Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) vapBC/PHD(antitoxin)
Location 1108821..1109485 Replicon chromosome
Accession NZ_CP040605
Organism Saccharopolyspora sp. ASAGF58

Toxin (Protein)


Gene name vapC Uniprot ID -
Locus tag FDZ84_RS04930 Protein ID WP_168584913.1
Coordinates 1108821..1109216 (-) Length 132 a.a.

Antitoxin (Protein)


Gene name vapB Uniprot ID -
Locus tag FDZ84_RS04935 Protein ID WP_168589814.1
Coordinates 1109213..1109485 (-) Length 91 a.a.

Genomic Context

FDZ84_RS04910FDZ84_RS04915FDZ84_RS04920FDZ84_RS04925FDZ84_RS04930FDZ84_RS04935FDZ84_RS04940FDZ84_RS04945FDZ84_RS04950
Location: 1104990..1105709 (720 bp)
Type: Others
Protein ID: WP_168584909.1
Location: 1105734..1105982 (249 bp)
Type: Others
Protein ID: WP_168584910.1
Location: 1106081..1107601 (1521 bp)
Type: Others
Protein ID: WP_168584911.1
Location: 1107824..1108681 (858 bp)
Type: Others
Protein ID: WP_168584912.1
Location: 1108821..1109216 (396 bp)
Type: Toxin
Protein ID: WP_168584913.1
Location: 1109213..1109485 (273 bp)
Type: Antitoxin
Protein ID: WP_168589814.1
Location: 1109543..1111366 (1824 bp)
Type: Others
Protein ID: WP_168584914.1
Location: 1111460..1112296 (837 bp)
Type: Others
Protein ID: WP_168589815.1
Location: 1112493..1113647 (1155 bp)
Type: Others
Protein ID: WP_168584915.1
ToxinAntitoxinOther genes
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Locus tag
Coordinates
Strand
Size (bp)
Protein ID
Product
Description
FDZ84_RS049101104990..1105709+720WP_168584909.1FadR family transcriptional regulator-
FDZ84_RS049151105734..1105982-249WP_168584910.1type II toxin-antitoxin system prevent-host-death family antitoxin-
FDZ84_RS049201106081..1107601-1521WP_168584911.1cobyric acid synthase-
FDZ84_RS049251107824..1108681-858WP_168584912.1type I methionyl aminopeptidase-
FDZ84_RS049301108821..1109216-396WP_168584913.1type II toxin-antitoxin system VapC family toxinToxin
FDZ84_RS049351109213..1109485-273WP_168589814.1type II toxin-antitoxin system prevent-host-death family antitoxinAntitoxin
FDZ84_RS049401109543..1111366-1824WP_168584914.1penicillin-binding protein-
FDZ84_RS049451111460..1112296-837WP_168589815.1GNAT family N-acetyltransferase-
FDZ84_RS049501112493..1113647-1155WP_168584915.1flavodoxin-dependent (E)-4-hydroxy-3-methylbut-2-enyl-diphosphate synthase-

Associated MGEs

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MGE
detail
Similar
MGEs
Relative
position
MGE Type
Cargo ARG
Virulence gene
Coordinates
Length (bp)
No matching records found


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

PIN domain

(2-113)

Antitoxin

Type II toxin-antitoxin system, antitoxin Phd/YefM

(1-41)


Sequences

Toxin        


Download         Length: 132 a.a.        Molecular weight: 14090.13 Da        Isoelectric Point: 5.1702

>T126137 WP_168584913.1 NZ_CP040605:c1109216-1108821 [Saccharopolyspora sp. ASAGF58]
MIYFDSSALIKLIAPEPESKALSQWIRERWEHPRVTSALSKVDVLRTFREVGPAAEDLASIIVSKIDQLPVKQDVLDVAT
ELRGNVGPVDAIHLASACKIKNGLHAYVSYDPALLAAAEEAGLTTASPGAN

Download         Length: 396 bp

>T126137 NZ_CP040605:c1109216-1108821 [Saccharopolyspora sp. ASAGF58]
TTGATCTATTTCGATTCCTCCGCGCTGATCAAGTTGATCGCCCCCGAGCCGGAGAGCAAGGCGCTGAGCCAATGGATCCG
CGAGCGCTGGGAACACCCCCGCGTGACCAGCGCGTTGTCGAAGGTCGACGTGCTGCGCACCTTCCGTGAGGTAGGGCCGG
CCGCCGAAGACCTGGCGTCGATCATCGTGTCGAAGATCGACCAGCTGCCGGTGAAGCAGGACGTGCTCGACGTGGCCACC
GAGCTGCGTGGCAACGTCGGCCCGGTGGACGCCATCCACCTGGCCTCCGCGTGCAAGATCAAGAACGGTCTGCATGCCTA
CGTCTCGTACGATCCGGCGCTACTGGCTGCGGCGGAAGAAGCAGGGCTGACCACGGCCTCACCAGGCGCGAACTGA

Antitoxin


Download         Length: 91 a.a.        Molecular weight: 10022.38 Da        Isoelectric Point: 6.3673

>AT126137 WP_168589814.1 NZ_CP040605:c1109485-1109213 [Saccharopolyspora sp. ASAGF58]
MERIGVRELRQNASRYLKRVAAGESILVTDRGRTVAVLSPPTRDQTLYDELVAAGELIPGEGGELPEPLPAAPTPNVSDR
LLRRREQERF

Download         Length: 273 bp

>AT126137 NZ_CP040605:c1109485-1109213 [Saccharopolyspora sp. ASAGF58]
ATGGAGCGGATCGGCGTTCGTGAGCTGCGGCAGAACGCCAGTCGATACCTGAAGCGGGTCGCCGCCGGCGAATCGATCCT
CGTGACCGATCGGGGGCGCACCGTCGCGGTGCTAAGTCCGCCCACGCGTGACCAAACCCTGTACGACGAACTCGTCGCAG
CCGGAGAGCTCATCCCCGGCGAAGGCGGCGAGCTCCCCGAACCGTTGCCGGCAGCGCCGACCCCGAACGTCTCCGACCGG
CTGCTGCGCAGGCGTGAACAGGAGCGGTTTTGA

Similar Proteins

Only experimentally validated proteins are listed.

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Protein
Organism
Identities (%)
Coverage (%)
Ha-value
No matching records found
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Protein
Organism
Identities (%)
Coverage (%)
Ha-value
No matching records found

Structures

Toxin

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Source
ID
Structure
No matching records found

Antitoxin

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Source
ID
Structure
No matching records found

References