Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relBE/RelE-Phd
Location 1785076..1785599 Replicon chromosome
Accession NZ_CP040605
Organism Saccharopolyspora sp. ASAGF58

Toxin (Protein)


Gene name relE Uniprot ID -
Locus tag FDZ84_RS08190 Protein ID WP_168585397.1
Coordinates 1785339..1785599 (+) Length 87 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID -
Locus tag FDZ84_RS08185 Protein ID WP_168589896.1
Coordinates 1785076..1785342 (+) Length 89 a.a.

Genomic Context

FDZ84_RS08185FDZ84_RS08190FDZ84_RS08175FDZ84_RS08180FDZ84_RS08195FDZ84_RS08200FDZ84_RS08205
Location: 1785076..1785342 (267 bp)
Type: Antitoxin
Protein ID: WP_168589896.1
Location: 1785339..1785599 (261 bp)
Type: Toxin
Protein ID: WP_168585397.1
Location: 1782401..1784071 (1671 bp)
Type: Others
Protein ID: WP_168589895.1
Location: 1784074..1784787 (714 bp)
Type: Others
Protein ID: WP_168585396.1
Location: 1785832..1787397 (1566 bp)
Type: Others
Protein ID: WP_168585398.1
Location: 1787394..1788068 (675 bp)
Type: Others
Protein ID: WP_168589897.1
Location: 1788166..1789638 (1473 bp)
Type: Others
Protein ID: WP_168585399.1
ToxinAntitoxinOther genes
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Locus tag
Coordinates
Strand
Size (bp)
Protein ID
Product
Description
FDZ84_RS081751782401..1784071-1671WP_168589895.1DNA polymerase Y family protein-
FDZ84_RS081801784074..1784787-714WP_168585396.1hypothetical protein-
FDZ84_RS081851785076..1785342+267WP_168589896.1type II toxin-antitoxin system Phd/YefM family antitoxinAntitoxin
FDZ84_RS081901785339..1785599+261WP_168585397.1type II toxin-antitoxin system RelE/ParE family toxinToxin
FDZ84_RS081951785832..1787397-1566WP_168585398.1bifunctional phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase-
FDZ84_RS082001787394..1788068-675WP_168589897.1phosphoribosylglycinamide formyltransferase-
FDZ84_RS082051788166..1789638-1473WP_168585399.1hypothetical protein-

Associated MGEs

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MGE
detail
Similar
MGEs
Relative
position
MGE Type
Cargo ARG
Virulence gene
Coordinates
Length (bp)
No matching records found


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(11-85)

Antitoxin

Type II toxin-antitoxin system, antitoxin Phd/YefM

(1-72)


Sequences

Toxin        


Download         Length: 87 a.a.        Molecular weight: 9606.10 Da        Isoelectric Point: 9.5794

>T126138 WP_168585397.1 NZ_CP040605:1785339-1785599 [Saccharopolyspora sp. ASAGF58]
VTYTIKITARAGRDLACFPEKVASACAEFIFGPLAENPHRLGKPLFGEFKGLHSARRSAYRVVYAIQDDTVVVEVVRIAH
RADVYR

Download         Length: 261 bp

>T126138 NZ_CP040605:1785339-1785599 [Saccharopolyspora sp. ASAGF58]
GTGACCTACACGATCAAGATCACCGCACGTGCAGGGCGCGACCTCGCATGCTTCCCGGAGAAGGTCGCATCGGCTTGCGC
CGAGTTCATCTTCGGGCCGCTGGCCGAGAACCCGCACCGGCTCGGCAAACCACTGTTCGGAGAGTTCAAGGGCCTGCACT
CGGCTCGACGGAGCGCGTACCGCGTGGTGTACGCGATTCAAGACGACACCGTGGTGGTCGAAGTCGTCCGGATCGCCCAT
CGAGCCGACGTCTACCGATAG

Antitoxin


Download         Length: 89 a.a.        Molecular weight: 9659.72 Da        Isoelectric Point: 4.1851

>AT126138 WP_168589896.1 NZ_CP040605:1785076-1785342 [Saccharopolyspora sp. ASAGF58]
MTTIPLGEARDRLSEVVAQVESTHDRVEITRHGRPAAVLISPDDLSSLEETLDLLTTPGEAEAIREGVADAAAERFVDTE
EIKSRYLQ

Download         Length: 267 bp

>AT126138 NZ_CP040605:1785076-1785342 [Saccharopolyspora sp. ASAGF58]
ATGACGACGATCCCATTAGGAGAAGCTCGCGACCGGCTGTCAGAGGTGGTCGCGCAGGTCGAGAGCACCCATGATCGAGT
TGAAATCACCCGGCATGGTCGACCCGCCGCGGTCCTCATCTCCCCCGACGACCTGTCGTCCCTAGAAGAGACCCTGGACC
TACTGACCACTCCCGGCGAGGCGGAGGCCATTCGGGAGGGCGTGGCAGACGCGGCAGCGGAGCGCTTCGTTGACACCGAA
GAAATCAAGAGTCGCTACCTGCAGTGA

Similar Proteins

Only experimentally validated proteins are listed.

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Protein
Organism
Identities (%)
Coverage (%)
Ha-value
No matching records found
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Protein
Organism
Identities (%)
Coverage (%)
Ha-value
No matching records found

Structures

Toxin

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Source
ID
Structure
No matching records found

Antitoxin

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Source
ID
Structure
No matching records found

References