Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relBE/YafQ-DinJ
Location 630219..630775 Replicon chromosome
Accession NZ_CP040576
Organism Furfurilactobacillus rossiae strain RS

Toxin (Protein)


Gene name relE Uniprot ID A0A0R1R9Y6
Locus tag LROSRS0_RS02720 Protein ID WP_017260399.1
Coordinates 630593..630775 (+) Length 61 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID A0A0R1RJ26
Locus tag LROSRS0_RS02715 Protein ID WP_017260400.1
Coordinates 630219..630494 (+) Length 92 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
LROSRS0_RS02685 625838..626422 + 585 WP_017260406.1 hypothetical protein -
LROSRS0_RS02690 626536..627387 - 852 WP_017260405.1 SDR family oxidoreductase -
LROSRS0_RS02695 627415..628278 - 864 WP_017260404.1 NAD(P)H-binding protein -
LROSRS0_RS02700 628311..628742 - 432 WP_017260403.1 Rrf2 family transcriptional regulator -
LROSRS0_RS02705 628835..629314 - 480 WP_017260402.1 MerR family transcriptional regulator -
LROSRS0_RS02710 629387..629947 + 561 WP_017260401.1 sugar O-acetyltransferase -
LROSRS0_RS02715 630219..630494 + 276 WP_017260400.1 type II toxin-antitoxin system RelB/DinJ family antitoxin Antitoxin
LROSRS0_RS02720 630593..630775 + 183 WP_017260399.1 type II toxin-antitoxin system YafQ family toxin Toxin
LROSRS0_RS02725 630979..631350 + 372 WP_017260398.1 cupredoxin domain-containing protein -
LROSRS0_RS02730 631432..633366 + 1935 WP_017260397.1 copper-translocating P-type ATPase -
LROSRS0_RS02735 633578..634756 - 1179 WP_017260395.1 MFS transporter -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(12-58)

Antitoxin

RelB antitoxin/Antitoxin DinJ

(11-86)


Sequences

Toxin        


Download         Length: 61 a.a.        Molecular weight: 6821.83 Da        Isoelectric Point: 6.4725

>T126107 WP_017260399.1 NZ_CP040576:630593-630775 [Furfurilactobacillus rossiae]
MLASTNTVGSVYHDHQLTGRLNGFRELHIEPDWLLIYKRDDAKLILLIVDTGSHAQLFGM

Download         Length: 183 bp

>T126107 NZ_CP040576:630593-630775 [Furfurilactobacillus rossiae]
ATGCTCGCCAGTACAAATACAGTTGGTAGTGTCTATCATGATCATCAATTAACGGGGCGTCTAAATGGCTTTCGTGAACT
TCATATTGAACCAGACTGGTTACTTATTTACAAACGTGATGATGCAAAATTAATTTTGTTGATTGTGGATACCGGGAGTC
ATGCTCAATTATTTGGCATGTAA

Antitoxin


Download         Length: 92 a.a.        Molecular weight: 10038.36 Da        Isoelectric Point: 4.4482

>AT126107 WP_017260400.1 NZ_CP040576:630219-630494 [Furfurilactobacillus rossiae]
MSIKTAKKINLNVKIDPDLKQKADTVFENMGITTSAGVMLFIKRVVDDQELPFTPRVATGVDKALQDLETGNTHSAKSPQ
QMFDELDGDDD

Download         Length: 276 bp

>AT126107 NZ_CP040576:630219-630494 [Furfurilactobacillus rossiae]
ATGAGCATAAAAACAGCAAAAAAAATAAACTTAAATGTTAAAATTGATCCCGATTTAAAACAAAAAGCAGATACTGTTTT
TGAGAATATGGGTATCACAACGAGTGCTGGGGTCATGTTATTCATTAAGCGAGTGGTGGATGACCAAGAGTTACCGTTTA
CACCACGTGTTGCGACTGGTGTTGATAAGGCCCTGCAGGATTTAGAAACCGGTAATACACATTCTGCAAAGTCACCACAA
CAAATGTTCGATGAGTTGGATGGTGACGATGACTGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A0R1R9Y6

Antitoxin

Source ID Structure
AlphaFold DB A0A0R1RJ26

References