Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 3316705..3316976 Replicon chromosome
Accession NZ_CP040572
Organism Escherichia coli O157:H7 strain ECP17-46

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 3316743..3316846 (-)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 3316705..3316976 (+)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
FGA21_RS17350 3313862..3315301 + 1440 WP_001302304.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -
FGA21_RS17355 3315419..3315655 + 237 WP_001295499.1 DUF1480 family protein -
FGA21_RS17360 3315760..3315951 + 192 WP_001296140.1 YebW family protein -
FGA21_RS17365 3315952..3316608 - 657 WP_000812736.1 protein-serine/threonine phosphatase -
- 3316705..3316976 + 272 - - Antitoxin
- 3316743..3316846 - 104 - - Toxin
FGA21_RS17370 3317004..3317345 - 342 WP_000976483.1 YebY family protein -
FGA21_RS17375 3317358..3318230 - 873 WP_000879314.1 copper homeostasis membrane protein CopD -
FGA21_RS17380 3318234..3318608 - 375 WP_000168751.1 CopC domain-containing protein YobA -
FGA21_RS17385 3318747..3318977 + 231 WP_000916763.1 DNA polymerase III subunit theta -
FGA21_RS17390 3319079..3319735 + 657 WP_000011656.1 carbon-nitrogen hydrolase family protein -
FGA21_RS17395 3319759..3320421 + 663 WP_000944244.1 exodeoxyribonuclease X -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 104 bp

>T126084 NZ_CP040572:c3316846-3316743 [Escherichia coli O157:H7]
GGCAAGGCAACTAAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATAC
AGGAATCGTGTTCGGTCTCTTTTT

Antitoxin


Download         Length: 272 bp

>AT126084 NZ_CP040572:3316705-3316976 [Escherichia coli O157:H7]
AAAGTCAGCGAAGGAAATGCTTCTGGCTTTTAACAGATAAAAAGAGACCGAACACGATTCCTGTATTCGGTCCAGGGAAA
TGGCTCTTGGGAGAGAGCCGTGCGCTAAAAGTTGGCATTAATGCAGGCTTAGTTGCCTTGCCCTTTAAGAATAGATGACG
ACGCCAGGTTTTCCAGTTTGCGTGCAAAATGGTCAATAAAAAGCGCGGTGGTCATCAGCTTAAATGTTAAAAACCGCCCG
TTCTGGTGAAAGAACTGAGGCGGTTTTTTTAT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References