLBI42_RS18305 3841030..3841761 + 732 WP_040018863.1 MurR/RpiR family transcriptional regulator -
ELLBI42_RS18310 3841878..3843311 + 1434 WP_032678925.1 6-phospho-beta-glucosidase BglA -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Inner membrane protein YgfX

(3-132)

Antitoxin

Flavinator of succinate dehydrogenase

(7-79)


Sequences

Toxin        


Download         Length: 137 a.a.        Molecular weight: 16199.12 Da        Isoelectric Point: 11.5020

>T126154 WP_086532137.1 NZ_CP040606:c3838471-3838061 [Enterobacter ludwigii]
VVLWQSDLRVSWRSQWMSLLLHGLVAAFVLLMPWPLSYTPLWLLLLSFVVFDSVRSQRRIHARQGEIKLLMDSRLRWQGK
EWEILGLPWMIASGMMLRLRSVDSGRRQHLWLAADSMDSAEWRDLRRMLLQQLTQE

Download         Length: 411 bp

>T126154 NZ_CP040606:c3838471-3838061 [Enterobacter ludwigii]
GTGGTCCTGTGGCAATCTGACCTTCGCGTCTCGTGGCGCTCGCAGTGGATGTCGTTGTTGCTCCACGGCCTGGTCGCGGC
CTTTGTGTTACTGATGCCGTGGCCGCTTAGCTATACGCCTCTGTGGTTGCTGTTGCTGTCGTTTGTGGTGTTTGACAGCG
TGCGCAGCCAGCGCCGCATTCATGCCCGTCAGGGGGAGATCAAATTACTGATGGATTCCCGCCTGCGCTGGCAGGGAAAA
GAGTGGGAAATTCTCGGTCTGCCCTGGATGATCGCTTCCGGCATGATGCTGCGGCTACGTAGCGTGGACAGCGGGCGTCG
CCAGCATCTGTGGCTGGCTGCGGACAGTATGGATAGCGCTGAGTGGCGGGACCTGCGTCGGATGTTATTACAGCAGCTGA
CGCAGGAGTAA

Antitoxin


Download         Length: 89 a.a.        Molecular weight: 10473.92 Da        Isoelectric Point: 4.6289

>AT126154 WP_138614603.1 NZ_CP040606:c3838718-3838452 [Enterobacter ludwigii]
MDINNKARIHWACRRGMRELDISIMPFFEYEYDSLSDDDKCLFVRLLESDDPDLFNWLMNHGKPADTELQRMVQLIQTRN
QERGPVAI

Download         Length: 267 bp

>AT126154 NZ_CP040606:c3838718-3838452 [Enterobacter ludwigii]
ATGGATATTAACAACAAGGCCCGTATTCACTGGGCGTGCCGTCGCGGCATGCGTGAACTTGATATTTCCATCATGCCTTT
CTTCGAATATGAGTATGACAGCTTAAGCGATGATGATAAGTGTCTGTTTGTTCGCCTGCTTGAGTCTGACGATCCTGATT
TATTTAACTGGCTGATGAATCACGGCAAACCCGCCGACACCGAGTTGCAACGGATGGTGCAATTAATTCAAACACGGAAT
CAGGAACGTGGTCCTGTGGCAATCTGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References