Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type II Classification (family/domain) EcnAB/-
Location 419226..419576 Replicon chromosome
Accession NZ_CP040604
Organism Xanthomonas oryzae pv. oryzae strain IXO704

Toxin (Protein)


Gene name EcnB Uniprot ID G7TLC7
Locus tag IXO704_RS02115 Protein ID WP_011257368.1
Coordinates 419442..419576 (+) Length 45 a.a.

Antitoxin (Protein)


Gene name EcnA Uniprot ID G7TLC8
Locus tag IXO704_RS02110 Protein ID WP_011407410.1
Coordinates 419226..419378 (+) Length 51 a.a.

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
IXO704_RS02085 415497..416180 - 684 WP_011257363.1 dTMP kinase -
IXO704_RS02090 416660..416956 - 297 WP_012446308.1 hypothetical protein -
IXO704_RS02095 416963..417202 - 240 WP_011257365.1 hypothetical protein -
IXO704_RS02100 417199..417873 - 675 WP_011257366.1 hypothetical protein -
IXO704_RS02105 418195..419118 + 924 WP_011407409.1 arginase -
IXO704_RS02110 419226..419378 + 153 WP_011407410.1 entericidin A/B family lipoprotein Antitoxin
IXO704_RS02115 419442..419576 + 135 WP_011257368.1 entericidin A/B family lipoprotein Toxin
IXO704_RS02120 419820..420029 + 210 WP_011407411.1 CsbD family protein -
IXO704_RS02125 420198..421487 + 1290 WP_011257370.1 tryptophan--tRNA ligase -
IXO704_RS02130 421540..422562 + 1023 WP_011257371.1 MBL fold metallo-hydrolase -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains


Predicted by InterproScan

Toxin

(23-42)

Antitoxin

(23-42)


Sequences


Toxin        


Download         Length: 45 a.a.        Molecular weight: 4457.33 Da        Isoelectric Point: 10.2040

>T126133 WP_011257368.1 NZ_CP040604:419442-419576 [Xanthomonas oryzae pv. oryzae]
MKRAIVLLVLSMLSVGLLSGCNTVAGAGKDVKGAGEKVEDAARK

Download         Length: 135 bp

>T126133 NZ_CP040604:419442-419576 [Xanthomonas oryzae pv. oryzae]
ATGAAGCGTGCAATTGTGCTGCTCGTGCTGTCCATGTTGTCGGTCGGTCTGCTGTCGGGCTGCAACACCGTCGCAGGTGC
CGGCAAGGACGTGAAGGGCGCCGGCGAGAAGGTGGAAGACGCAGCGCGTAAGTAA

Antitoxin


Download         Length: 51 a.a.        Molecular weight: 5046.99 Da        Isoelectric Point: 8.7942

>AT126133 WP_011407410.1 NZ_CP040604:419226-419378 [Xanthomonas oryzae pv. oryzae]
MKRLLTLMVLGLFSAGVMTGCNTVAGAGKDLQGAGGKVEKTAEKCSDGKC

Download         Length: 153 bp

>AT126133 NZ_CP040604:419226-419378 [Xanthomonas oryzae pv. oryzae]
ATGAAGCGACTGCTGACACTGATGGTGCTGGGCCTGTTTTCGGCCGGCGTGATGACGGGCTGCAACACCGTGGCTGGCGC
TGGCAAGGACTTGCAGGGCGCGGGTGGGAAGGTCGAGAAAACGGCCGAAAAATGCAGCGATGGTAAGTGCTGA

Similar Proteins


Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures


Toxin

Source ID Structure
AlphaFold DB A0A0C5UG40


Antitoxin

Source ID Structure
AlphaFold DB A0A0C5V759

References