Detailed information of TA system TA126134

Bioinformatically predicted

Overview

TA module

• Type: II
• Classification (family/domain): relB-parE/ParE-RHH
• Location: 2164282..2164838
• Replicon: chromosome
• Accession: NZ_CP040604
• Organism: Xanthomonas oryzae pv. oryzae strain IXO704

Toxin (Protein)

• Gene name: parE
• Uniprot ID: -
• Locus tag: IXO704_RS10350
• Protein ID: WP_027703932.1
• Coordinates: 2164548..2164838 (+)
• Length: 97 a.a.

Antitoxin (Protein)

• Gene name: relB
• Uniprot ID: A0A854CIX2
• Locus tag: IXO704_RS10345
• Protein ID: WP_011408759.1
• Coordinates: 2164282..2164560 (+)
• Length: 93 a.a.

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
IXO704_RS10325	2160466..2161701	+	1236	WP_011257570.1	ISL3-like element ISXoo13 family transposase	-
IXO704_RS10330	2162030..2163265	-	1236	WP_011257310.1	ISL3-like element ISXoo13 family transposase	-
IXO704_RS10335	2163597..2163797	+	201	WP_027703931.1	ribbon-helix-helix protein, CopG family	-
IXO704_RS23475	2163742..2164086	+	345	WP_199285675.1	hypothetical protein	-
IXO704_RS23480	2163998..2164201	+	204	WP_199285669.1	hypothetical protein	-
IXO704_RS10345	2164282..2164560	+	279	WP_011408759.1	CopG family ribbon-helix-helix protein	Antitoxin
IXO704_RS10350	2164548..2164838	+	291	WP_027703932.1	type II toxin-antitoxin system RelE/ParE family toxin	Toxin
IXO704_RS10355	2165099..2165296	+	198	WP_004541336.1	hypothetical protein	-
IXO704_RS10360	2165440..2165619	+	180	WP_015463309.1	hypothetical protein	-
IXO704_RS10375	2166483..2166884	-	402	WP_011259345.1	H-NS histone family protein	-
IXO704_RS10380	2167106..2167282	+	177	Protein_1944	DUF3606 domain-containing protein	-
IXO704_RS10385	2167298..2167504	+	207	Protein_1945	hypothetical protein	-
IXO704_RS10390	2167564..2167880	+	317	Protein_1946	ATP-dependent DNA ligase	-
IXO704_RS10395	2167977..2169068	-	1092	WP_075239568.1	ribonuclease D	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

• Toxin-antitoxin system, RelE/ParE toxin family (4-94)

Antitoxin

• Ribbon-helix-helix protein, CopG (5-42)

Sequences

Toxin

Protein

• Length: 97 a.a.
• Molecular weight: 10915.48 Da
• Isoelectric Point: 9.5554

>T126134 WP_027703932.1 NZ_CP040604:2164548-2164838 [Xanthomonas oryzae pv. oryzae]
MPQVIFAPAAIGDMLRLREFLRPKNPDAARRAGEAIRRGVQALGAHPRMGRLIEDLSEQYREWLIDFGDSGYVARYRFDG
DTVTILAVRHQKEAGY

Nucleotide

• Length: 291 bp

>T126134 NZ_CP040604:2164548-2164838 [Xanthomonas oryzae pv. oryzae]
ATGCCACAAGTAATCTTTGCGCCGGCGGCGATCGGGGACATGCTACGGCTGCGTGAATTCCTGAGGCCGAAGAATCCCGA
TGCCGCGAGGCGGGCCGGCGAAGCGATTAGGCGCGGCGTCCAGGCTCTCGGTGCCCACCCTCGAATGGGGCGGCTCATAG
AAGATCTGTCTGAACAGTATCGGGAGTGGCTTATCGATTTTGGGGATAGCGGCTATGTGGCTCGGTACCGCTTCGATGGG
GATACCGTCACGATTTTGGCCGTGCGACACCAGAAGGAAGCGGGGTACTGA

Antitoxin

Protein

• Length: 93 a.a.
• Molecular weight: 10826.11 Da
• Isoelectric Point: 4.9736

>AT126134 WP_011408759.1 NZ_CP040604:2164282-2164560 [Xanthomonas oryzae pv. oryzae]
MVTATSIKLDDELKGRVQHLAESRRRTPHWIMREAIEQYVEREEKREALNRDTLKAWDEFQATGLHVTAEEVDKWLASWG
TDDELPPPECHK

Nucleotide

• Length: 279 bp

>AT126134 NZ_CP040604:2164282-2164560 [Xanthomonas oryzae pv. oryzae]
ATGGTTACGGCAACTTCCATCAAGCTTGATGATGAATTGAAAGGGCGGGTTCAGCACTTGGCAGAGTCGCGCCGGCGTAC
CCCGCATTGGATCATGCGCGAAGCCATTGAGCAGTACGTCGAGCGCGAGGAAAAGCGCGAGGCGCTGAACCGGGACACGC
TCAAGGCATGGGATGAATTTCAGGCGACTGGCCTGCATGTGACCGCTGAGGAAGTGGACAAGTGGCTCGCGAGCTGGGGA
ACTGACGACGAACTGCCTCCGCCAGAATGCCACAAGTAA

Structures

Antitoxin

• AlphaFold DB: A0A854CIX2